Solar-driven seawater desalination provides a promising technology for sustainable water energy harvesting. Although tremendous efforts have been dedicated to developing efficient evaporators, the challenge of preventing salt accumulation while simultaneously realizing high-performance steam-electricity cogeneration remains to be addressed. In this work, inspired by the water and solute transportation in plants via the wicking mechanism, a one-way asymmetric nanofluidic photothermal evaporator fabricated by disproportionately depositing photothermal MXene nanosheets on a hydrophilic cotton textile is reported for simultaneous freshwater and power production. By unidirectionally driving dynamic saline transportation via this photothermal cotton textile pump, this evaporator not only enables self-operating salt rejection for stable steam generation but also affords continuous electric power generation induced by the formation of an asymmetric double electrode layer within MXene nanochannels under the drenching state. Specifically, the solar-driven evaporation rate and voltage generation reach 1.38 kg/m2/h (with a conversion efficiency of 83.1%) and 363 mV under 1 sun irradiation, respectively. Notably, this designed nanofluidic system suffers negligible performance depreciation after 30 h of operation and washing 15 times, which indicates its outstanding stability and reusability. This facile design of the asymmetric nanofluidic photothermal system may provide prospective opportunities for scaling up sustainable freshwater and electric power production.