This article explores the relationship between forest cover and coronavirus disease 2019 (COVID-19) cases in Colombia using remote sensing techniques and data analysis. The study focuses on the CORINE land cover methodology's five main land cover categories: artificial territory, agricultural territories, forests and semi-natural areas, humid areas, and water surfaces. The research methodology involves several phases of the unified method of analytical solutions for data mining (ASUM-DM). Data on COVID-19 cases and forest cover are collected from the Colombian National Institute of Health and Advanced Land Observation Satellite (ALOS PALSAR), respectively. Land cover data is processed using QGIS software. The results indicate an inverse relationship between forest cover and COVID-19 cases, as evidenced by Pearson's index ρ of -0.439 (p-value <0.012). In addition, a negative correlation is observed between case density and forests and semi-natural areas, one of the land cover categories. The findings of this study suggest that higher forest cover is associated with lower numbers of COVID-19 cases in Colombia. The results could potentially inform government organizations and policymakers in implementing strategies and policies for forest conservation and the inclusion of green areas in densely populated urban areas.