Solution Temperature Research Articles

Antidehydration and Stable Mechanical Properties during the Phase Transition of the PNIPAM-Based Hydrogel for Body-Temperature-Monitoring Sensors.

Poly(N-isopropylacrylamide) (PNIPAM) enhances the reversibility and responsiveness of wearable temperature-sensitive devices. However, an open question is whether and how the hydrogel design can prevent adhesive performance loss caused by phase-transition-induced dehydration and unstable mechanical properties between devices and human skin and reduce interfacial failure. Herein, a gelatin-mesh scaffold-based hydrogel (NAGP-Gel) is constructed to inhibit dehydration and volume change, leading to stable mechanical properties, superior adhesiveness, and thermal sensing sensitivity during the phase transition. NAGP-Gel enhances the polymer chains-water interaction and weakens the degree of aggregation of polymer chains-chains, improving antidehydration properties under 45 °C conditions that are higher than the lower critical solution temperature (LCST; i.e., ∼32 °C). The mesh scaffold greatly restricts the phase-transition-induced polymer chain movement and maintains the mechanical performance. In a 60 °C environment, the maximum water loss and volume retention ratio of NAGP-Gel are only 3.58% and 97.3%, respectively. Additionally, NAGP-Gel serves as a temperature sensor, producing a stable thermal-electrical signal within the LCST range. It also can be assembled into an electronic device enabling the transmission of information and recognition of sign language via Morse code. This work broadens the application of PNIPAM in constructing intelligent hydrogels and opens the door to exploring emerging hydrogels for temperature-monitoring applications.

Structural Analysis of the 20S Proteasome Using Native Mass Spectrometry and Ultraviolet Photodissociation.

Owing to the role of the 20S proteasome in a wide spectrum of pathologies, including neurodegenerative disorders, proteasome-associated autoinflammatory syndromes (PRAAS), and cardiovascular diseases, understanding how its structure and composition contribute to dysfunction is crucial. As a 735 kDa protein assembly, the 20S proteasome facilitates normal cellular proteostasis by degrading oxidized and misfolded proteins. Declined proteasomal activity, which can be attributed to perturbations in the structural integrity of the 20S proteasome, is considered one of the main contributors to multiple proteasome-related diseases. Devising methods to characterize the structures of 20S proteasomes provides necessary insight for the development of drugs and inhibitors that restore proper proteasomal function. Here, native mass spectrometry was combined with multiple dissociation techniques, including ultraviolet photodissociation (UVPD), to identify the protein subunits comprising the 20S proteasome. UVPD, demonstrating an ability to uncover structural features of large (>300 kDa) macromolecular complexes, provided complementary information to conventional collision-based methods. Additionally, variable-temperature electrospray ionization was combined with UV photoactivation to study the influence of solution temperature on the stability of the 20S proteasome.

Tuning the properties of peptide imprinted nanoparticles for protein immunoprecipitation using magnetic streptavidin beads

Maximizing the binding properties of thermoresponsive molecularly imprinted nanoparticles (MIN) was aimed to explore their feasibility as antibody substitutes in protein immunoprecipitation (IPP) with magnetic streptavidin beads (MSB). Thermoresponsive MIN targeting the cannabinoid CB1 receptor were produced by epitope imprinting through solid-phase synthesis. It was intended to determine how different variables influenced physicochemical features, binding behaviour and immunoprecipitation of the target recombinant glutathione S-transferase tagged fusion protein (GST-CTer). Such variables included the cross-linking degree of MIN, and variables like pH, temperature or the use of Tween-20 for binding and IPP experiments. The cross-linker (CL) amount influenced the coil-to-globule transition of thermoresponsive MIN, making the lower critical solution temperature (LCST) decrease from 37.2 °C using 5% of CL, to 29.0 °C using 25%, also suggesting higher plasticity on the former. Temperature influence on size was corroborated by dynamic light scattering, observing size reductions from 250–450 nm (RT) to 70–100 nm (> LCST) for MIN produced with 5–15% of CL. However, binding behaviour did not clearly improve for more than 10% CL. Further experiments revealed that temperature and pH control were critical for efficient binding and release, selecting 40 °C and pH 5 as appropriate. Following binding experiments, the GST-CTer-MIN complex was successfully immunoprecipitated using MSB, achieving an IPP efficiency of 11.48% over the initial input protein concentration, which was calculated after SDS-PAGE separation and Western blot analysis. The methodology may be exploited for selective protein extraction and quantification from complex tissue homogenates.Graphical

