The Apocynaceae species inventory of the Ibitipoca State Park is presented. The Park is located in Mantiqueira Range, between 21º40'15" - 21º43'30" S and 43º52'35" -43º54'15" W. Within the Park there are several types of vegetation, such as altitude savannas, montane forests and mostly campos rupestres. The Apocynaceae, including Asclepiadoideae, has a cosmopolitan distribution, with about 415 genera and 4550 species, from which about 870 occur in Brazil, in a great range of habitats. Ten genera and 28 species occur in the Park.: Aspidosperma olivaceum, A. spruceanum, Blepharodon ampliflorum, Condylocarpon isthmicum, Ditassa acerosa, D. bicolor, D. conceptionis, D. cordata, D. laevis, D. linearis, D. mucronata, D. tomentosa, Forsteronia australis, F. velloziana, Jobinia lindbergii, Mandevilla atroviolacea, M. illustris, M. pohliana, M. sellowii, M. tenuifolia, Orthosia scoparia, Oxypetalum appendiculatum, O. insigne, O. lanatum, O. minarum, O. patulum, O. strictum, and Peplonia organensis. Keys for the genera and species, descriptions, illustrations, and comments about the distribution and phenology of the species are presented.