ABSTRACT Palembang has sustained heavy haze pollution events that are related to decrease public health quality. Because ground-based PM2.5 observation in the city has some limitations, such as spatial and temporal coverages. Thus, in this study, we applied the potential of using the surface mass concentration PM2.5 data acquired by the MERRA-2 satellite to predict daytime and night-time PM2.5 levels during heavy haze events in Palembang City. Results of the study revealed that the highest PM2.5 level was about 160 µg/m3 at 02:00 (night-time), while the lowest PM2.5 level was about 50 µg/m3 at 14:00 (daytime). Spatiotemporal variation of PM2.5 over the study area showed that more than half of the area showed PM2.5 above 90 µg/m3 at night. Stable wind conditions (2 m/s) and air temperature (29°C), and relative humidity (74%) in the study area have contributed to particulate matter accumulation. The study concluded that PM2.5 acquired by the MERRA-2 satellite could provide a new reliable source for assessing severe air pollution events.