Osmotic Treatment of Orange and Pink Sweet Potato-Mass Transfer Rate and Efficiency

Sweet potatoes (Ipomoea batatas) are globally cultivated due to its adaptability, high nutritional value, and short growing season, tolerance to high-temperature soils, low fertility, and minimal pest or disease issues, making it a valuable asset to the food industry. Osmotic treatment, a renowned preservation technique requiring mild temperatures and minimal energy, has gained prominence. Over ten years of research at the Faculty of Technology Novi Sad has pioneered the use of sugar beet molasses as an effective osmotic solution for drying different herbs, fruits, vegetables, and meat. This study specifically focused on osmotically treating samples of pink and orange sweet potatoes in sugar beet molasses (80% w/w) to explore the influence of solution temperatures (20°C, 35°C, and 50°C) and osmotic treatment durations (1h, 3h, and 5h) on mass transfer rate and treatment efficiency. The Principal Component Analysis (PCA) and color correlation analysis were employed to illustrate the connections between different sweet potato samples. Findings indicate that the mass transfer rate peaks at the onset of the process. Particularly with the highest temperature after 1h of osmotic treatment The highest values for RWL and RSG (13.33±0.02, 1.85±0.04 and 11.51±0.02, accordingly) were obtained for both orange ((15.19±0.08 g/(gi.s.w.·s)·105and 4.53±0.06 g/(gi.s.w.·s)·105) and pink sweet potato ((9.91±0.02 g/(gi.s.w.·s)·105 and 3.78±0.04 g/(gi.s.w.·s)·105), respectively. Notably, diffusion is most rapid within the initial three hours, suggesting potential reductions in processing time aligned with these results.

Numerical Analysis of Optimising Liquid Desiccant Dehumidification for Sustainable Building Cooling: A Data-Driven Method Using Response Surface Methodology

Leveraging data-driven methods such as Response Surface Methodology (RSM) has considerable potential for sustainable building cooling via mitigating energy consumption and environmental impacts. This research focuses on using the RSM to improve liquid desiccant dehumidification for sustainable building cooling performance using a D-optimal design. Specifically, the research intends to investigate the actual influence of the inlet air conditions and desiccant concentration on the performance of liquid desiccant dehumidification systems, i.e., the moisture removal rates and dehumidifier efficiency. To systematically conduct this research, a set of experimental data gathered from the open literature is utilised. This includes a specific set of inlet parameters of air temperature (27–34.5 °C), ratio of air humidity (20.5–25 g/kg), and solution temperature (27.5–38.5 °C) as the independent variables. Also, the feedback variables include the moisture removal rates (MRR) and efficacy (ϵ). The associated results of the analysis of variation indicate that the ratio of air humidity has the greatest influence on the moisture removal rate. However, the solution temperature and the ratio of air humidity have the most influence on efficacy. In the event of response optimisation, the result at MRR and (ϵ) are 0.54 g/s and 0.50, respectively, with a minimum desirability of 0.992 and 1.

Synthesis of poly (N-isopropylacrylamide)-poly(ε-caprolactone) for temperature-controlled wettability of poly(L-lactic acid)

Abstract In the work, poly(N-isopropylacrylamide)-poly(ε-caprolactone) (PNIPAm-PCL) with the low critical solution temperature (LCST) was synthesized by a combination of chain transfer and ring-opening method to endow poly (lactic acid) (PLLA) with the temperature-controlled wettability. The effects of PNIPAm-PCL on the thermal properties, mechanical properties, and temperature-controlled wettability were studied. At 20 wt% of PNIPAm-PCL/PLLA, the tensile strength of the material reduces slightly, but its elongation at break is enhanced significantly, which reaches 135.1%. PNIPAm-PCL/PLLA exhibits good temperature-controlled wettability. With the temperature rising from 0 to 45oC, the water contact angle increases from 29.8 ° to 80.1 °; conversely, it goes down, and there is a hysteresis. The material still has good stability and degradability. This work provides an example for the development of intelligent tissue engineering materials.

Construction and Performance Study of an Injectable Dual-Network Hydrogel Dressing with Inherent Drainage Function.

