AbstractForeshocks can provide valuable information about possible nucleation process of a mainshock. However, their physical mechanisms are still under debate. In this study, we present a comprehensive analysis of the earthquake sequence preceding the 2010 Mw7.2 El Mayor‐Cucapah mainshock, including waveform detection of missing smaller events, relative relocation, and source parameter analysis. Based on a template matching method, we find a tenfold increase in the number of earthquakes than reported in the Southern California Seismic Network catalog. The entire sequence exhibits nearly continuous episodes of foreshocks that can be loosely separated into two active clusters. Relocated foreshocks show several seismicity streaks at depth, with a consistently active cluster at depths between 14 and 16 km where the mainshock was nucleated. Stress drop measurements from a spectral ratio approach based on empirical Green's functions show a range between 3.8 and 41.7 MPa with a median of 13.0 MPa and no clear temporal variations. The relocation results, together with the source patches estimated from earthquake corner frequencies, revealed a migration front toward the mainshock hypocenter within last 8 hr and a chain of active burst immediately 6 min prior to the mainshock. Our results support combined effects of aseismic slip and cascading failure on the evolution of foreshocks.