In this paper, the POI data of 736 Cainiao stations in Nanjing is taken as the research sample. With the help of ArcGIS software, the standard deviation ellipse, spatial autocorrelation, average nearest neighbor, cold and hot spot analysis, nuclear density estimation, and other spatial analysis models are used to quantitatively characterize its business mode, spatial distribution characteristics, and equilibrium. Based on DNN, the spatial agglomeration characteristics and distribution directions of the Cainiao station in Nanjing were sorted out, the cold spots and hot spots of the spatial layout were identified, and the spatial differentiation rules and agglomeration patterns were revealed. Finally, the geographically weighted regression analysis model is used to analyze the influencing factors of the spatial agglomeration of the Cainiao station in Nanjing. The research found that Firstly, the proportion of Nanjing Cainiao station operating mode adopting the exclusive mode is 59.1%, the proportion adopting the concurrent operation mode is 33.7%, and the rest adopting the joint operation mode of cooperation with other logistics enterprises. Secondly, Nanjing Cainiao Station gathers in the central city area, forming a “central hot spot.” The urban fringe area does not form a “peripheral cold spot area,” and the whole presents a “1 + 4” five-core agglomeration model across the river. Thirdly, Regional GDP, population density, and the number of convenience stores/supermarkets are the main factors affecting the spatial agglomeration of the Cainiao station in Nanjing.
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