Solid Food Research Articles

Large-Caliber Empiric Esophageal Dilation Results in Sustained Improvement for Selected Patients With Nonobstructive Dysphagia.

Empiric esophageal dilation (EED) remains a controversial practice for managing nonobstructive dysphagia (NOD) secondary to concerns about safety and efficacy. We examine symptom response, presence of tissue disruption, and adverse events (AEs) after EED. We examined large-caliber bougie EED for NOD at 2 tertiary referral centers: retrospectively evaluating for AEs. Esophageal manometry diagnoses were also reviewed. We then prospectively assessed EED's efficacy using the NIH Patient-Reported Outcomes Measurement Information System disrupted swallowing questionnaire to assess dysphagia at baseline, 1, 3, and 6 months after EED. Treatment success was defined by improvement in patient-reported outcome scores. AE rate for large-caliber dilation in the retrospective cohort of 180 patients undergoing EED for NOD was low (0.5% perforations, managed conservatively). Visible tissue disruption occurred in 18% of patients, with 47% occurring in the proximal esophagus. Obstructive motility disorders were found more frequently in patients with tissue disruption compared with those without (44% vs 14%, P = 0.05). The primary outcome, the mean disrupted swallowing T -score was 60.1 ± 9.1 at baseline, 56.1 ± 9.5 at 1 month ( P = 0.03), 57 ± 9.6 at 3 months ( P = 0.10), and 56 ± 10 at 6 months ( P = 0.02) (higher scores note more symptoms). EED resulted in a significant and durable improvement in dysphagia and specifically solid food dysphagia among patients with tissue disruption. EED is safe in solid food NOD and particularly effective when tissue disruption occurs. EED tissue disruption in NOD does not preclude esophageal dysmotility.

Sources of free sugar in the diet of Saudi children.

Data concerning sources of free sugar (FS) in the diet of Saudi children are limited. Identification of the top sources of FS would permit to develop tailored interventions that aid in meeting the recommendations of the World Health Organization for FS (≤ 25 g/day). This study aimed to investigate sources of FS in children's diet. A cross-sectional data of healthy children ages between 6 and 12 years who reside in Saudi Arabia were gathered from their mothers using online platforms (WhatsApp, Facebook, and X) (n = 424; 210 boys and 214 girls). An interview was conducted through the phone with the mother and her child to collect data pertaining FS intake using a validated food frequency questionnaire. The primary sources of FS were Sweetened Beverages, followed by Sugars, Sweet Bakery Products, Other Desserts, and Candies, of which the added sugar consisted mostly of its total sugar. The consumption of FS coming from solid food sources for the highest quartile of children almost doubled the amount of FS coming from liquid food sources. Compared to boys, girls in the top quartile of FS intake consumed significantly higher amounts of solid sugars (p = 0.030). Only the intake of FS coming from Sweetened Beverages was associated negatively with age of children (p = 0.032). Public health interventions should emphasize the necessity of reducing the consumption of the top sources of FS to practically achieve the recommendations of FS intake.

