Special Reference Research Articles

Diagnosis and management of Canine Renal Cell Carcinoma with special reference to Shear Wave Elastography

This report focuses on the diagnosis and surgical management of unilateral renal cell carcinoma in a 7-year-old male intact German Shepherd dog. The dog was presented with fever, haematuria, inappetence, infrequent bouts of emesis, and progressive weight loss. Palpation revealed a hard, round mass in the right cranial abdomen. A presumptive diagnosis of unilateral renal neoplasm was made based on clinical signs, haematobiochemical analysis, and radiography. B-mode ultrasound examination demonstrated an enlarged right kidney extending up to the ventral midline. The kidney exhibited heterogenous echotexture, loss of renal architecture, and only a small healthy portion at the caudal pole. Point Shear Wave Elastography analysis revealed elevated values both in terms Shear Wave Velocity (m/sec) and Young’s Modulus Stiffness Value (kPa), indicating the presence of renal malignancy. To treat the condition, unilateral nephroureterectomy was performed under general anaesthesia. Histopathological examination confirmed the diagnosis of renal cell carcinoma. Consequently, it can be concluded that B-mode ultrasonography, Point Shear Wave Elastography, and nephroureterectomy played crucial roles in the successful diagnosis and surgical management of unilateral renal cell carcinoma.

MIC trends of vancomycin and teicoplanin among methicillin resistant CoNS isolates from new born blood cultures in a tertiary care centre in Southern India.

Coagulase-negative-Staphylococci (CoNS) are important etiological agent of bacteraemia in newborn babies. Methicillin resistant CoNS infections have only limited treatment options. The antimicrobial susceptibility pattern of Methicillin Resistant CoNS isolates from newborn blood cultures was studied with special reference to MICs of Vancomycin and Teicoplanin. The study population included Methicillin Resistant Coagulase Negative Staphylococcal isolates (MRCoNS) from newborn blood cultures, during a one-year period. Minimum inhibitory concentration (MIC) of Vancomycin and Teicoplanin in Methicillin resistant CoNS isolates was determined by macrobroth dilution method as per CLSI guidelines and by automated methods. Coagulase Negative Staphylococci were the etiological agent in 73.7% (n=56) cases of neonatal bacteremia. Methicillin resistance in newborn CoNS was found to be 58.9%. All the MRCoNS isolates had vancomycin and teicoplanin MICs in the susceptible range. There were MRCoNS isolates with MICs in the upper limit of susceptible range for both vancomycin and teicoplanin, which can result in poor clinical response. Continuous large scale multi-centre surveillance studies with special attention to study the MIC pattern of the high-end anti-MRSA agents like vancomycin, teicoplanin, linezolid are to be carried out. This will help the clinicians to judiciously prescribe the antibiotics, which is very essential for antimicrobial stewardship.

The Importance of Digital Records for Scientific Research Work in Archives (with Special Reference to the Archives of the Tuzla Canton)

Digital material holds particular significance for scientific research in archives. Digitization of archival material enables researchers worldwide to access archival material without the need to physically visit the archives. Digital material allows for faster searching and identification of relevant information in archival holdings and collections through keywords, metadata, or even text recognition technologies. This facilitates researchersʾ efficient access to the information they need for their work. Digital material enables the sharing of archival material with other researchers or institutions, fostering collaboration and knowledge exchange. Through digital platforms, researchers can easily access, review, and utilize archival material in their research. In short, digital material transforms the way archival material is accessed and used in scientific research, enabling broader availability, better searchability, more efficient analysis, and greater collaboration among researchers. This contributes to the advancement of scientific research and the preservation of cultural heritage. The author will try to point out the importance of digital records for scientific and research work in archives, with special reference to the Archives of the Tuzla Canton. Data on the number of researchers who used the archives’ services for scientific research purposes for the period 2020-2023 will be presented and with all the difficulties the researchers encountered. Also, based on the survey, we will present data on researchers from other archives in Bosnia and Herzegovina, who used digital records in their research, in order to be able to compare the scientific-research component in the archives of Bosnia and Herzegovina.

