To solve the power limitation problem faced by the development of EPS system for commercial vehicles and achieve the high-performance steering, this article presents a novel dual power-driven electric power steering system (DPEPS) for commercial vehicles by using the open winding permanent magnet synchronous motor (OPMSM) fed by dual inverter with high and low DC voltage supplies. First, the two-level control strategy is introduced for the developed DPEPS system, where the upper control is designed to make the actual steering follow the expected steering performance as determined by the assistant torque curve and to generate the appropriate target current according to the vehicle speed and steering torque. And then the lower control consists of the synthetical space vector control scheme and dual PI control loop is used to execute commands from the upper control, which can make the motor execute the appropriate power supply method according to the steering torque and assist current. Finally, a co-simulation model is carried out for an electric bus, and based on which the proposed DPEPS system is validated.