Micronutrient intake from complementary foods of Asian New Zealand infants

The complementary feeding period (6-23 months of age) is when solid foods are introduced alongside breastmilk or infant formula and is the most significant dietary change a person will experience. The introduction of complementary foods is important to meet changing nutritional requirements(1). Despite the rising Asian population in New Zealand, and the importance of nutrition during the complementary feeding period, there is currently no research on Asian New Zealand (NZ) infants’ micronutrient intakes from complementary foods. Complementary foods are a more easily modifiable component of the diet than breastmilk or other infant milk intake. This study aimed to compare the dietary intake of micronutrients from complementary foods of Asian infants and non-Asian infants in NZ. This study reported a secondary analysis of the First Foods New Zealand cross-sectional study of infants (aged 7.0-9.9 months) in Dunedin and Auckland. 24-hour recall data were analysed using FoodFiles 10 software with the NZ food composition database FOODfiles 2018, and additional data for commercial complementary foods(2). The multiple source method was used to estimate usual dietary intake. Ethnicity was collected from the main questionnaire of the study, answered by the respondents (the infant’s parent/caregiver). Within the Asian NZ group, three Asian subgroups were identified – South East Asian, East Asian, and South Asian. The non-Asian group included all remaining participants of non-Asian ethnicities. Most nutrient reference values (NRV’s)(3) available for the 7-12 month age group are for total intake from complementary foods and infant milks, so the adequacy for the micronutrient intakes from complementary foods alone could not be determined. Vitamin A was the only micronutrient investigated in this analysis that had an NRV available from complementary foods only, allowing conclusions around adequacy to be made. The Asian NZ group (n = 99) had lower mean group intakes than the non-Asian group (n = 526) for vitamin A (274µg vs. 329µg), and vitamin B12 (0.49µg vs. 0.65µg), and similar intakes for vitamin C (27.8mg vs. 28.5mg), and zinc (1.7mg vs. 1.9mg). Mean group iron intakes were the same for both groups (3.0mg). The AI for vitamin A from complementary foods (244µg) was exceeded by the mean intakes for both groups, suggesting that Vitamin A intakes were adequate. The complementary feeding period is a critical time for obtaining nutrients essential for development and growth. The results from this study indicate that Asian NZ infants have lower intakes of two of the micronutrients of interest than the non-Asian infants in NZ. However, future research is needed with the inclusion of infant milk intake in these groups to understand the total intake of the micronutrients. Vitamin A intakes do appear to be adequate in NZ infants.

Esophageal stenosis as a result of a right aortic arch in 2 cats

A 3-month-old and a 4-year-old cat were presented in the clinic due to regurgitation. The kitten had displayed the symptoms since it had been fed solid foods and was smaller than the litter mates. The 4-year-old cat showed sudden-onset symptoms for 5 days prior to presentation and had a good general condition. Positive contrast thoracic radiographs of both cats in lateral recumbency showed an esophageal dilatation cranial to the heart base and raised a suspicion of foreign material with soft tissue density in this area. In the 4-year-old cat, findings of ventrodorsal thoracic radiographs were compatible with a dextroposition of the aorta and a slightly marked focal left curve of the trachea. The echocardiographic examination of the kitten pictured a right sided aorta, hence a vascular ring anomaly with a dextroposition from the aorta was suspected. Aberrant blood flow as it is seen in a persistent ductus arteriosus was not apparent in the echocardiography. As a result of the sudden development of the clinical signs in the older cat without displaying any former history of regurgitation, an esophagoscopy was performed to exclude an intraluminal esophageal cause for the stricture as well as to extract the foreign material. In this cat, computed tomography imaging also displayed an aberrant left subclavian artery. Both cats recovered well after surgical correction.The diagnosis of a ring anomaly in the kitten via echocardiography is a rare situation. As is the diagnosis of a high-grade esophageal stricture due to a vascular ring anomaly at the age of 4 without a former history of regurgitation.Recovery was excellent in the younger cat. There were no signs of regurgitation 6 months after surgery. The adult cat was in good general condition without clinical symptoms according to the owners when presented for stitch removal. Unfortunately, the adult cat was lost to follow up.

The correlation between parental education and childbirth sequence with the provision of early complementary feeding to children aged 1-5 years in the working area of the Lawahing Community Health Center, Alor Regency, East Nusa Tenggara, Indonesia

