Solid-tubular Carcinoma Research Articles

A CASE OF LOCALLY ADVANCED BREAST CARCINOMA 25 YEARS AFTER AN AUGMENTATION MAMMAPLASTY

A case of locally advanced breast carcinoma after augmentation mammaplasty is reported, and carcinogenesis in response to foreign bodies and the differential diagnosis between foreign body granuloma and breast cancer are discussed. The patient was a 51-year-old woman into whose breasts silicone-fluid had been injected 25 years ago. A mass with an ulcer was found in her right breast, and a subcutaneous mastectomy was performed based on a diagnosis of foreign body granuloma. The tumor was intraoperatively diagnosed by the frozen section technique to be a ductal carcinoma. A radical mastectomy was immediately performed. Microscopically, the tumor was found to be solid-tubular carcinoma with positive nodes, and foreign bodies and granulomas were found to be present in or adjacent to the tumor tissue.

SURGICAL TREATMENT OF SYNCHRONOUS TRIPLE CANCERS INCLUDING BREAST, GASTRIC AND COLON CANCER

A 44-year-old female was admitted to our hospital with a painless tumor in the right breast. A standard radical mastectomy was performed due to the detection of cancer. A histologic examination revealed a solid-tubular carcinoma [Stage I (t1n1αm0)]. Following the operation, she was given a prescription for 5-FU (200mg), PSK (3g) and TAM (20mg) to be taken each day. On the 101st day after discharge, she was admitted to our hospital again complaining of epigastralgia. On the gastroendoscopy and the barium enema, a gastric cancer and a colon polyp were detected. A distal partial gastrectomy (R2) and abdominal polypectomy were performed. A histologic examinaiton revealed a signet-ring cell carcinoma [Stage I (H0P0n0m)] in the gastric cancer and a carcinoma of the adenoma in the colon polyp. She recovered well after the operation. Our experience of this case has emphasized the significance that adequately planned examination schedule is vital for detecting the secondary cancers in early stages.