Perspective Of Society Research Articles

Route Optimization of Hazardous Material (Hazmat) Transportation with Risk Equity and Time-Varying Risk

This paper strives for route optimization of hazardous material (hazmat) for given probabilities and consequences. We aim to not only develop a model to determine the route with the least total risk and cost, but also pursue risk equity from three perspectives of government, enterprises, and society in the route optimization. Specifically, this paper reduces the differences of population exposure risk among road segments by using the threshold setting method and decreases the differences of environmental risk by minimizing the risk compensation cost caused by the additional environmental risk exceeding its average for each road segment. In addition, this paper analyzes the impact of the time-varying characteristics of risk and risk equity and proposes a multi-objective route optimization model which considers the minimization of total risk, cost, and risk differences under time-varying conditions. Finally, the ε-constraint method and an improved genetic algorithm are used to optimize the model, which is applied to a case study involving hazardous materials transportation route optimization in Shanghai, China. The resulting analyses indicate that risk equity can be improved by setting a proper threshold to acquire feasible paths and by minimizing the compensation cost to control the differences of environmental risk. Considering variance of time in the route optimization may lead to a route with lower risk and better risk equity.

Proanthocyanidins supplemented diet alter anti-aging-markers and improved lifespan in Drosophila melanogaster model

BackgroundIt is unequivocally believed that phenolics and flavonoids from fruits and vegetables hold robust prevention potentials against age-related disease development through their abundant hydroxyl groups. This study explored the potential neuromuscular enhancement and anti-aging effects of dietary supplemented proanthocyanidins-rich fraction from Tamarindus indica on Drosophila melanogaster model. One- to three-day-old male and female D. melanogaster were fed with a proanthocyanidins-rich fraction-supplemented diet for 7 days at two different concentrations. Following the effective dose determination, longevity assay (rate of survival), behavioral assay (negative geotaxis and eclosion), and biochemical assays (aging and antioxidant enzymes activities) were conducted to assess the fraction’s longevity, antioxidant, and anti-aging effects on D. melanogaster model.ResultThe results showed a significant (p < 0.05) improvement in the rate of emergence and lifespan of the flies fed with proanthocyanidins-rich fraction-supplemented diet at both concentrations (1.5 mg/g and 2.5 mg/g) compared to the normal control. A significant decrease in acetylcholinesterase (AChE) activity and the level of caspase-3 and caspase-9 were observed in the D. melanogaster flies fed with the fraction-containing diet when compared with the normal control. The supplemented diet also significantly increases the activity of catalase, superoxide dismutase (SOD), and glutathione-s-transferase (GST) in a concentration-dependent manner but not nicotinamide quinone oxidoreductase one (NQO1) in D. melanogaster upon comparison with the normal control.ConclusionThe observable changes in the experiment were attributed to the T. indica-derived proanthocyanidins, flavonoids with robust biological activities. The flavonoid-rich fraction proved its potential by enhancing the antioxidant system in D. melanogaster via the increase in the activities of some of the phase II antioxidant enzymes. The present study provides more insights into the wider perspectives of societies on the use of plant-derived natural compounds as the potential approach toward prevention against aging and age-related morbidities which enhance wellness and the quality of life in humans and animals.

Analysis of Self-Regulation in the Rencong Telang Islamic Society Perspective of Social Cognitive Theory

Analysis of Self-Regulation in the Rencong Telang Islamic Society Perspective of Social Cognitive Theory

Cost Effectiveness of Additional Preoperative Telephone Call to Increase Surgical Preparedness: Analysis of a Randomized Clinical Trial.