Introduction: According to the World Health Organization(World Health Organization), exclusive breastfeeding is when the baby only receives breast milk from the mother without providing liquids or other solid food, except for syrup containing vitamins, mineral supplements, or medicines that a doctor has approved. Indonesia's exclusive breastfeeding coverage in 2021 is 61.33% (1), East Nusa Tenggara Province's success rate for exclusive breastfeeding is 57.8% (2), Lawahing Community Health Center's exclusive breastfeeding coverage is 30%, and the other 70% have been given complementary feeding from under four months of age. Objective: This study aims to analyze the correlation between parental education and childbirth sequence with the provision of early complementary feeding to children aged 1-5 years in the working area of ​​the Lawahing Community Health Center, Alor Regency, East Nusa Tenggara Methods: This research was an observational analytical study with a cross-sectional approach. The sample from this study was 214 children aged 1-5 years who met the inclusion and exclusion criteria. The independent variables in this study are parental education and childbirth sequence, and the dependent variable is early complementary feeding for children aged 1-5 years. The data analysis used was the chi-square test. Results: Based on the results of the chi-square statistical test, it was found that there was a significant correlation between parental education(p-value < 0.01) and childbirth sequence(p-value < 0.01) by providing early complementary feeding to children aged 1-5 years in the working area of ​​the Lawahing Community Health Center, Alor Regency, East Nusa Tenggara. Conclusion: There was a significant correlation between parental education and childbirth sequence with the provision of early complementary feeding to children aged 1-5 years in the Lawahing Community Health Center, Alor Regency, East Nusa Tenggara working area.

Physiochemical and Sensory Properties of Edible Cups Conceptualized from Food By-Products

ABSTRACT: Our community today is going through multiple challenges, in the arena of nutrition and the environment. The use of plastic or paper containers to pack foods is on a huge rise proportional to the increase in the purchase of outside foods. In terms of environment, the concern is with the the improper disposal of plastics, which destroys volumes of species, causes pollution in land and water, elevates greenhouse gas emissions and contaminates the food chain, in health perspective, there is arise in the pervasiveness of various non-communicable diseases because of several carcinogenic,toxic, and hazardous chemicals present in foods we consume packed in those containers. As an alternative initiative, this study aims to formulate nutritive edible cups utilizing wheat flour as the major ingredient, and the by-products of the food industry namely rice bran, dehulled chickpea flour, groundnut cake, pomace of beetroot, apple, and molasses in different proportions, thereby providing a solution to disposal of waste products from food industry also. The edible cups formulated with different proposition of the listed ingredients were subjected to Organoleptic and functionality evaluation. The accepted variation of the edible cup was further analysed for nutritional composition and phytochemical composition. The results show that these nutritive edible cups were found to be palatable and can be utilized to serve solid and semi-solid foods and can be consumed along with the served food. The edible cups provide sufficient energy(354Kcals), carbohydrates(74.2g), fat(1.5g), protein(10.8g), fiber(4.6g), polyphenols, flavonoids, and phytochemicals.

Acute and two-week effects of neotame, stevia rebaudioside M and sucrose-sweetened biscuits on postprandial appetite and endocrine response in adults with overweight/obesity—a randomised crossover trial from the SWEET consortium

BackgroundSweeteners and sweetness enhancers (S&SE) are used to replace energy yielding sugars and maintain sweet taste in a wide range of products, but controversy exists about their effects on appetite and endocrine responses in reduced or no added sugar solid foods. The aim of the current study was to evaluate the acute (1 day) and repeated (two-week daily) ingestive effects of 2 S&SE vs sucrose formulations of biscuit with fruit filling on appetite and endocrine responses in adults with overweight and obesity. MethodsIn a randomised crossover trial, 53 healthy adults (33 female, 20 male) with overweight/obesity in England and France consumed biscuits with fruit filling containing 1) sucrose, or reformulated with either 2) Stevia Rebaudioside M (StRebM) or 3) Neotame daily during three, two-week intervention periods with a two-week washout. The primary outcome was composite appetite score defined as [desire to eat + hunger + (100 − fullness) + prospective consumption]/4. Findings Each formulation elicited a similar reduction in appetite sensations (3-hour postprandial net iAUC). Postprandial insulin (2-hour iAUC) was lower after Neotame (95% CI (0.093, 0.166); p < 0.001; d = -0.71) and StRebM (95% CI (0.133, 0.205); p < 0.001; d = -1.01) compared to sucrose, and glucose was lower after StRebM (95% CI (0.023, 0.171); p < 0.05; d = -0.39) but not after Neotame (95% CI (-0.007, 0.145); p = 0.074; d = -0.25) compared to sucrose. There were no differences between S&SE or sucrose formulations on ghrelin, glucagon-like peptide 1 or pancreatic polypeptide iAUCs. No clinically meaningful differences between acute versus two-weeks of daily consumption were found. InterpretationIn conclusion, biscuits reformulated to replace sugar using StRebM or Neotame showed no differences in appetite or endocrine responses, acutely or after a two-week exposure, but can reduce postprandial insulin and glucose response in adults with overweight or obesity. FundingThe present study was funded by the Horizon 2020 program: Sweeteners and sweetness enhancers: Impact on health, obesity, safety and sustainability (acronym: SWEET, grant no: 774293).

