An experiment was conducted to evaluate the effects of combination of Catfish (Pangasius hypophthalmus) by-product protein hydrolysate (BTP) and Beta-glucan in diets on the performance of weaned piglets. The study was conducted according to a randomized complete design with 3 treatments and 4 replications (pen) as the experimental unit (3 piglets/pen). A total of 36 castrated male weaned piglets (Landrace x Yorkshire) at 26-28 days of age were allocated in the experiment. The control diet contained marine fish meal (BC) as the sole protein supplement diet (ĐC) and the others were two experimental diets in which crude protein (CP) from BC in ĐC was replaced by the CP from BTP and with (BTPB) or without (BTP) Beta-glucan supplementation. Results showed that, the highest and the lowest average daily gain (ADG) over the 5 week period after weaning were recorded for piglets on BTPB (393.3 g/day) and ĐC (315.7 g/day) diets. Average daily feed intake (ADFI) were of non significant differences (p >0.05) in all treatments. Therefore, feed conversion ratio (FCR) was lowest in BTPB (1.76 kg feed/kg gain) and highest in ĐC (2.18 kg feed/kg gain) (p
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