Soymida Febrifuga Research Articles

Evaluation of antioxidant and antimicrobial properties of Soymida febrifuga leaf extracts

The present study was designed to evaluate the antioxidant and antimicrobial properties of hexane (LH), methanol (LM) and aqueous (LA) extracts of Soymida febrifuga (Maliaceae) leaves, which is a traditional folk medicine in India. No pharmacological evaluation of this plant (except antiplasmodial activity) has been reported to date. Antioxidant activity of different extracts was evaluated by DPPH free radical scavenging activity, taking total phenolic content (TPC) as an index. Antimicrobial activity was tested against six bacterial and five fungal strains using the agar hole diffusion method and the minimum inhibitory concentrations (MIC) and minimum microbicidal concentration (MMC) were determined for all the test organisms against the extracts. The results showed that the methanol and aqueous extracts of leaf had a higher antioxidant activity and total phenolic content than the hexane extract. The antioxidant activity and TPC of the extracts were highly correlated. Extracts also showed several degrees of antimicrobial activity against different microbes. The methanol extract was more potent against Aspergillus fumigatus and Candida tropicana. The lowest MIC values obtained for LM, LA and LH were 78, 156, 625 microg/mL against A. fumigatus, C. tropicana and C. albicans, respectively. Hence, this study confirms that Soymida febrifuga leaves possess potent antioxidant and antimicrobial activity.

Phytochemical and Antimicrobial Studies of Methyl Angolensate and Luteolin-7-O-glucoside Isolated from Callus Cultures of Soymida febrifuga

Soymida febrifuga (Roxb.) A. Juss. is an indigenous lofty deciduous medicinal tree, monotypic genus endemic to India. Hexane, ethyl acetate and methanol extracts of Soymida febrifuga root callus were tested for their phytochemical constituents and antimicrobial activity. Among them, ethyl acetate extract was found to be most effective, which on subjection to silica gel column chromatography led to the separation and isolation of methyl angolensate and luteolin-7-O-glucoside. Structures were determined by Nuclear Magnetic Resonance and Liquid Chromatographic Mass Spectroscopic methods. Further studies indicated that methyl angolensate and luteolin-7-O-glucoside had an anti-bacterial effect against Bacillus subtilis and Salmonella typhimurium, respectively. In addition to that methyl angolensate had an anti-fungal activity against Aspergillus niger while luteolin-7-O-glucoside inhibited Alternaria alternata.

Microwave- and ultrasound-assisted oxidation of bio-active limonoids

Tetranortriterpenoids from Azadirachta indica A. Juss and Soymida febrifuga (Meliaceae), have been selectively oxidized to single major products which exhibit bioactivity higher than the parent compounds, comparable to that of azadirachtin A. The reaction proceeds to completion in less than 15 min and 1 min on being assisted by ultrasound and microwave irradiation, respectively.

In vitro screening of Indian medicinal plants for antiplasmodial activity

Plants traditionally used in India to treat fever or malaria were examined in vitro for antiplasmodial properties against Plasmodium falciparum. Of 80 analysed ethanol extracts, from 47 species, significant effects were found for 31 of the extracts. These represent 23 different species from 20 families. Of the active species 20 were tested against P. falciparum for the first time. The following five species seems to be of special interest for further antimalarial studies, Casearia elliptica, Holarrhena pubescens, Pongamia pinnata, Soymida febrifuga, and Plumbago zeylanica.

Pollen analysis of rock bee summer honeys from the Prakasam district of the Andhra Pradesh, India

SUMMARYThe paper deals with the pollen analysis of six squeezed honey samples collected from rock bee (Apis dorsata) combs during the period 1982–1984. All the samples represented summer honeys from tropical dry deciduous forest tracts of the Prakasam district of Andhra Pradesh, India. The samples, which were all multifloral, contained a total of 57 pollen types. The results indicate that Cassia fistula, Terminalia alata, Bauhinia racemosa, Feronia elephantum, Lagerstroemia parviflora, Strychnos potatorum, Zizyphus xylopyrus, Phyllanthus sp., Soymida febrifuga, Syzygium cumini, Dalbergia latifolia and Caesalpinia bonduc constitute fairly reliable nectar sources for honey bees in this area during the summer.

Morphological studies in Meliaceae. II. A reinvestigation of floral anatomy of members of Swietenieae and Trichilieae

The floral anatomy ofSwietenia mahogoni Jacq.,Soymida febrifuga Juss.,Chukrassia valutino A. Juss.,Dysoxylum binectariferum Hook.,Aphanamixis rohituka W. & A. andHeynea trijuga Roxb. are discussed. Calyx is supplied by two whorls of traces inSwietenia, Aphanamixis, Chukrassia andHeynea and only one whorl of traces inSoymida andDysoxylum. In all the species, exceptHeynea, petals receive their supply independently. InHeynea petals receive their supply from compound strands. Staminal tube receives its supply from compound strands inSwietenia,Chukrassia, Heynea, Aphanamixis and from independent strands inSoymida andDysoxylum. Anthers are syngenesious inDysoxylum.

Tetranortriterpenoids and related substances. Part 18. Two new tetranortriterpenoids with a modified furan ring from the bark of Soymida febrifuga A. Juss (Meliaceae)

Two new tetranortriterpenoids from the bark of Soymida febrifuga A. Juss (Meliaceae) have been assigned structures (3) and (5). Both compounds have a β-substituted γ-methoxybutenolide in place of the usual β-substituted furan system.