There is a need for cost effective interventions that increase surgical preparedness in urogynecology. We performed an ancillary prospective economic evaluation of the Telehealth Intervention to Increase Patient Preparedness for Surgery (TIPPS) Trial, a randomized multicenter trial that evaluated the impact of a preoperative telehealth call on surgical preparedness in women undergoing urogynecologic surgery. A within-trial analysis from the health care sector and societal perspective was performed. Cost-effectiveness was computed from health care sector and societal perspectives, with an 8-week time horizon. A total of 126 women were included in our analysis. QALYs gained were similar between groups (telehealth 0.1414 + 0.0249; usual care 0.1409 + 0.0179). The cumulative mean per-person costs at 8 weeks from the healthcare sector perspective were telehealth call: $8696 +/- 3341; usual care: $8473 +/- 3118 (p = 0.693) and from the societal perspective were telehealth call: $11,195 + 5191; usual care: $11,213 +/- 4869 (p = 0.944). The preoperative telehealth call intervention was not cost effective from the health care sector perspective with an ICER of $460,091/QALY (95%CI -$7,382,608/QALY, $7,673,961) using the generally accepted maximum willingness to pay threshold of $150,000/QALY (Neumann et al. N Engl J Med. 371(9):796-7, 2014). From the societal perspective, because incremental costs per QALY gained were negative $-35,925/QALY (95%CI, -$382,978/QALY, $317,226), results suggest that preoperative telehealth call dominated usual care. A preoperative telehealth call is cost effective from the society perspective. Registered with http://ClinicalTrials.gov . Date of registration: March 26, 2019 Date of initial participant enrollment: June 5, 2019 URL: https://clinicaltrials.gov/ct2/show/record/NCT03890471 Clinical trial identification number: NCT03890471.

Social Media Managers’ and Journalists’ Role in Maintaining Local Wisdom in A Mediatized Rural Area

&lt;p class="Default"&gt;&lt;strong&gt;Introduction:&lt;/strong&gt; This study explores on how social media managers and journalists in Tulungagung narrating ‘Aksi 212’ (Action 212) protests. Social media managers and journalists are the actors who have an active role in producing, constructing and sharing information. The solidarity protests and the news about ‘Aksi 212’ had appeared in various media and regions in conflicting narratives. However, there was no news nor any solidarity protest occurred in Tulungagung.&lt;/p&gt;&lt;p class="Default"&gt;&lt;strong&gt;Methods:&lt;/strong&gt; This study applies digital ethnography to examine five media that keep updating their posts and interview six journalists and media managers who have a large number of followers in Tulungagung.&lt;/p&gt;&lt;p class="Default"&gt;&lt;strong&gt;Findings: &lt;/strong&gt;The social media managers and journalists avoid any information that may bring a potential conflict, eventhough it becomes a national issue. On the date of the ‘Aksi 212’, the @radar_tulungagung and @hits_tulungagung accounts did not share any posts. Meanwhile, the @jtv_tulungagung, @kacamata_tulungagung and @tulungagung_sparkling uploaded local news. The social media managers and journalists provide information in accordance with the local wisdom--the harmony and togetherness--as they realize the legal and social consequences.&lt;/p&gt;&lt;strong&gt;Originality:&lt;/strong&gt; The previous mediatization studies focus on the role of the media as institutions and examine the ‘Aksi 212’ in the context of political conflict. This study examines the ‘Aksi 212’ by using the socio-constructivist approach to understand the mediatization from the perspective of the rural society, that upholds the local wisdom in their media engagement and observes the society’s practice in utilizing media.

Sustainability of pneumococcal conjugate vaccination in Ghana: a cost-effectiveness analysis in the context of donor transition.

Streptococcus pneumonia is responsible for 18% of infant deaths in Ghana. With co-financing from Gavi in 2012, Ghana introduced the PCV13 into the childhood immunization programme to reduce the burden of Streptococcus pneumonia. However, Ghana will graduate to the Gavi fully self-financing phase in 2026, when the nation assumes full responsibility of paying for the PCV13. This research aims to evaluate the health impact and cost-effectiveness of PCV13 immunization in Ghana since its implementation and after the cessation of support from Gavi. We used the UNIVAC tool to evaluate two main scenarios of cost-effectiveness, from vaccine introduction (2012-2025) and after Gavi transition (2026-2031) in comparison with no vaccination. The sources of data include national data, international estimates and expert opinion. Cost was considered from both the government and societal perspectives. We discounted health outcomes at 3%. Currency values were stated in US Dollars. We tested the robustness of the base case results by performing scenario and sensitivity analyses. PCV13 will reduce the pneumococcal disease burden by 48% from 2012 to 2031. The vaccination programme costs are USD 130 million and USD 275 million in 2012-2025 and 2026-2031 respectively. It also has a budget impact of USD 280 million for the 2026-2031 period from the perspective of government. The incremental cost-effectiveness ratios are USD 89 and USD 73 respectively from the perspectives of government and society in 2012-2025. The incremental cost-effectiveness ratios are USD 530 and USD 510 respectively from the perspectives of government and society in 2026-2031. The PCV13 vaccination programme in Ghana is cost-effective at 50% GDP per capita threshold even when Gavi withdraws co-financing support from 2026 onwards.

