Less Disease Research Articles

Correlations between Trunk Control and Balance in Children with Bilateral Spastic Cerebral Palsy.

Impairments of postural responses are a salient feature of children with cerebral palsy (CP). While the systems approach describes balance in seven components, the relationship between trunk control and balance in children with CP has not been previously examined with all seven of these components. In this study, we aimed to identify correlations between trunk control and all seven systems approach balance components in children with bilateral spastic CP. Our participants were 30 children (M age = 11.83, SD = 2.32 years) with CP having a Gross Motor Function Classification System level ranging from I to III. We assessed trunk control with the Trunk Control Measurement Scale, including static and dynamic balance (selective voluntary control and reaching). Balance in standing was assessed using Kids-Mini-BESTest involving four domains: anticipatory, reactive, sensory orientation and stability in gait. We used Spearman's rank correlations to correlate trunk control and balance, and we obtained a moderate correlation between the trunk control measurement scale and the Kids-Mini-BESTest in children with both bilateral spastic CP (rs = .618, p < .001) and spastic diplegic CP (rs = .52, p = .02). Analysis of the correlations between separate domains of the Kids-Mini-BESTest and the trunk control measurement scale subscales revealed moderate correlations between the static sitting balance subscale and all four domains of the Kids-Mini-BESTest. The dynamic selective motor control subscale of the trunk control measurement scale moderately correlated with the anticipatory domain of the Kids-Mini-BESTest. The dynamic reaching subscale also correlated moderately with anticipatory and stability in gait domains. This correlation was statistically significant in the 13 to 17-year-old age group and was strong among females, whereas the correlation was moderate in males. Trunk control was moderately associated with balance considering all the systems theory components of balance in children with bilateral spastic cerebral palsy.

Effect of Task Specific Circuit Training on Gait and Functional Mobility among Spastic Diplegic Cerebral Palsy

Background and Need for the Study: Spastic diplegic cerebral palsy is the most prevalent and common formof the cerebral palsy. Gait, balance, and coordination are all negatively impacted because it mostly affects thebilateral lower extremities.Purpose of the Study: The purpose of the research was to find out the effectiveness of task specific circuit trainingon gait and functional mobility in children with spastic diplegic cerebral palsy.Methods: In this research, selected 30 children according to inclusion and exclusion criteria. All the Childrenparticipating in the study were separated into two groups, Task specific circuit training group and Conventionalgroup, children’s parents were explained about the safety and procedure. Inform assent was provided to thechildren’s parents after explaining about the intervention and study procedure.Results: Pre-test measurements and Post-test measurements of the gait and functional independence, assessedusing the Edinburgh visual gait scale (EVGS) and GMFM-88. Paired t-test and unpaired t-tests were used forcalculating the mean and standard deviation.Conclusion: The research eventually reached the conclusion that task-specific circuit training is an efficient methodfor improving gait and functional mobility when used in conjunction with regular physiotherapy.

Effectiveness of Spider Cage Therapy for Balance Control in Spastic Diplegic Cerebral Children: A Pilot Study

Background: Spastic diplegic cerebral palsy (CP), a neurological disorder that specifically affects the lowerextremities, affects mobility and posture. People with spastic diplegia frequently have balance problems, whichreduces their functional independence and raises their risk of falling. In order to treat balance impairments in thispopulation.Purpose: The aim of the study is to examine novel and alternative treatment approaches that may possibly enhancethe motor function and general quality of life in spastic diplegic cerebral palsy children by examining the efficacyof spider cage therapy for balance control.Methods: 10 children with spastic diplegic cerebral palsy were allocated into developmental and experimentalgroup. The experimental group (n=5) received spider cage therapy and the developmental group (n=5) receivedconventional physiotherapy.Result: This finding shows that the conventional group pre and post-test values by using GMFM (30.2±1.67,34.95±1.58) experimental group pre &amp; post value of GMFM (30.55±5.63,36.95±1.64) with p value&lt;0.0001.Conventional group pre &amp; post-test values by using PBS (9.2±3.11,14.95±4.52) and experimental group pre andpost-test values of PBS (9.75±1.58,16.7±1.78) with a p value &lt;0.0001.Conclusion: The study’s findings suggest that children with spastic diplegia might benefit from balance trainingin a spider cage.

Comparison of Percutaneous Versus Open Hamstring Lengthening in Patients of Spastic Diplegic Cerebral Palsy - A Randomized Controlled Trial.