Selected aspects of tuberculosis treatment with special reference to alcoholism

Selected aspects of tuberculosis treatment with special reference to alcoholism

A study on the impact of HR policy on health and safety measures with special reference to patspin india Ltd

A study on the impact of HR policy on health and safety measures with special reference to patspin india Ltd

An emperical study on customer preference of branded vehicles with special reference to Anaamalais motors at Thanjavur

An emperical study on customer preference of branded vehicles with special reference to Anaamalais motors at Thanjavur

Recruitment and selection process in IBACUS TECH with special reference to coimbatore

Recruitment and selection process in IBACUS TECH with special reference to coimbatore

A study on impact of training and development of employee performance with special reference to promt infotech,coimbatore

A study on impact of training and development of employee performance with special reference to promt infotech,coimbatore

An efficient moving-mesh strategy for predicting crack propagation in unidirectional composites: Application to materials reinforced with aligned CNTs

This paper presents an efficient numerical approach for reproducing the process of crack propagation inside unidirectional composites subjected to general loading conditions, with special reference to epoxy materials enhanced with embedded aligned CNTs. This approach involves a traditional FE framework improved by the Moving Mesh (MM) technique based on the Arbitrary Lagrangian-Eulerian (ALE) formulation and the Interaction Integral Method (M−integral). The MM serves as a powerful numerical tool to simulate the discrete crack advance with minimal remeshing, thus reducing the computational complexities. Instead, the M−Integral method, formulated for generally anisotropic materials, has been employed to extract the mixed-mode Stress Intensity Factors (SIFs), which are necessary to define the crack onset condition and propagation direction on the basis of the modified Maximum Hoop Stress Criterion. The proposed strategy includes the extended rule of mixtures to evaluate the homogenized elastic properties of nano-reinforced composites. The validity of the proposed methodology has been assessed through comparisons with experimental data and numerical results available in the literature.

A Review of Alternate Dispute Resolution (ADR) Methods in the Construction Industry with Special Reference to the Arbitration & Conciliation Act 1996

The construction industry is considered the second largest industry after agriculture. It works purely on a contract basis, based on the Indian Contract Act 1872, with the client on one side and the contractor on the other. The execution of the work and the project is monitored and controlled by qualified Consultants and Engineers. The industry is characterized by its complexity, diversity, and dynamic nature. Disputes in the construction industry are common and can arise from various causes, often leading to delays, cost overruns, and damaged relationships between stakeholders. We have various dispute-resolution methods which will help both parties to amicably solve the disputes.

Expression of p63 and TTF1 in Non-small Cell Lung Carcinoma with Special Reference to Mutation of EGFR and ALK in Adenocarcinoma of the Lung: An Institutional Experience

Expression of p63 and TTF1 in Non-small Cell Lung Carcinoma with Special Reference to Mutation of EGFR and ALK in Adenocarcinoma of the Lung: An Institutional Experience

Ayurveda heals - Virechana for wound healing with special reference to Shareerika (Pittaja) Vrana: A case report

Shareerika Vrana also called as Nija Vrana are said to be result of Doshopaplava (Dosha dushti) and are Kashta Sadhya as compared to Sadyo Vrana. A 43 years old female patient approached outpatient department with chief complaints of a non-healing wound in the both of her feet at the dorsal aspect associated with pain, discharge & burning sensation. On examination it was analyzed as Shareerika (Pittaja) Vrana (non-healing ulcer). Patient was treated with classical Ayurveda therapeutic measures, Shodhana Karma (Virechana Karma), & Ropana Karma (Bahya and Abhyantara), which included daily dressing with Jatyadi Taila along with Triphala guggulu & Gandhaka rasayana internally. A remarkable improvement in the condition of the wound is observed with significant healing during treatment period with complete healing in 7 days post Virechana Karma. In this study, an attempt is made to prove the role of Virechana in Wound Healing with special reference to Shareerika Vrana. Keywords: Shareerika Vrana, Virechana Karma, Shashthi Upakrama, Ropana karma

Role of Takshak in the Transition of Yug: a Critical Commentary (with Special Reference to Khandava Vana Episode)

In Indian belief system, snake is regarded not only an evil creature but also a divinity representing eternity and prosperity as well. On the mythological grounds, they are often associated with Lord Vishnu (He is the preserver of the Universe according to Hindu Mythology), Lord Krishna (He is described as the Supreme Being and creator of the Universe) and Lord Shiva (the third God in the Hindu Trimurti). The Bhāgvat Purāna (deals with all the incarnation Lord Vishnu) mentions several snake deities such as Kadaru or Kadaroo (mother of all snakes, and wife of Kashyap Rishi and Vinta (mother of birds Garuda and Arun, wife of Kashyap Rishi). There are various folklores representing multifaceted facts on Takshak (One of the major Nag or snake, it plays an important role in the Khandava Vana episode) and its deeds. In this backdrop, the present paper aims to explore, discuss and study Takshak’s dilemma, its struggle in Dwāparyug and also its role in the transition of Yugas.

