Asphalt solidification of hospital waste Incineraten fly ash was studied based on that asphalt can immobilize the heavy metals in fly ash. In the nature hospital waste incineraten fly ash, the leachate concentration of Zn (279.2 mg/L) and Pb (19.88 mg/L)) were significantly higher than the regulatory limit by TCLP test while the leachate concentration of Cu (1.51 mg/L), Cd(0.97 mg/L) and Ni (0.49 mg/L) were respectively beyond the regulatory limit of TCLP. In the asphalt solidified hospital waste incineraten fly ash, the leachate concentration of the heavy metals increased with the increase of fly ash rate in solidified fly ash from 10% to 40%, and the leachate concentration of 5 studied heavy metals were under the limit of the standard.