Driving the numerous elements of 2D matrix arrays for 3D ultrasound imaging is very challenging in terms of cable size, wiring and data rate. The sparse array approach tackles this problem by optimally distributing a reduced number of elements over a 2D aperture while preserving a decent image quality and beam steering capabilities. Unfortunately, reducing the number of elements significantly reduces the active probe footprint reducing as a consequence the sensitivity and at the end the signal-to-noise ratio. Here we propose a new coded excitation scheme based on complete complementary codes to increase the signal-to-noise ratio in 3D ultrasound imaging with sparse arrays. These codes are known for their ideal auto-correlation and cross-correlation properties and have been widely used in Code-Division Multiple Access systems (CDMA). An algorithm for generating such codes is presented as well as the adopted imaging sequence. The proposed method has been compared in simulations to other coded excitation schemes and showed significant increase in the signal-to-noise ratio of sparse arrays with no correlation artifacts and no frame rate reduction. The gain in signal-to-noise ratio compared to the case where no coded excitation is used was around [Formula: see text] and the contrast was also improved by [Formula: see text] while the resolution was unchanged.
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