With the widespread utilization of moist wound dressings, the extended healing time and increased risk of wound infection caused by excessively moist environments have garnered significant attention. The development of hydrogel dressings that can effectively control the wound moisture level and promote healing is very important. Inspired by the pore-opening perspiration effect of the skin, this study constructed an injectable dual-network hydrogel, CMCS-OSA/AG/MXene, by the composition of a dynamic covalent network of carboxymethyl chitosan and oxidized sodium alginate based on the Schiff base and hydrogen bond network of the thermosensitive low-melting-point agar with the advantage of the upper critical solution temperature (UCST) effect. Under near-infrared (NIR) light stimulation, the CMCS-OSA/AG/MXene hydrogel shows characteristics conducive to rapid removal of wound exudate while maintaining an appropriate moist environment for the wound and excellent antibacterial effects with its photothermal responses. The excellent conductivity of the hydrogel can also promote cell proliferation under external electrical stimulation (ES). Further validation through animal experiments on a full-thickness skin defect model demonstrates the excellent capability of CMCS-OSA/AG/MXene in accelerating wound healing. This work provides an innovative approach to the development of injectable hydrogel dressing materials with inherent drainage functionality and shows a new avenue to wound moisture control and wound healing promotion.

Sol-gel synthesis, structure and adsorption properties of LiMgxMn(2-x)O4 (0 ≤ x ≤ 0.7) Oxides

Lithium manganese оxides with a spinel structure LiMgxMn(2–x)O4, doped with Mg2+ ions in the range 0 ≤ x ≤ 0.7, were obtained by sol-gel synthesis. Phase composition and morphology of obtained оxides were studied by using X-ray phase analysis and scanning electron microscopy. It is shown, that in the studied range 0 ≤ x ≤ 0.7 Mg-doped lithium manganese оxides saved the structure of the original cubic spinel LiMn2O4, while an increase in parameter a was observed from 8.175 to 8.309 Å and average crystallite size practically unchanged (30–36 nm). Samples of the initial LiMn2O4 and Mg-doped spinels were represented by prismatic particles of submicron (0.1–0.2 µm) and micron (1.0–3.0 µm) sizes, respectively. The effect of the adsorbent dose (0.05–0.3 g/l) and pH (3.0–13.0) of the solution on the adsorption efficiency was studied. The adsorption isotherms of the LiMg0.3Mn1.7O4 samples were described by the Langmuir monomolecular adsorption equation. An increase in the temperature of the model solution from 25 to 45°C was accompanied by an increase in the maximum adsorption of the LiMg0.3Mn1.7O4 samples from 10.50 to 10.98 mmol/g, which indicates the endothermic nature of the adsorption process. The kinetics of adsorption was well described by a pseudo-second order equation, which indicates the occurrence of chemical interaction during the adsorption process.

Hydrogen-induced cracking behaviors of Ni–Cr–Mo-based superalloy fabricated by wire arc additive manufacturing under different solution temperature

The hydrogen embrittlement behavior of Ni–Cr–Mo-based superalloy fabricated by wire arc additive manufacturing (WAAM) with or without solution treatment was investigated by electrochemical hydrogen charging. The results show that the dissolution of the Laves phase promotes the precipitation of the δ phase in the matrix of WAAM superalloy after solution treatment at 980 °C. When the solution temperature goes up to 1080 °C, the large Laves phase disappears and only MC exists in the matrix. The interfaces between the Laves phase/δ phase and matrix generally could act as hydrogen traps, which would reduce the motion of hydrogen and lead to high hydrogen embrittlement resistance of the WAAM and ST-980 °C samples. However, hydrogen mainly accumulates on grain boundaries in the ST-1080 °C due to the disappearance of the Laves phase and δ phase. Hydrogen-induced intergranular brittle fracture occurs during the slow strain rate tensile test and the ST-1080 °C samples exhibit higher hydrogen embrittlement susceptibility than that of the WAAM and ST-980 °C samples.

Robust, Switchable and Printable Underwater Adhesives Based on a Temperature‐Deactivated Design

AbstractConventional adhesives generally suffer from diminished adhesion in aqueous environments, posing significant challenges for their application in wet and submerged conditions. While extensive research efforts are directed toward enhancing the interfacial bonding, cohesive strength, and durability of adhesives in such environments, most existing underwater adhesives remain static and irreversible. This limitation hinders their reusability and often results in undesirable residues. Addressing the challenge of achieving strong underwater adhesion with on‐demand detachment remains crucial. This study introduces the development of temperature‐responsive underwater adhesives that demonstrate outstanding bonding strength, reversibility, and durability. Through the strategic integration of interfacial bonding, reinforced cross‐linking networks, dynamic hydrogen bonds, and upper critical solution temperature (UCST)‐driven phase transitions, one of the few temperature‐deactivated adhesives is created. The optimized adhesive is distinguished by its performance to achieve underwater adhesion strengths exceeding 1.4 MPa, nearly 100% switching efficiency and residue‐free adherend under mild thermal cycling. Beyond the template‐assisted fabrication of adhesive patches, 3D printable adhesives are achieved with programmable architectures via direct ink‐writing. This work highlights the development of temperature‐deactivated underwater adhesives activated by UCST‐type phase transitions, not only boosting adhesion strengths and switching efficiencies across various water conditions but also broadening their applicability with user‐defined and application‐specific functions.