Cerebral palsy (CP) often manifests with crouch gait due to hamstring spasticity, necessitating surgical intervention like hamstring lengthening surgery. Percutaneous techniques are emerging as an alternative to traditional open approaches in orthopedic surgeries. This randomized controlled trial aimed to compare the outcomes of percutaneous hamstring lengthening (pHSL) versus open hamstring lengthening (oHSL) in pediatric patients with spastic diplegic CP, focusing on improvements in gait and knee function. One hundred children diagnosed with spastic diplegic CP were randomized into pHSL (n = 50) and oHSL (n = 50) groups. Surgical procedures were performed using single-event multilevel surgery techniques. Pre-operative and post-operative assessments included range of motion, popliteal angle, gross motor function classification system (GMFCS) score, and gait analysis (functional independence measure [FIM], observational gait scale [OGS], physician gait scale). Statistical analyses were conducted using Statistical Packages for the Social Sciences v25. Both pHSL and oHSL groups showed significant improvements in popliteal angle and GMFCS scores postoperatively (P < 0.001 within each group). However, there were no significant differences between the groups in terms of these outcomes (P > 0.05). FIM, OGS, and physician gait scale also showed comparable improvements between groups (P > 0.05). pHSL is as effective as oHSL in improving gait and knee function in pediatric patients with spastic diplegic CP. The percutaneous approach offers a safe and efficient alternative to traditional open surgery, potentially minimizing muscle damage and promoting quicker recovery.

Association Between Calf Muscle Tone, Plantar Surface Area, and Gross Motor Function in Children with Spastic Diplegic Cerebral Palsy.

Children diagnosed with spastic diplegic Cerebral Palsy (CP) usually demonstrate hypertonicity of the lower limb muscles which affects the normal alignments and weight reception by the feet. These impairments could be correlated to the limitations in gross motor function such as standing and walking abilities. Understanding these relationships can contribute to developing more effective rehabilitation strategies and improving overall motor outcomes for affected children. The current study was designed to explore the relationship between plantar surface area, weight distribution on the plantar surface, and gross motor function (namely, standing and walking abilities) in spastic diplegic CP children. Seventy-one spastic diplegic CP children aged 8-14 years joined this cross-sectional study. The Person's correlation coefficient and regression tests were used to assess the correlation between variables, namely, Gross Motor Function (GMFM), Calf Muscle Tone, Plantar surface area (PSA), and Peak pressure on mid and hind feet (PPMF, PPHF, respectively). These variables were assessed using the GMFM-88 scale, Modified Ashworth scale, and foot scan plantar pressure detection system, respectively. The correlation analysis demonstrated a strong to moderate positive correlation between PSA, PPMF, PPHF, and GMFM-D and GMFM-E. Additionally, regression model showed prediction levels equal to 0.791 for the GMFM-D and 0.720 for the GMFM-E categories, respectively. Standing and walking abilities were positively correlated (r ≥.6) with the increased plantar surface area and higher peak pressure on mid and hind feet in spastic diplegic CP. Future longitudinal studies should investigate changes in gross motor function in relation to improvement in plantar surface area and peak pressure values.

Immediate Effect of a Comprehensive Foot Mobility and Strengthening Treatment on Ankle Muscle Activation in Children with Spastic Diplegia

Foot mobility and strengthening treatment (FMST) is a routinely practiced management strategy in musculoskeletal rehabilitation to improve ankle and foot alignment and muscle function, which prevents joint deformities. The FMST may contribute to improvements in foot alignment and muscle function in children with cerebral palsy (CP). However, treatment influence on muscle imbalances and strength in children with spastic diplegic CP is not yet documented. The aim of the study was to determine the effect of FMST on tibialis anterior (TA), medial gastrocnemius (MG), peroneus longus (PL), and soleus muscle activity using electromyography (EMG) in children with spastic diplegic CP. Twenty children with spastic diplegia (mean age: 7.4 years) with GMFCS levels I, II and III were included in this pre and post-experimental (preliminary) study. Muscle activation of TA, MG, PL, and soleus was recorded using surface EMG in a standing position before and after providing the intervention. Muscle activation in RMS-EMG (mV) was calculated. Findings showed a significant increase in muscle activation of TA, MG, and PL in standing position following the intervention. The increase in soleus muscle activation in standing was not statistically significant. We hypothesized that FMST could alter the muscle recruitment pattern. Our findings showed immediate improvement in muscle activation after the intervention. Future studies should consider its carryover effect on motor performance and gait using functional outcomes.

