Networked control systems with network-induced delay, packet loss and parameters uncertainty is modeled in this paper, consider the sensors that can’t send information to controller and the actuators that can’t receive information calculated and sent by the controller, the integrity design of the networked control system with sensors failures and actuators failures is analyzed based on robust fault-tolerant control theory. Parametric expression of controller is given based on feasible solution of linear matrix inequality. After detailed theoretical analysis, the simulation results is provided, which further demonstrated the proposed scheme.