Businesses may adopt strategies and practices that support sustainable development goals. Such strategies include considering social and environmental impacts as well as prioritizing socio-environmental benefits at a higher level than profits. Supportive practices comprise enhancing social benefits and limiting environmental harm. What SDG-related strategies and practices are businesses pursuing? Are businesses implementing practices and strategies? Do the practices and strategies differ across societies? A survey of representative samples of 399 businesses in Colombia and 413 businesses in Egypt was conducted in 2021, by the Global Entrepreneurship Monitor. The owner-managers reported that they frequently had strategies that considered social and environmental impacts of business operations, and they prioritized socio-environmental considerations over financial goals. In Columbia, there were more frequent practices that enhanced social benefits and limited environmental harm than in Egypt. In addition, strategies were implemented in practices supporting the SDGs more in Colombia than in Egypt. Our findings contribute to understanding business strategies that consider SDGs and their implementation in practices that are embedded in society.