Mussel-inspired thermo-switchable underwater adhesive based on a Janus hydrogel

On-demand underwater adhesives with excellent adhesive and gentle detachment properties enable stable connections to various biomedical devices and biointerfaces and avoid the risk of harmful tissue damage upon detachment. Herein, we present a Janus hydrogel adhesive that can reversibly switch its adhesion strength, which is controlled by temperature, using a thermoresponsive polymer and mussel-inspired molecules. This thermoswitchable adhesive (TSA) hydrogel displays both strong adhesion and gentle detachment with an over 1000-fold gap in underwater adhesion strength onto glass, titanium, aluminum, and Teflon substrates when exposed to temperatures above and below the lower critical solution temperature (LCST). The adhesion switch is possibly caused by the change in toughness of the TSA hydrogels with temperature because the Janus hydrogel possesses gradient crosslinked structures. Moreover, the lowermost surface is sufficiently soft to gently detach from the substrate below the LCST. The electrode-integrated hydrogel remains on human skin, and electrical signals are continuous over 10 min above the LCST. In contrast, commercially available hydrogel electrodes quickly swell and detach from the skin. The thermoswitchability of the TSA hydrogel, with its robust adhesion and gentle detachment, offers significant potential for biomedical applications characterized by minimally invasive procedures.

Mesoporous Fe3O4@SiO2@La nanocomposite for efficient methylene blue removal from wastewater

This study investigates the synthesis and application of Fe3O4@SiO2@La mesoporous nanocomposites for methylene blue (MB) removal from wastewater. The successful synthesis of the nanocomposite was confirmed by various characterization techniques including FE-SEM, XRD, BET/BJH, and FT-IR. The adsorption efficiency of the nanocomposite for MB removal was evaluated under different operating conditions, including initial solution pH, adsorbent dosage, contact time, and temperature. The results revealed that the nanocomposite demonstrated optimal performance at neutral pH (pH=7), with an adsorbent dosage of 0.01 g, a contact time of 5 min, and 25 °C. Kinetic studies revealed pseudo-second-order kinetics, indicating chemisorption as the rate-limiting step. Langmuir and Freundlich isotherms were applied to describe the adsorption process. The nanocomposites demonstrated excellent reusability and high removal efficiency in real wastewater samples. The enhanced MB removal efficiency of the Fe₃O₄@SiO₂@La nanocomposites is attributed to electrostatic interactions, π-π stacking, and hydrogen bonding between MB and the adsorbent surface. Overall, the synthesized nanocomposites offer a promising and efficient solution for MB removal from wastewater, demonstrating potential for practical applications in environmental remediation.

Slow release of surfactant by smart thermosensitive polymer-functionalized mesoporous silica for enhanced oil recovery: Synthesis and characterization

The efficiency of surfactant flooding can be improved through slow-release technology, which enables stimuli-sensitive and gradual release of surfactant. In this study, we synthesized a novel nanocomposite capsule composed of mesoporous silica functionalized with thermosensitive poly N-vinyl caprolactam (PNVCL). Well-optimized nanocarriers were synthesized by conducting sensitivity analyses on key synthesis parameters such as pH, reaction duration, and hydrophobic phase, resulting in hydrodynamic diameters ranging from 47 to 109 nm. Characterization of the nanocarrier structure was performed using dynamic light scattering (DLS), Brunauer–Emmett–Teller (BET) analysis, and field emission scanning electron microscopy (FESEM), while Fourier-transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), and energy-dispersive X-ray spectroscopy (EDS) were employed to analyze the nanocarrier composition. Poly N-vinyl caprolactam (NVCL)-functionalized mesoporous silica exhibited high surfactant loading (approximately 52 % w/w) and a large specific surface area (542.88 m2/g), featuring ink-bottle pores. Additionally, it demonstrated thermosensitive behavior, with the lower critical solution temperature of 39 °C. Gradual release of cetyltrimethylammonium bromide (CTAB) was observed in both deionized water and formation brine, with release rates increasing with temperature. Overall, the synthesized nanocomposite carrier holds significant potential as an ideal candidate for effectively controlling the release of surfactants in reservoirs subjected to high-temperature and high-salinity conditions.