Exploring breastfeeding patterns and barriers in a Kerala tertiary care hospital: a cross-sectional study

Background: Exclusive breastfeeding is vital for maternal and child health, yet challenges persist. This study in a Kerala tertiary care hospital aimed to assess prevalence, identify barriers, and explore cultural influences. Aim was to determine the prevalence of exclusive breastfeeding, uncover the barriers mothers face, and explore cultural factors affecting infant feeding choices. Methods: Utilizing Google forms, 274 postpartum women were surveyed. Participants provided data on awareness, practices, challenges, and factors influencing their infant feeding choices. Results: While 94.9% were aware of the ideal breastfeeding duration, only 74.1% practised exclusive breastfeeding until six months. Inadequate breast milk, sore nipples, and family pressure emerged as challenges. The timing of solid food introduction significantly impacted exclusive breastfeeding. Conclusions: Our study offers insights into exclusive breastfeeding practices. Culturally sensitive interventions, comprehensive support systems, and healthcare provider engagement are crucial. This study echoes recent research, emphasizing the multifaceted nature of exclusive breastfeeding practices, calling for diverse and context-specific strategies to empower mothers and ensure infants receive the best nutritional start.

Degree of swallowing impairment in the elderly: clinical and instrumental assessment

ObjectiveTo classifying the degree of swallowing impairment in the elderly, comparing clinical and instrumental assessment. MethodsThis is a cross-sectional study with quantitative and qualitative analysis of clinical and instrumental assessment of 37 elderly, aged 60–82 years, of both genders without neurological, oncological or systemic diseases, participated in this study. All participants were submitted to clinical evaluation and their results compared through fiberoptic endoscopic evaluation of swallowing considering liquid, pudding and solid food consistencies. Data were analyzed descriptively and statistically using the analysis of variance test (two-way ANOVA) and Tukey's post hoc test (p < 0.05). ResultsIn the clinical evaluation there was a higher occurrence of moderate swallowing impairment, followed by functional swallowing, while in fiberoptic endoscopic evaluation of swallowing the severity of the impairment was greater for moderate and mild degrees. There was no statistical difference between the clinical and instrumental evaluation methods. However, there was a significant interaction between the variables, with a difference for liquid consistency in the instrumental evaluation method. ConclusionHealthy elderly have different degree of swallowing impairment according to food consistency. The clinical assessment using a scale that considers the physiological changes of the elderly, presented results similar to those found in the instrumental examination. Level of Evidence2.

Identifying elevated child weight from 3 to 24 months: Early transitions into nonparental care and to solid foods.