A study of Rural women’s financial literacy and awareness level towards financial products and services in Kerala perspective with Special reference to Malappuram District

Financial literacy is crucial in empowering individuals, particularly rural women, to make informed financial decisions and achieve economic well-being. This study explores the financial literacy and awareness levels of rural women in the Malappuram district, focusing on the relationship between socio-demographic factors and financial literacy. The research, conducted through a cross-sectional descriptive study among 100 women, reveals that most respondents are young, educated, and possess a moderate level of awareness and knowledge of financial tasks and products. The study highlights significant barriers to financial literacy, including social and cultural issues, lack of education, income constraints, and gender discrimination. Despite these challenges, the penetration of financial products like bank accounts, debit cards, and mobile banking is relatively high among the participants. The study finds a significant relationship between age and financial literacy but no significant correlation between education or income levels and financial literacy awareness. The findings underscore the need for targeted financial education programs to enhance financial literacy among rural women, addressing identified barriers and focusing on age-specific strategies to improve their economic participation and contribute to national economic development.

Assessing the Noncovalent Interaction of Deucravacitinib and Ethanol with Special Reference to an Independent Gradient Model Based on Hirshfeld Partition.

The current study begins by optimizing the deucravacitinib molecule in the gas phase at the ωB97XD/cc-pVDZ level of theory using density functional theory and proceeds to study its intramolecular interactions. Further, a molecule of EtOH was introduced at different locations on the deucravacitinib molecule, and the noncovalent interactions arising from them were also investigated using several computational tools. In this way, eight deucravacitinib-EtOH systems (1-8) were identified and their electronic environment was studied after evaluating their binding energy. Using natural bond orbital analysis, the localization of charges between the donor and acceptor fragments in these interacting systems was examined. The nature of interactions was analyzed using the reduced gradient approach (NCI analysis), and few hydrogen bonding interactions (intermolecular and intramolecular) were found in each system. The strength of these hydrogen bonding interactions was further investigated by using theoretical tools such as atoms in molecules analysis and independent gradient model based on Hirshfeld partition analysis. The binding energy of deucravacitinib with EtOH was decomposed into energy components based on the domain-based local pair natural orbital coupled cluster technique using LED analysis. The results from the hydrogen bonding interaction analysis using different computational tools were found to be consistent with the calculated order of binding energy of systems 1-8 and they also pointed toward the higher stability of system 3.

Child leader standing on a precipice: a case study of NextGenInnov8

Learning outcomes After completion of the case study, students will be able to identify the traits required in child leadership and the ability to apply “The Whole Leadership Framework” child leadership model today, identify and discover opportunities to promote child leadership and analyse its sustainable impact and analyse how innovation clubbed with sustainability will create a competitive advantage with special reference to the innovative ultraviolet-C light sterilisation Suraksha Box. Case overview/synopsis Aditya Pachpande was a child prodigy of India, who had stunned the world with his trailblazing attitude ever since the tender age of 12. Aditya’s father, Sandeep Pachpande, a Harvard alumnus, wondered – “My son is ahead of his time. Would institutions ever acknowledge my innovative boy as a child leader? Will my child become a teen chief executive officer (CEO)? Will he ever get accepted?” Aditya leads by example as a student, changemaker, edupreneur, innovator and keynote speaker. He thinks, “Age is just a number”, but has had to shout out loud to be heard. With the nickname “Lecture man” given by his teachers and peers, he went on to contribute in endorsing skill-based experiential and discovery-based teaching-learning that addresses real-world issues and sustainable development goals. A CEO at the age of 11 years, he co-founded NextGenInnov8 Global Solutions Private Limited and NextGenInnov8 Social Foundation. Although achieving these milestones, he had to manoeuvre through several curve balls hurled at him by the system. Not the one to ever compromise on ethics, values and purpose, today he was at the crossroads – whether he should choose social change over-commercialisation of his business, simplicity and minimalism over product perfection, crowdfunding over loans or angel investors, manufacture in China or make in India just to name a few. The unstoppable Aditya, aspiring for acceptance, dreamt that someday, these policymakers and businesses would acknowledge child innovators and not write them off just because they were adolescents. Aditya, standing on a precipice, dreamt along. Complexity academic level This case has been particularly focused on postgraduate-early stage-level students pursuing business or entrepreneurial education-related programs. Supplementary materials Teaching notes are available for educators only. Subject code CSS 3: Entrepreneurship.