Effect of Carbide Precipitation on Hardness and Wear Resistance of H13 Steel

The carbide precipitation of H13 steel and its effect on hardness and friction and wear resistance are investigated by microstructure observation, phase analysis, and mechanical property test. Results show that the tempering hardness is mainly related to the content of secondary carbides. After solution treatment in the temperature range of 1040–1070 °C, quenching and tempering, with the increase of the solution temperature, the content of secondary carbides and hardness of H13 steel in the tempering microstructure increase first and then decrease, and both reach the maximum value when the solution temperature is 1060 °C. The change of hardness is consistent with that of the content of secondary carbides. When the solution temperature is 1040 °C, the wear mass loss of the tempered H13 steel is the least, which is 4.63 mg, indicating that its wear resistance is the best, and this is caused by the presence of more undissolved carbides in the tempering microstructure. With the increase of the solution temperature, the wear mass loss increases gradually, and the wear resistance decreases, which is mainly related to the content decrease of undissolved and secondary carbides and the content increase of residual austenite.

Investigating the effect of temperature and concentration on the performance of reverse electrodialysis systems

Reverse electrodialysis (RED) is a membrane-based technology proposed for harvesting electricity from a salinity gradient. In this study, a detailed examination of the effect of temperature and concentration on RED membrane properties is undertaken. Modelling of the co-ion concentration as a function of temperature allows the Donnan potential to be estimated, while membrane resistance and ion diffusivity can be modelled by an Arrhenius relationship with temperature. Membrane resistance is best modelled using a reciprocal relationship with concentration, while permeability and diffusivity show a power law dependence upon concentration. Using these results, the effect of increasing the temperature of the entire RED system is compared to the case where only the temperature of the diluate solution is increased. The model is in good agreement with experimental results across temperatures from 10 to 40 °C. It shows that a comparable increase in gross power density can be achieved when only the temperature of the diluate solution is increased, relative to increasing the temperature of the entire system. However, increasing the temperature also reduces the pumping energy required for each stream. In the present case, this reduction in pumping energy with temperature is more significant than the changes within the stack itself. Thus, an increase in temperature of the entire system from 20 to 40 °C results in a 27 % increase in net power density as compared to an increase of the diluate solution alone. It is thus concluded that increasing the temperature of the entire system (rather than just the diluate stream) provides a pathway to increasing the power density of the system if waste heat is available, promoting its adoption for energy harvesting.

Enhancing the Sr uptake on resorcinol–formaldehyde polycondensates by modifying the structure and shape

AbstractResorcinol–formaldehyde polycondensates—the well-established Cs-selective agents, along with their crown ether (18-crown-6) composite discs, were synthesized, characterized (FT-IR, SEM–EDS, surface area, porosity) and applied for strontium uptake from aqueous solutions. Effects of crown ether amounts, Sr in feed, pH, equilibration time, temperature, competing ions, on the sorption, along with re-usability of synthesized sorbents, were evaluated. The fate of Sr was followed by EDXRF spectrometry on both solution and solid phases. Solution pH (3–12) and temperature (upto 100 °C) had negligible impact on the holding capacities. Sorption capacity was enhanced by ~ 33% upon modification, and followed pseudo-second order kinetics.

Study on the mechanism of improvement of mechanical properties of Al–Mg–Si aluminum alloys by Cu and Ce

First, the stability and tensile properties of the Al/Mg2Si interface doped with alloying elements in the Al–Mg–Si system of aluminum alloys are calculated from first principles. Then, the two experimental alloys with different components were heat treated and the properties were characterized. Calculations show that when the interface is doped with Cu, the tensile stress that the interface can withstand increases to 3.13 GPa; when the interface is doped with Cu and Ce, the tensile strain that the interface can withstand increases to 20% and the tensile stress that the interface can withstand increases to 4.17 GPa; when the interface is doped with Cu and Sc, the tensile strain that the interface can withstand increases to more than 25% and the tensile stress that the interface can withstand increases to 5.08 GPa or more. Characterization of the organization and properties of the experimental alloys showed that Ce not only increased the peak solid solution temperature of the alloys, but also increased the tensile and yield strengths of the alloys in the extruded state by 16% and 13.74%, respectively. During hot extrusion, Ce was able to promote the precipitation of precipitated phases. During aging, the addition of Ce promoted the aging precipitation of the alloy, which not only increased the number of precipitated phases in the alloy, but also refined the precipitated phases and enhanced the aging strengthening effect of the alloy. This study provides technical guidance for the development of new aluminum alloy materials with high strength and low cost.