Early entry into nonparental care (NPC) and introduction to solid foods (ITS) have been linked to elevated weight, however, little research exists on the combined influence of these transitions on child weight over time. Identify groups of children based on early NPC and ITS timing and examine whether NPC-ITS groups differentially affect child weight over time. Data were drawn from STRONG Kids2 (n = 468). Primary predictors include NPC (by 3M)-ITS (< or ≥6M) groups; outcome variables include child weight-for-length/height z-scores (WFL/WFHz) (3, 12, 18, and 24 months). Multilevel regression was used to examine the NPC-ITS groups as predictors of child WFL/WFHz. Six groups were identified: 27% Parental Care-ITS before 6M, 31% Parental Care-ITS after 6M, 12% Daycare-ITS before 6M, 14% Daycare-ITS after 6M, 10% Kincare-ITS before 6M, and 7% Kincare-ITS after 6M. Children who were in daycare (regardless of ITS) or kincare-ITS before 6M demonstrated the highest WFL/WFHz over time, compared to their parental care counterparts. NPC-ITS combinations on child WFL/WFHz across the first 2 years of life highlight the need for a partnership approach among parental and nonparental caregivers to support the feeding of infants throughout the transition to solid foods.

Age‐related changes in sweetness perception: Exploring the role of cross‐modal interactions

AbstractCrossmodal strategies have been proven to be useful to enhance sweetness perception, although, in general, the segmentation of consumers is not an essential part of this kind of research. The aim of the present study was to determine if a set of crossmodal strategies could be useful to modify sweetness perception in three different age groups: young, middle‐aged, and senior adults. A butter cookie and a milkshake sample were reformulated (appearance and aroma of both samples, and the mouthfeel of the milkshake) to assess liking and perception of overall flavor and sweetness intensities. Results suggested that adding a sweet‐related aroma enhanced sweet taste/flavor intensity, without affecting liking ratings, for all the studied age groups. Liking and the ratings for flavor and sweetness intensity were significantly different among age groups, but no interactions “sample x age” were identified, suggesting that crossmodal interactions were similar for all age groups.Practical ApplicationsThe growing demand for low‐sugar foods has led food companies to reformulate their products, requiring research into the best ways to develop successful low‐sugar alternatives. Research on potential crossmodal interactions is useful to guide companies to attend consumers' demands, but there is a lack of information on how to adapt the most successful strategies to each consumer segment (beyond cross‐cultural studies). Results of the present research include interesting data on three different consumers' segments and their perception of two kinds of products in which cross‐modal strategies were used to reformulate a control sample: a solid food ‐exemplified using a butter cookie‐ and a beverage ‐exemplified using a milkshake‐.

Semi-dynamic in vitro digestion of sourdough bread enriched with flaxseed oil coacervates

Food structure and addition of encapsulated compounds can impact the gastro-intestinal digestion of food. Flaxseed oil was encapsulated by complex coacervation using soluble pea protein and gum arabic as shell materials, dried by either spray or electrostatic spray drying and incorporated into sourdough dough before baking. Three bread formulations were prepared using spray-dried (B-SD), electrospray-dried coacervates (B-ES) and free ingredients used in the encapsulation (B). The standardised semi-dynamic INFOGEST in vitro digestion method was used. Cumulated protein/free NH2 release and cumulated free fatty acids (FFA) release were used to assess protein and lipid digestion. Coacervates were resistant to bread preparation since they were visible in B-SD and B-ES. The total release of protein, free NH2 and FFA by the end of intestinal digestions ranged between 41.58–45.23%, 1.08–1.22 µmol/g protein and 22.26–63.54%, respectively. There were no significant differences between formulations. There was a statistically significant increase (p < 0.5) of about three times in FFA release between the oral and gastric phases. Our findings help to understand the behaviour of coacervates when incorporated into solid food. In this study, the delivery structures did not affect in vitro digestion and may be used to increase the polyunsaturated fatty acid content by 50%.

Essential and Toxic Elements in Infant Cereal in Brazil: Exposure Risk Assessment.