Navigating success: Human resource management and customer service in Chinese K12 shadow education companies

K12 private tutoring (shadow education) supplementing mainstream education is popular in China. K12 shadow education companies aiming to succeed in both private business and public school competitions need to figure out what factors affect their success. Most studies about Chinese K12 shadow education focused on the development and status from the perspective of education and society. This paper uses quantitative and qualitative methods to collect and analyze data from questionnaires and in-depth interviews. The data from in-depth interviews support and supplement the data from questionnaires. From the management viewpoint, this paper provides a new model for K12 shadow education companies. It comes up with the idea that human resource management and customer service are the critical factors for 12 shadow education companies to succeed. This study provides meaningful references for the more rational development of K12 education companies in an ever-changing social environment.

Data driven value creation in industrial services including remanufacturing

In the era of twin transition companies face complex challenges. Economical resource usage and efficiency are particularly important in the manufacturing sector. Product-service systems are seen a promising solution that can meet the expectations regarding efficiency in a sustainable way. However, there is a huge potential regarding the evaluation of sustainable value creation. The paper focuses on the value creation process in product-service systems including offers with remanufactured products.Against this background, the goal of this paper is to describe how data driven industrial services can create sustainable value in the meaning of the triple bottom line. Based on previous work, a quantitative model for the assessment and optimization of this value creation is extended to include additional remanufacturing strategies. The value optimization model integrates the different perspectives of provider, custumer and society. The numerical evaluation of this model for a specific application case shows that economic and ecological value creation can be jointly achieved and optimized, and which service arrangements lead to this optimization.

Aborted Women's Feelings and Experiences with Abortion: A Qualitative Study

Objective: This study aimed to reveal the feelings and experiences of women who had abortions based on their own experiences. Method: The qualitatively designed study was conducted with 11 women who applied to a Training and Research Hospital in Istanbul for abortion and met the inclusion criteria. The data were collected by the researchers with an 11-question participant information form and a semistructured interview form consisting of five questions. Results: The themes obtained from the research were determined as "The meaning of abortion", "The meaning attributed to the abortion decision", "Family and social support", "Community attitude" and "Attitude of healthcare professionals". Conclusion: Women who have had abortions are influenced by the perspective of society, religious values, and the approach of health professionals. There is a need to develop procedures that will positively affect women's abortion experiences.

Gender Role and Hate Speech Representation in Web Series

Abstract: In India, media has been an essential component of life. The effect of the media can be seen with this that majority of people across the globe rely on various media platforms to increase consciousness and get information for enjoyment and to gain knowledge about a variety of other global events. Denis McQuail (2000) believes that “the media is accountable for illuminating and fostering systematic exposure, as well as influencing ideas and ideals.” Furthermore, according to the BARC (Broadcast Audience Research Council) Report, 2019, “web series are defined as popular shows with high viewing that cover a wide range of socio-cultural elements of people's life.” There are several types of streaming platforms for entertainment that broadcast 24*7. India much like other jurisdictions has been struggling with the issue of how to control hate speech on the internet. Regulating internet hate speech is a complex issue. The aim of this study is to examine web series in the perspective of Indian society. The stereotypical images of women and hate speech, including abusive language and rude behavior, and discrimination on the basis of religion and caste, have been portrayed in Indian web series. The current study intends to investigate how the Indian web series content structure continues to impact gender role and hate speech representation on streaming platforms.

Book Review of A Brief History of Oil: From Technological Progress to Changing the World

In order to explore the connection between oil and economy, society and politics, and grasp the future development trend of the oil field, Vaclav Smil introduced the development history of oil from the perspective of economy, society and politics, and then discussed the problems encountered by human beings in oil exploration, production, transportation, refining and sales, and introduced the huge creativity gradually accumulated by human beings in the process of extracting and processing oil, which made crude oil the world's most important source of energy. A Brief History of Oil: From Technological Progress to Changing the World is a book by Vaclav Smil, which consists of 12 chapters in 5 parts. It mainly covers the advantages and disadvantages of oil; The composition of oil and the geological conditions of its extraction; The improvement of oil exploitation technology and the discovery of super-large oil fields; Discovery of recoverable crude oil, development of oil fields, the management of extraction, refining and transportation; Finally, it concludes with reflections on the future of oil under the new pattern of energy strategy. The feature of this work is to obtain analytical data by examining the relationship between petroleum and society, economy and politics, to provide support for the optimization of petroleum system, and to provide scientific reference for scientists, educators, and managers engaged in the petroleum industry.

