The article is devoted to the study of an important component of innovative infrastructure – pilot innovative territorial clusters. The mainstages of their formation wereconsidered,spatial patterns of development,structure and economic efficiency were identified and analyzed. The purpose of the study is to analyze the spatial regularities of pilot innovative territorial clusters functioning to justify the promising directions of the state cluster policy contributing to the effective use of the financial resources of the federal budget by determining priority investment directions and establishing on this basis the recipients of state support in the cluster with the greatest potential in the context of limited financial resources. This is promising primarily for justifying the stimulation of new high-tech industries and enterprises. The study was carried out on the basis of materials from official federal and regional statistics, information and analytical reports of the Association of Clusters, Technoparks and SEZs of Russia, official ratings of regions innovative development, legislative acts of the federal and regional levels. Patterns of functioning and trends in the development of innovative territorial clusters have been identified. The main purpose of the emerging innovative territorial clusters is to saturate the huge domestic market with high-tech goods, services and technologies in order to achieve the country’s technological independence. Promising directions for improving the cluster policy of Russia are formulated.