Infant cereals, one of the first solid foods introduced to infants, have been reported to pose risks to human health because they contain toxic elements and an excess of essential elements. The objective of this study was to assess the cancer and non-cancer risk of exposure to essential and toxic elements in infant cereal in Brazil. In our analyses, we included data from 18 samples of infant cereals made from different raw materials and estimated the incremental lifetime cancer risks and non-cancer hazard quotients (HQs) for their consumption. Rice cereal is particularly concerning because it is immensely popular and usually contains high levels of inorganic arsenic. In addition to arsenic, we assessed aluminum, boron, barium, cadmium, chromium, copper, lead, manganese, nickel, selenium, silver, strontium, and zinc. The cancer risk was highest for rice cereal, which was also found to have an HQ > 1 for most of the tested elements. Inorganic As was the element associated with the highest cancer risk in infant cereal. All of the infant cereals included in this research contained at least one element with an HQ > 1. The essential and non-essential elements that presented HQ > 1 more frequently were zinc and cadmium, respectively. The cancer and non-cancer risks could potentially be decreased by reducing the amount of toxic and essential elements (when in excess), and public policies could have a positive influence on risk management in this complex scenario.

The effect of early childhood caries on chewing function and tolerated food texture levels in preschool children.

The early form of caries can affect solid food consumption. The aim of the study was to evaluate the effect of oral health status on chewing performance, and tolerated food texture among preschool children suffering from early childhood caries (ECC). A cross-sectional study was conducted with a sample of 109 children aged between 3 and 6 years, who were allocated to three groups (severe-ECC (s-ECC), ECC and control) on the basis of their caries. Chewing function was evaluated by using the 'Karaduman Chewing Performance Scale (KCPS)' and the Turkish version of the 'Mastication Observation and Evaluation instrument (T-MOE)', and the tolerated food texture was determined by the 'International Dysphagia Diet Standardization Initiative (IDDSI)'. Carious lesions, oral hygiene and gingival health status were evaluated by using the 'decayed, missing, filled tooth/surface indices (dmft/s)', 'plaque and gingival indices'; respectively. A total of 56 children (51.4%) had s-ECC, 39 (35.8%) had ECC and 14 (12.8%) had no caries (control group). KCPS showed that 26 (86.7%) children suffering from s-ECC were at level 1, and 11 (100%) children were at level 2. Seven (100%) children with s-ECC had IDDSI level-5. All children with healthy oral status had IDSSI level-7. Compared to the ECC and control groups, the s-ECC group had significantly lower scores from the T-MOE total and subscale scores (p < .001). The evaluation of chewing performance during routine dental examinations of children with ECC (especially s-ECC) may considerably contribute to the early diagnosis of chewing problems and the provision of necessary oral rehabilitation.

Effect of complementary feeding using the baby-led weaning method on development in toddlers: a narrative review

Background: The baby-led weaning (BLW) approach can introduce complementary food to six-month-old infants. This method offers large pieces of solid foods such as vegetables, meat, and fruit. BLW can encourage children's development, especially motor skills such as chewing and speaking. This literature review aimed to determine the definition and technique of the BLW in giving complementary feeding and identify the effect of using the BLW method on toddler development. Methods: The type of research was a literature review based on the review process of research articles that discuss the effect of BLW on toddler development. The search for articles was done from the Google Scholar and PubMed databases. Results: The author found infants were introduced to complementary feeding late from standard weaning. Initially, the baby is offered finger food and allowed to eat alone. BLW significantly affects children's development, especially in helping to form independence, preventing picky eater behaviour, stimulating children's fine motor skills, and improving oral motor skills. Conclusion: The mother offered late complementary feeding with different types of food and techniques from the standard method. The BLW could significantly influence toddler development.

The effects of Calorie restriction and Bariatric surgery on Circulating Proneurotensin levels.

