We present new results on existence and uniqueness of absolutely continuous solutions for systems of discontinuous ordinary differential equations. Our existence result complements an earlier theorem by Bressan and Shen. Basically, we show that a global transversality condition assumed by Bressan and Shen need only be imposed on the sets where the nonlinear part is discontinuous. Our proof, completely different to the one given by Bressan and Shen, uses Krasovskij solutions as a first step. We illustrate the applicability of our result with several examples not covered by the previous literature. The second part of this paper concerns uniqueness. Specifically, we prove uniqueness of solutions for discontinuous systems of differential equations with piecewise Lipschitz continuous nonlinearities and assuming localized Bressan–Shen transversality conditions on the boundaries between different Lipschitz continuity domains. Our uniqueness result appears to be new even in the classical case of continuous nonlinearities.