Effect of Backward Treadmill Training Versus Conventional Therapies to Improve Functional Mobility in Children with Spastic Diplegic Cerebral Palsy

Effect of Backward Treadmill Training Versus Conventional Therapies to Improve Functional Mobility in Children with Spastic Diplegic Cerebral Palsy

Effect of the Dynamic Orthotic Garment on Postural Control, and Endurance in Children with Spastic Diplegic Cerebral Palsy: A Randomized Controlled Trial.

To investigate the effect of dynamic orthotic garments (Thera togs) on foot pressure distribution, postural control, and endurance in children with spastic diplegic CP. This is a single-blind randomized controlled clinical trial involving 34 (8-10 years) with spastic diplegic CP. The control group received conventional physical therapy (CPT), whereas the study group received CPT in addition to wearing TheraTogs. We recorded foot pressure distribution, trunk control measurement scale, trunk position sense, Pediatric Berg Balance Scale (PBS), and six-minute walking distance (6MWD). Both groups showed improvement. The study group had significant improvement in foot pressure distribution (p-value 0.003, 0.001, <0.001 for forefoot, midfoot, and rearfoot mean pressures respectively, and 0.005, <0.001, and 0.005 for forefoot, midfoot, and rearfoot peak pressures respectively), Pediatric balance scale, The trunk control measurement scale, and Trunk position sense (p-value < 0.001) and six-minute walking distance (p-value 0.029). Our data suggest that adding TheraTogs to conventional physiotherapy improves foot pressure, postural control, and endurance in children with spastic diplegic cerebral palsy. Both TheraTogs and conventional physical therapy corrected foot pressure distribution, trunk control, improved balance, and increased 6MWD in children with spastic diplegic CP but the improvement was more significant in TheraTogs group. NCT05271149.

The Effects of Family Functioning on Gross Motor Function, Activity, and Participation in Children with Cerebral Palsy.

The present study aimed to investigate whether family functioning (FF) could impact gross motor function, activity, and participation in children with cerebral palsy (CP). Sixty-seven children with spastic diplegic CP who were admitted to the Special Education and Rehabilitation Clinic were included in the study. The guidelines of the American Academy of Neurology were followed for the diagnosis of spastic diplegia. The type of home where the family lives, the family's average income, the child's age, gender, and number of siblings, and the age and educational level of the child's primary caregiver were recorded. The gross motor function capacity of children with CP was assessed with the Gross Motor Function Classification System (GMFCS). The Pediatric Evaluation of Disability Inventory (PEDI) was used to evaluate activity and participation performance. The children living in detached houses had statistically higher PEDI mobility levels than those living in apartments (p < 0.05). PEDI's social function and self-care levels were higher in 12 to 18-year-old children with two siblings (p < 0.05). The age and educational status of the primary caregiver were found to have an important impact on the PEDI scores. According to the results, social function and self-care levels were higher in children whose primary caregivers were 30 to 65 years old and had high levels of education above high school (p < 0.05 The effects of family income and gender on PEDI scores were statistically non-significant (p˃ 0.05). Variables related to family functioning had no statistically significant effect on GMFCS scores (p˃ 0.05). These factors can enable healthcare providers to collaborate with the families to develop more comprehensive intervention plans emphasizing family strengths and supporting their needs.

Підготовка майбутніх фізичних терапевтів до складання програми фізичної терапії для дітей середнього шкільного віку з хворобою Літтла

The article revealed the issue of professional training of future physical therapists for the preparation of a physical therapy program for middle school children with Little's disease, where it was taken into account that each patient had an individual physical therapy program according to the patient's categorical profile of the ICF, selected research methods and determined physical therapy methods. The purpose of the study was to analyze the preparation for the development of a program of physical therapy for children of secondary school age with Little's disease, which future physical therapists will be able to use in their professional activities. The physical therapy program was developed for a boy, 11 years old, who has the main diagnosis: Little's disease, concomitant diseases: mild mental retardation, valgus deformity of the lower limbs, congenital. A categorical profile was determined according to the short basic set of ICF DP for a child of middle school age (11 years) with Little's disease (spastic diplegia). The physical therapy program included the following methods: therapeutic exercises, mobility training and walking with aids, massage, training on an exercise bike and a home program (fitball exercises to relax muscles, improve balance, gymnastic exercises to increase muscle strength of the upper limbs, improving posture, exercises to improve the mobility of the joints of the lower extremities, strengthening the skills of standing and walking with a walker, games and gymnastics for the fingers (development of the manipulative function of the hands), treatment of position). The study showed that in order to draw up a physical therapy program for patients with Little's disease, it is necessary to determine the research methods, obtain the initial data based on them, compile a categorical profile of the patient according to the ICF, and choose physical therapy methods and their dosage according to the obtained results.