Proneurotensin (pNT) is associated with obesity and T2D, but the effects of Roux-en-Y gastric bypass (RYGB) on postprandial pNT levels are not well studied. Assess effects of RYGB versus very low-energy diet (VLED) on pNT levels in response to mixed-meal tests (MMT), and long-term effects of RYGB on fasting pNT.Study participants: Cohort 1: Nine normoglycemic (NG) and ten T2D patients underwent MMT before and after VLED, immediately post-RYGB and six weeks post-RYGB. Cohort 2: Ten controls with normal weight and ten patients with obesity and T2D, who underwent RYGB or vertical sleeve gastrectomy (VSG), were subjected to MMTs and GIP infusions pre-surgery and three months post-surgery. GLP-1 infusions were performed in normal weight participants. Cohort 3: Fasting pNT was assessed pre-RYGB (n=161), two months post-RYGB (n=92) and 1-year post-RYGB (n=118) in NG and T2D patients. pNT levels were measured using ELISA. Reduced fasting and postprandial pNT were evident after VLED and immediately following RYGB. Reintroduction of solid food post-RYGB increased fasting and postprandial pNT. Prior to RYGB, all patients lacked a meal response in pNT, but this was evident post-RYGB/VSG. GIP- or GLP-1 infusion had no effect on pNT levels. Fasting pNT were higher 1-year post-RYGB regardless of glycemic status. RYGB causes a transient reduction in pNT as a consequence of caloric restriction. The RYGB/VSG-induced rise in postprandial pNT is independent of GIP and GLP-1 and higher fasting pNT are maintained one year post-surgically.

Ultrasonic monitoring of softening in solid foods during in-vitro gastric digestion

This study aims to evaluate the feasibility of using non-destructive ultrasound to monitor textural softening in potato and cheese during in vitro gastric digestion. Textural measurements were taken after different digestion times (5, 10, 15, 20, 25, 30, 60, 90, and 120 min) at 37 °C, while in vitro digestion was non-destructively monitored using ultrasound in through-transmission mode.The textural softening resulted in a substantially greater variation in hardness, ranging from 0.418 to 1.241 N for potato and from 0.200 to 0.534 N for cheese. Meanwhile, the ultrasonic velocity increased during gastric digestion from 745 ± 106.6 m/s to 1342.9 ± 131.5 m/s in potato and from 1377.4 ± 3.8 m/s to 1502.8 ± 4.6 m/s in cheese. Both the softening and velocity increase were attributable to the compositional variation occurring within the food structure due to gastric fluid diffusion into the food matrix. The Weibull model kinetic parameter “k” indicated that potato exhibited a higher softening rate than cheese, due to a faster gastric fluid migration. This was also evidenced by the effective diffusivity of gastric fluid (Deff) obtained by modeling the evolution of the ultrasonic velocity during digestion (Deff, potatõ2.5 Deff, cheese). A noticeable relationship was found between the softening of both food matrices and the change in the ultrasonic wave velocity. Additionally, it should be highlighted that the measurement of the ultrasonic velocity by ultrasound presented a lower degree of variability than instrumental texture assessment. Therefore, ultrasound proves to be an accurate technique for the on-line monitoring of textural changes in foods during in vitro digestion. This non-destructive approach provides a powerful instrumental tool in the design of new products with enhanced nutritional properties by better monitoring how in vitro digestion affects their mechanical properties.

Damage to the esophagus in combination with hereditary motor and sensory neuropathy: description of a clinical case in a 12-year-old child

