As the demand for kidney transplantation, particularly from living donors, continues to interest in outlining the demographic profile of rise, there is an increasing and much needed these renal donors.1,2Developing countries as India have witnessed an increase in the number of voluntary donors, especially females.3 This gender disparity is seen more in developing countries and requires targeted counseling and research to understand whether the cause is medical or sociocultural obstacles.4 The aim of this study was to analyze all living donor kidney transplants performed at our institution, which caters to people of varied communities and socioeconomic backgrounds. This was a retrospective cohort study of all 600 kidney donors who underwent donor nephrectomy at a single transplant center (Mahatma Gandhi Hospital, Jaipur) between 2013 and November 2018. Patient demogra- phics including gender, age, and relationships between donors and recipients were obtained Demographics and gender relationships: There were 600 donor kidney transplants conducted at Mahatma Gandhi Hospital, Jaipur, between 2013 and November 2018. Tables 1 and 2 highlight the baseline demographics of donors and recipients, with significant differences observed in some comparative markers. We observed a significant increase in the number of voluntary renal donations almost doubling every year from 24 donations in 2013 to 48 in 2014, 98 donations in 2015, 128 donations in the year 2016, and 161 donations until November 2018. Out of the 600 renal donations till November 2018, 97.4% (585) were living donors and 2.6% of donations were deceased donors. Among the pre donation characteristics, the mean age of the donors was 44.0 ± 11 years at the time of renal donation. The mean body mass index observed in our study was 21.4 ± 0.06. Family history of hypertension was present in 14% (n = 600) and family history of diabetes in 10% (n = 600), and none of the donors had renal disease in the family. Majority (78%) of the donors were females, whereas males contributed to 21.8% of renal donations. Relation of donors to recipients: We observed that mothers contributed to be the highest number of donors accounting for 181 donations (n = 600), followed by wives who contributed to 102 of renal donors (n = 600), and 98 (16.3%) fathers donated to their children. Fifteen percent of the donors donated kidney to their siblings (Table 3). We found that there were more donations from women to male patients than from male donors to female patients (P <0.001), whereas donations from male donors to male patients were similar. Women were more likely to be the living donor in partner-to-partner kidney transplants (17%) than men (1.66%). 600 donor kidney transplants is one of only a few studies to explore the relationship between gender disparities. Our study confirmed some well-known observations consistent with living donor kidney transplant (e.g. more female donors and less female recipients).We found gender disparity in living donor kidney transplant in a single center that caters to a population of varied cultures and socio economic backgrounds. We anticipate that these results will guide clinicians and living donor coordinators and lead to appropriate counseling for patients and potential donors.