Outcome of delayed versus immediate casting on spasticity of lower limb muscles in cerebral palsy post-botulinum toxin injection

Background: Botulinum toxin type A (BTX-A) is widely used to treat spasticity in children. The optimal strategy for the combined treatment of casting and BTX-A injections is not known. This prospective study is conducted to know the functional outcome of immediate versus delayed casting post-BTX-A injection in children with cerebral palsy (CP). Aims and Objectives: The aim of this study is to compare delayed versus immediate casting as an adjunct to botulinum toxin therapy for spasticity of lower limb muscles in CP. The objectives of the study are to test the hypothesis that delayed casting is superior to immediate casting post-botulinum toxin injection and to know the feasibility of using the Edinburgh visual gait score (EVGS) as a single qualitative and quantitative outcome measure. Materials and Methods: A prospective study is conducted to compare immediate casting with delayed casting post-botulinum toxin injection to spastic lower limb muscles in patients with CP from July 2018 to February 2019. Inclusion criteria: A diagnosis of CP with associated spastic monoplegia, diplegia, or hemiplegia with aided or unaided ambulation. Exclusion criteria: History of orthopedic surgery in the preceding 12 months; selective dorsal rhizotomy; mixed CP; ataxia; athetosis; non-ambulatory subjects. Results: The botulinum toxin injection + delayed POP casting group fared better in terms of clinical and functional outcome (as shown by improved EVGS scores) in our study. Conclusion: There is a clear benefit in delaying casting after the injection of Botulinum toxin in the recurrence of spasticity.

Efficacy of TheraTogs on Biomechanical Variables in Spastic Diplegic Cerebral Palsy Children: A Literature Review

Efficacy of TheraTogs on Biomechanical Variables in Spastic Diplegic Cerebral Palsy Children: A Literature Review

Selective dorsal rhizotomy using a 3D high definition exoscope.

Selective dorsal rhizotomy (SDR) is an established neurosurgical technique for children with spastic diplegia secondary to cerebral palsy. Meticulous intraoperative testing of individual nerve roots with electromyography in tandem with the on-site neurorehabilitation team is recommended for good clinical outcomes. The standard approach requires the neurosurgeons to spend extended time under the traditional operating microscope. In this video, the authors describe the use of a 3D exoscope system for SDR. Overall, the 3D exoscope improves ergonomics and reduces musculoskeletal fatigue for the operating neurosurgeons. Furthermore, it provides excellent visualization of important structures, allowing safe and efficient completion of the procedure. The video can be found here: https://stream.cadmore.media/r10.3171/2023.10.FOCVID23105.

Association Between Gross Motor Function and Manual Ability in Children with Spastic Cerebral Palsy

Background: Cerebral Palsy (CP) is a complex neurological condition that significantly impacts a child's motor abilities. Understanding the relationship between gross motor function and manual ability in children with CP, particularly spastic diplegia, is crucial for developing effective treatment strategies. Objective: This study aimed to investigate the association between Gross Motor Function Classification System (GMFCS) levels and Manual Ability Classification System (MACS) as well as Bimanual Fine Motor Function (BFMF) in children with spastic diplegic CP. Methods: A cross-sectional study was conducted involving 186 children aged 6-12 years with Diplegic CP, using convenience sampling. The GMFCS, MACS, and BFMF were employed to assess gross motor function, manual ability, and bimanual fine motor function, respectively. Data analysis was performed using SPSS 26.0, focusing on descriptive statistics and correlation coefficients. Results: The mean age of participants was 8.35 years (SD = 1.998). The study comprised 57% male and 43% female participants. GMFCS levels distribution showed that the most common level was IV (31.2%), followed by levels III (19.4%) and V (18.8%). A strong correlation was observed between GMFCS and MACS (r = .752, p &lt; 0.001) and a moderate to strong correlation between GMFCS and BFMF (r = .618, p &lt; 0.001). Conclusion: The study concluded that gross motor function significantly influences manual ability in children with spastic diplegic CP. Higher GMFCS levels were associated with more severe impairments in manual ability and bimanual fine motor function.