The article discusses a clinical case of a combination of achalasia of the cardia complicated by candidal esophagitis, which led to severe dysphagia and a significant decrease in body weight of a patient suffering from hereditary motor and sensory neuropathy - Charcot-Marie-Tooth disease (CMT) type 4 E. The authors highlight the pathogenesis and clinical picture diseases, features of the course of achalasia in a patient with a hereditary neurological disease. In this clinical case, an example of a disease in a 12-year-old girl is considered. A feature of this patient was progressive dysphagia, which ultimately led to the almost complete impossibility of normal food intake and the development of nutritional insufficiency. CMT disease is a heterogeneous group of hereditary disorders affecting the peripheral nervous system, as a result of the progression of the disease, motor and sensory dysfunction develops, such patients are under the supervision of neurologists. The presence of atypical symptoms, including not only progressive muscle weakness and exhaustion, with sensory deficits in the distal parts of the limbs, but also the severity of dysphagia, which from episodic becomes permanent, prevents the passage of not only solid food, but also liquid through the esophagus, the occurrence of esophageal vomiting - should serve as the basis for a complete examination of the patient using methods that allow visualization of the esophagus. In the available domestic literature, no description of the combined course of the pathological conditions indicated in the observation was found; isolated cases are given in the foreign literature, so the description of this clinical observation is relevant for raising awareness and early diagnosis of gastrointestinal smooth muscle dysfunction against the background of polyneuropathy.

A co-designed evaluation study to identify Breastfeeding Knowledge of General Practitioners' and Practice Nurses'.

The World Health Organization and American Academy of Paediatrics recommend exclusive breastfeeding until 6 months of age, with continued breastfeeding along with complementary solid foods for up to 2 years and beyond. Despite the well-established importance of breastfeeding, Irish rates remain the lowest in Europe. Healthcare professionals' breastfeeding knowledge and skills have a positive impact on increasing breastfeeding rates. There is limited evidence of the knowledge, attitudes or practices of general practitioners (GPs) and general practice nurses (GPNs), which is essential to breastfeeding in Ireland. The aim of this study was to evaluate the breastfeeding knowledge, attitudes and practices of GPs and GPNs in one community healthcare organisation (CHO) in Ireland. A co-designed evaluation study was used following low-risk ethical exemption (LS-LR-22-161). A modified version of a validated breastfeeding questionnaire was developed. A Project Steering Committee was established that included patient, and public involvement stakeholders. The anonymised survey was distributed via online Qualtrics platform (November 2022-February 2023). STROBE Guidelines were utilised. The overall response rate was 25.9% (n = 121) and valid responses were reported in the article. The total population size was n = 468 (GPs n = 290 and GPNs n = 178). Our pilot study identified that 42.7% (n = 47/110) of respondents never attended a breastfeeding education programme, and 53.9% (n = 55/102) identified that their knowledge could be improved. The majority of respondents, 92.9% (n = 92/99) wish to complete further education in breastfeeding. The results of this pilot study in one CHO in Ireland indicate a gap in knowledge and a need for specific breastfeeding and lactation theoretical and skills training for GPs and GPNs working in primary care to support, promote and protect breastfeeding.

Potential of gaseous ozone to inhibit Aspergillus flavus and detoxify aflatoxin B1 in agar and broth media (solid and liquid food states) at different growth phases

Agricultural food crops are prone to Aspergillus flavus contamination during post-harvest and storage stages. Their consumption is toxic due to aflatoxin production, a potent carcinogenic and immunosuppressive agent. Present study explored the ozone's effect as a function of food media states (solid and liquid) to inhibit Aspergillus flavus under three modes of treatment (0th-day, Every-day and Nth-day ozone treatment), that adds novelty to the work. Results showed that ozone concentration to treat Aspergillus flavus and aflatoxins is higher in liquid than solid food state. Further, ozone treatment affected the intactness of fungal spores and inhibited 100% conidial growth. It also exhibited 88 %% inhibition and 90% reduced biomass in solid and liquid food states. Effectiveness of ozone towards inhibiting Aspergillus flavus and aflatoxin was in the following order: Nth -day treatment > Every-day treatment > 0th -day ozone treatment. Further, growth studies showed ozone treated cultures exhibit delayed sporulation and aflatoxin production by 72 h. when cultured on fresh media. Additionally, ozone purging into extracted aflatoxin led to > 99% degradation. The above results show the significance of ozone technology in increasing the shelf-life of post-harvested food crops. Further, it can be used as a disinfectant in the food industry to treat contaminated food crops/liquid products by detoxifying aflatoxins.