Soil salinization of the reclaimed tidelands is problematic. Therefore, there is a need to characterize the spatial variability of soil salinity associated with soil moisture and other soil properties across the reclaimed tidelands. One approach is the use of easily-acquired ancillary data as surrogates for the arduous conventional soil sampling. In a reclaimed coastal tideland in the south of Hangzhou Gulf, backscattering coefficient (σ0) from remotely sensed ALOS/PALSAR radar imagery (HH polarization mode) and apparent soil electrical conductivity (ECa) from a proximally sensed EM38 were used to indicate the spatial distribution of soil moisture and salinity, respectively. After that, response surface methodology (RSM) was employed to determine an optimal set of 12 soil samples using spatially referenced σ0 and ECa data. Spatial distributions of three soil chemical properties [i.e. soil organic matter (SOM), available nitrogen (AN), and available potassium (AK)] were predicted using inverse distance weighted method based on the 12 samples and were then compared with the predictions generated using 42 samples obtained from a conventional grid sampling scheme. It was concluded that combination of radar imagery and EM induction data can delineate the spatial variability of two key soil properties (i.e. moisture and salinity) across the study area. Besides, RSM-based sampling using radar imagery and EM induction data was highly effective in characterizing the spatial variability of SOM, AN and AK, compared with the conventional grid sampling. This new approach may be used to assist site specific management in precision agriculture.