Effects of routine physical therapy with and without kinesio taping in improving gross motor function in sitting and standing in spastic diplegic cerebral palsy children

ObjectiveTo determine the effectiveness of Kinesio taping along with routine physical therapy on improving gross motor function in sitting and standing among spastic diplegic Cerebral Palsy children. DesignRandomized controlled trial. SettingsUniversity Teaching Hospital University of Lahore, Lahore. Participants53 participants with diagnosed spastic diplegic cerebral palsy were randomly allocated in control and experimental groups. Intervention26 Participants were treated by kinesio taping which was applied in a criss-cross manner along with routine physical therapy program while the control group (n = 27) received NDT exercise program that comprises of stretching, functional reaching, weight-bearing exercises and walking. Outcome measureGross motor function was assessed using 2 components of Gross Motor Function Classification System (GMFCS-88), i.e., sitting as well as standing at the base line and after every 3rd week for 12 weeks follow up. ResultsIn study and control group the mean score of gross motor function for sitting at baseline was 33.96 ± 3.11 and 31.50 ± 3.32 respectively. After intervention, it changed to 47.70 ± 5.46 and 43.46 ± 1.81 respectively. Mean score for Gross Motor Function calculated at base line in study and control group for standing was 27.37 ± 1.14 and 26 ± 3.01 respectively. At the end of intervention, the score improved to 36.55 ± 4.27 and 33.69 ± 2.46 respectively. ConclusionIn comparison to control group, significant increase in gross motor function of intervention group was seen after the 12 weeks of intervention. In this way, over back muscles the application of kinesio tape in a Criss-Cross manner may be helpful. Also it can be used as an additional approach along with routine physical therapy to improve standing and sitting in spastic diplegic children.

Comparison of outcomes following surgical intervention and inpatient rehabilitation stays in children with cerebral palsy.

Literature is limited on functional outcomes in children with cerebral palsy (CP) following surgical procedures and a subsequent inpatient rehabilitation unit (IRU) stay. To compare functional outcomes and length of stay (LOS) in children with CP following a surgical procedure and IRU stay based on the surgical procedure performed, pattern of involvement, etiology, and Gross Motor Function Classification System (GMFCS) level. Retrospective cohort study. Tertiary care pediatrics. Pediatric patients with CP who underwent one of three surgical procedures followed by an IRU stay. Selective dorsal rhizotomy (SDR), single-event multilevel orthopedic surgery (SEMLS), or intrathecal baclofen (ITB) pump implantation and subsequent IRU stay. IRU LOS, Functional Independence Measure for Children (WeeFIM) total score, sub-scores, and efficiency. Children undergoing SDR had a longer LOS (p ≤ .015). Children with spastic diplegia, GMFCS level II, and prematurity-based CP had higher WeeFIM efficiency scores (p ≤ .046, ≤.021, and .034 respectively). Greater changes in WeeFIM™ scores were associated with spastic diplegia, SDR, GMFCS level II, longer LOS, and higher admission scores (p ≤ .045). Although statistically and functionally significant improvements in children with CP following surgical interventions and an IRU stay were seen, those with higher WeeFIM change scores tended to have spastic diplegia, to have undergone SDR, GMFCS level II, longer LOS, and higher admission scores.

Evaluation of Hearing Status in Various Type of Cerebral Palsy Children in a Tertiary Hospital