Factors Affecting Failure of Rural Entrepreneurs: Special Reference to Teldeniya Divisional Secretariat Area in Kandy District, Sri Lanka

This study aims at identifying factors affecting to failure of rural entrepreneurs and to examine moderate impact of financial literacy over the failure of rural entrepreneurs. This quantitative study investigates rural entrepreneurial failure in Sri Lanka's Teldeniya Divisional Secretarial Area. A sample of 187 entrepreneurs, who experienced failure, was surveyed, focusing on factors like risk aversion, perseverance, and financial literacy as a moderating influence. Objectives included identifying failure contributors and examining financial literacy's moderating impact on rural entrepreneurship. The study highlights key competencies and their relationship with failure, emphasizing financial literacy's role. It contributes valuable insights for governments, development organizations, and rural entrepreneurs to address failure causes and leverage financial literacy for improved outcomes. The findings hold practical applications for enhancing rural entrepreneurship in Teldeniya and similar areas.

Impact of season on phytochemistry with special reference to β-Asarone content, extract yield and Pharmacognostic parameter in rhizome of Acorus calamus L.

Demand of medicinal plants is growing exponentially due to its extensive use in nutraceutical, cosmeceutical and pharmaceutical industries. The major problem is the variation in quality and quantity of phytoconstituents with the collection of medicinal plants in each batch. Though, the quality and quantity of phytoconstituents in plants are influenced by various factors, chief among them is seasonal variation. Rhizome of Acorus calamus L. is used in treatment of neurological disorder specially in children. The Ayurvedic system of medicine believes blends of constituent imparts therapeutic activities. The main chemical constituent responsible for cognition enhancement is Asarone. An attempt has been taken to record change in Pharmacognostic parameter with season and evaluate the best collection time of rhizome of Acaorus calamus L. with special reference to extractive value and asarone content.

Effect of Kshoudradi Aschyotana in Arjuna w.s.r to Sub-Conjunctival Haemorrhage: A Randomised Clinical Trial

Introduction: Subconjunctival haemorrhage (SCH) is a frequent eye condition marked by bleeding beneath the conjunctiva, which causes noticeable discoloration and generally disturbs the affected person. There is currently no specific treatment for SCH in contemporary medical practices. According to Ayurveda, it correlates with Arjuna. It is a rakta pradoshaj vikara (disease caused by vitiated blood) and primarily a pitta-predominant disease manifesting in the Shukla mandala of netra. Objectives: The objective of the study was to compare the efficacy of Kshoudradi Aschyotana with Flurbiprofen Eye Drops in Arjuna with special reference to sub-conjunctival haemorrhage. Materials and Methods: After securing ethical clearance and registering the trial with the CTRI, twenty patients satisfying the inclusion criteria and diagnosed with arjuna were randomised into two groups(10 in each group). The trial group and the control group received Kshoudradi Aschyotana and Flurbiprofen eye drops for 5 days respectively. Objective parameters were assessed using Slit-Lamp photography and the area of the lesions was recorded on the baseline, 5th, and 7th days. The statistical analysis of the area of haemorrhage was conducted using independent and paired t-test for between and within-group analysis respectively. Results: Kshaudraadi Aschyotana has exhibited better results in reducing the area of subconjunctival haemorrhage as compared with flurbiprofen eye drops within five days(P <0.05). Conclusion: The study concludes that Kshaudraadi Aschyotana has beneficial effects in the management of Arjuna as compared with the flurbiprofen eyedrops.

Sustainable Development and Traditional Knowledge with Special Reference to the Bodo Community

Traditional Knowledge of local or indigenous communities are developed and nurtured over many generations. Its wisdom has enabled communities to adapt and interact with their environment. The knowledge system of indigenous communities is embedded in their traditions, customs and practices. In many cases, such knowledge is orally transmitted through folklore, art, customary laws and rituals. Indigenous communities possess a wide array of traditional knowledge developed through the collection of insights of their surroundings and as a response to it. This has allowed them to sustain and reduce risks, thus enabling them to co-exist, utilize and adapt with their surroundings. Traditional knowledge, therefore, forms a vital asset for the indigenous communities such as the Bodos of North-east India. Due to globalization and the development of modern sciences and technology, the traditional knowledge of indigenous societies faces multiple challenges and have witnessed the reduction in its importance. However, the growing emphasis on sustainable development has begun to shed a new light in its direction. This paper, therefore, is an attempt to study the relevance of traditional knowledge in the achievement of sustainable existence of human beings with an emphasis on the Bodos community.