Exploring LCST- and UCST-like Behavior of Branched Molecules Bearing Repeat Units of Elastin-like Peptides as Side Components.

Elastin-like peptides (ELPs) exhibit lower critical solution temperature (LCST)-type behavior, being soluble at low temperatures and insoluble at high temperatures. While the properties of linear, long-chain ELPs are well-studied, short-chain ELPs, especially those with branched architectures, have been less explored. Herein, to obtain further insights into multimeric short ELPs, we investigated the temperature-responsive properties of branched molecules composed of a repeating pentapeptide unit of short ELPs, Phe-Pro-Gly-Val-Gly, as side components and oligo(Glu) as a backbone structure. In turbidimetry experiments, the branched ELPs showed LCST-like behavior similar to conventional ELPs and upper critical solution temperature (UCST)-like behavior, which are rarely observed in ELPs. In addition, the morphological aspects and mechanisms underlying the temperature-responsiveness were investigated. We observed that spherical aggregates formed, and the branched ELPs underwent structural changes through the self-assembly process. This study demonstrates the unique temperature-responsiveness of branched short ELPs, providing new insights into the future development and use of ELPs with tailored properties.

Study on the Performance of a Novel Double-Section Full-Open Absorption Heat Pump for Flue Gas Waste Heat Recovery

Open absorption heat pumps are considered one of the most promising methods for efficiently utilizing low-grade waste heat, reducing energy consumption, and lowering greenhouse gas emissions. However, traditional heat pumps have significant limitations in the range of flue gas temperatures they can recover, and their relatively low system performance further restricts practical applications. In this study, we propose a novel double-section full-open absorption heat pump driven by flue gas from the desulfurization tower. By designing the absorber with a double-layer structure, the system can recover more latent and sensible heat from the flue gas, significantly enhancing its thermal recovery capability. Additionally, replacing the traditional LiBr/H2O working pair with LiCl/H2O significantly reduces the risks of solution crystallization and equipment corrosion. Through comprehensive research, the strengths and weaknesses of the system were explored. The results indicate that this system effectively recovers flue gas waste heat within the temperature range of 30–70 °C. Specifically, at a flue gas temperature of 70 °C and a flow rate of 3 kg/s, the system achieves a COP of 1.838, along with a heating capacity of 158.83 kW and a ROI of 34.1%. These metrics demonstrate that the system not only delivers high performance but also exhibits excellent economic viability. Additionally, when the solution temperature is lowered to 10 °C, the system’s maximum COP reaches 1.96, reflecting a significant 30.67% improvement over traditional heat pumps. These findings highlight the system’s potential for application in coal-fired power plants, where varying levels of power output can benefit from enhanced thermal recovery and efficiency.

Bidirectional Temperature‐Responsive Thermochromic Hydrogels With Adjustable Light Transmission Interval for Smart Windows

AbstractThermochromic smart windows have been widely developed for solar regulation to save building energy. However, most current smart windows still exhibit a single responsiveness to a specific temperature, which is not conducive to daytime energy saving or nighttime privacy protection. Herein, a low‐temperature response is achieved by pre‐initiation of the monomer acrylamide (AAm) and acrylic acid (AA) in the synthesis of P(AAm‐co‐AA). Then, N‐isopropyl acrylamide and AAm are introduced into P(AAm‐co‐AA) to form a pre‐polymerized precursor solution. The liquid precursor solution can be encapsulated within two quartz glasses and synthesized in situ to prepare smart windows, which exhibit a high visible light transmittance of 84.4%, excellent solar modulation of 69.5%, and bidirectional temperature responsiveness (cold and hot). In addition, the upper critical solution temperature and the lower critical solution temperature of the hydrogel and the light transmission interval between the two temperatures can be flexibly adjusted to adapt to different climates and individual user needs. The designed smart window maintains a high light transmission within the human body's comfort temperature range. The bidirectional temperature response window achieves the dual functions of energy saving and privacy protection, making it an ideal smart window candidate with good prospects for practical applications.