Background: Cerebral palsy (CP) in children are frequently associated with sensorineural pathology.&#x0D; Objectives: To assess the severity of hearing impairment in children with CP and correlate the auditory impairment with different types of CP.&#x0D; Materials &amp; Methods: This cross-sectional study was conducted in the Department of Pediatric neurology and Autolaryngiology- Head and Neck Surgery BSMMU, during March to September 2011. Diagnosed CP patients were included consecutively. After taking informed written consent, proper history and clinical examinations was done and severity of hearing loss was assessed.&#x0D; Results: Among the 50 children with CP, Tympanometry result revealed that negative middle ear pressure was present in 32% in spastic quadriplegia(SQ), 24% in spastic hemiplegia (SH), 16% in spastic diplegia (SD) and 24% in mixed type. Eustachian tube dysfunction was present in 62.5% in spastic hemiplegia. In TOAE result 52% were pass and 48% were referred and ABR were suggested. On the basis of result of TOAE, those were referred, initially they were encountered as hearing impairment in this study. Among them, in SQ were 18%, SH were 12% and mixed. Follow up auditory brain stem response revealed mild, moderate and severe sensorineural hearing loss were 8% in spastic quadriplegic type and the spastic diplegia and athetoid group were 2% only mild, Moderate sensorineural hearing were 2% in spastic hemiplegia group.&#x0D; Conclusion: Spastic Quadriplegic cerebral palsy patients had the maximum incidence of hearing impairment. Perinatal asphyxia and prematurity were the main risk factor of hearing impairment.&#x0D; BANGLADESH J CHILD HEALTH 2022; VOL 46 (1) : 19-22

Functional outcome after selective dorsal rhizotomy: a retrospective case control study.

This study examines long-term benefit on functional outcomes and quality of life after selective dorsal rhizotomy (SDR) in children with spastic diplegia in Hong Kong. This is a case control study. Individuals with spastic diplegia who were at 6 to 12years post-SDR were recruited. Age, gender, cognition, and Gross Motor Function Classification System level-matched individuals with spastic diplegia who had not undergone SDR were recruited as controls. Outcome measures included physical level, functional level, physiological level, and quality of life. All data were compared by independent t-test. Individuals post-SDR (n = 15) demonstrated a significantly better range of ankle dorsiflexion in knee extension by - 5.7 ± 10.9° than the control group (n = 12). No other significant differences were observed. SDR is a safe, one-off procedure and provides long-term reduction in spasticity with no major complications. With the heterogeneity, we did not demonstrate between-group differences in long-term functional outcomes.

Symptomatic spinal arachnoid cyst with spastic diplegia secondary to cerebral palsy: illustrative case

BACKGROUND Selective dorsal rhizotomy (SDR) can improve the spastic gait of carefully selected patients with cerebral palsy. Spinal arachnoid cysts are a rare pathology that can also cause spastic gait secondary to spinal cord compression. OBSERVATIONS The authors present an interesting case of a child with cerebral palsy and spastic diplegia. He was evaluated by a multidisciplinary team and determined to be a good candidate for SDR. Preoperative evaluation included magnetic resonance imaging (MRI) of the spine, which identified an arachnoid cyst causing spinal cord compression. The cyst was surgically fenestrated, which provided some gait improvement. After recovering from cyst fenestration surgery, the patient underwent SDR providing further gait improvement. LESSONS SDR can be beneficial for some patients with spastic diplegia. Most guidelines do not include spinal MRI in the preoperative evaluation for SDR. However, spinal MRI can be beneficial for surgical planning by localizing the level of the conus. It may also identify additional spinal pathology that is contributing to the patient’s spasticity. In rare cases, such as this one, patients may benefit from staged surgery to address structural causes of spastic gait prior to proceeding with SDR.

Functional connectivity of sensorimotor network is enhanced in spastic diplegic cerebral palsy: A multimodal study using fMRI and MEG

ObjectiveTo assess the effects to functional connectivity (FC) caused by lesions related to spastic diplegic cerebral palsy (CP) in children and adolescents using multiple imaging modalities. MethodsWe used resting state magnetoencephalography (MEG) envelope signals in alpha, beta and gamma ranges and resting state functional magnetic resonance imaging (fMRI) signals to quantify FC between selected sensorimotor regions of interest (ROIs) in 11 adolescents with spastic diplegic cerebral palsy and 24 typically developing controls. Motor performance of the hands was quantified with gross motor, fine motor and kinesthesia tests. ResultsIn fMRI, participants with CP showed enhanced FC within posterior parietal regions; in MEG, they showed enhanced interhemispheric FC between sensorimotor regions and posterior parietal regions both in alpha and lower beta bands. There was a correlation between the kinesthesia score and fronto-parietal connectivity in the control population. ConclusionsCP is associated with enhanced FC in sensorimotor network. This difference is not correlated with hand coordination performance. The effect of the lesion is likely not fully captured by temporal correlation of ROI signals. SignificanceBrain lesions can show as increased temporal correlation of activity between remote brain areas. We suggest this effect is likely separate from typical physiological correlates of functional connectivity.