Significant progress has been made recently with the contribution of technological advances in studies on brain cancer. Regarding this, identifying and correctly classifying tumors is a crucial task in the field of medical imaging. The disease-related tumor classification problem, on which deep learning technologies have also become a focus, is very important in the diagnosis and treatment of the disease. The use of deep learning models has shown promising results in recent years. However, the sparsity of ground truth data in medical imaging or inconsistent data sources poses a significant challenge for training these models. The utilization of StyleGANv2-ADA is proposed in this paper for augmenting brain MRI slices to enhance the performance of deep learning models. Specifically, augmentation is applied solely to the training data to prevent any potential leakage. The StyleGanv2-ADA model is trained with the Gazi Brains 2020, BRaTS 2021, and Br35h datasets using the researchers’ default settings. The effectiveness of the proposed method is demonstrated on datasets for brain tumor classification, resulting in a notable improvement in the overall accuracy of the model for brain tumor classification on all the Gazi Brains 2020, BraTS 2021, and Br35h datasets. Importantly, the utilization of StyleGANv2-ADA on the Gazi Brains 2020 Dataset represents a novel experiment in the literature. The results show that the augmentation with StyleGAN can help overcome the challenges of working with medical data and the sparsity of ground truth data. Data augmentation employing the StyleGANv2-ADA GAN model yielded the highest overall accuracy for brain tumor classification on the BraTS 2021 and Gazi Brains 2020 datasets, together with the BR35H dataset, achieving 75.18%, 99.36%, and 98.99% on the EfficientNetV2S models, respectively. This study emphasizes the potency of GANs for augmenting medical imaging datasets, particularly in brain tumor classification, showcasing a notable increase in overall accuracy through the integration of synthetic GAN data on the used datasets.
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