Analysis of the Use of Technology from the Perspective of Islamic Family Law in Era 4.0

Industrial revolution 4.0. causing a shift in lifestyle from a social, religious pattern to a materialistic and secular individual pattern. Apart from that, the cultural sector has been disrupted due to the development of social media which has reconstructed the cultural structure of society. Social relations between communities are now more closely established in the virtual world, so that relationships in the real world have become relative. This results in a lack of direct communication with family members because they focus on seeking their own pleasure. In the era of the industrial revolution 4.0, parents have also given gadgets to their children aged around 4-6 years. This research uses a social approach method and structural functionalism as its theory. The results of the research are that families do not reject revolution and use technology to help their daily lives. Apart from that, there are implications of structural functionalism theory with the occurrence of disruption in the era of the industrial revolution, especially in the social and cultural fields of society. The Industrial Revolution Era 4.0 is an era where various things in life are filled with sophisticated technology. Several families that the author studied have used technology produced by the industrial revolution 4.0. They use it in their daily lives so that it is felt as a need and urgency. As a result, there is a shift in perspective and lifestyle in society in various areas of life, one of which is social and cultural, resulting in disruption. The disruption process has gone through a process of externalization, objectification and internalization as per the theory of structural functionalism so that both are relevant.

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Implementation of Masbuk Hadith in Congregational Prayer: Perspectives of Today's Society

The debate among ulama over the applicability of the masbuk hadith in congregational prayer for individuals who are alone at the back of the saf and the significance of observing its application in Makassar City's Islamic community are the driving forces behind this research. This research design is qualitative in nature that combines literature study with field study. Literature study uses Syuhudi model analysis. Field study uses Miles model analysis. The results showed that scholars differed in assessing the quality of the Hadith about the rule of masbuk in congregational prayer because of the controversial narrators. Those who consider the narrator flawed, the Hadith is daif and cannot be practiced. Those who praise the narrator, the hadith is accepted and practiced. The implementation of the hadith in the religious practices of the Muslim community in Makassar City is still low, only 15.15%. The implementation of the masbuk rule in congregational prayers, the people of Makassar City practice two ways, namely choosing to stand alone at the back of the row or pulling someone in the front to go back to accompany him in the back row. The first way, reached 51.52%, the second way only 48.48%. الملخص خلفية هذا البحث هي إختلافات العلماء حول وقوف الرجل منفردا خلف الصف عند المسبوق في صلاة الجماعة، وكذلك أهمية النظر في تطبيق حديثه في المجتمع الإسلامي بمدينة مكسار. تعتمد الدراسة منهجية نوعية ويجمع بين الدراسة المكتبية والدراسة الميدانية. تستخدم الدراسة المكتبية تحليل نموذج شهودي. وأما الدراسة الميدانية تستخدم تحليل نموذج مايلز. وتظهر نتائج البحث اختلاف آراء العلماء في تقييم جودة الحديث في أحكام المسبوق في صلاة الجماعة بسبب إختلافهم علي الراوي هل كان عادلا أومجروحا. واستنتج الذين انتقدوا الراوي مجروحا أن الحديث ضعيف، فلا يمكن العمل به. ومن يعتبر الراوي عادلاً فيكون الحديث مقبولا معمولا. لا يزال تطبيق الحديث في الممارسات الدينية للمجتمعات الإسلامية في مدينة مكسار منخفضًا، حيث يبلغ 15.15% فقط. وأغلبهم يطبقون التعاليم الإسلامية المبنية على شروح الفقه الإسلامي دون فهم حديثه. تطبيق أحكام المسبوق في صلاة الجماعة التي يمارسها المجتمع الإسلامي في مدينة مكاسار. أولاً، اختر الوقوف بمفرده خلف الصف. ثانيا أو اجترر رجلا من الصف لمرافقته فيصلي معه. النموذج الأول أكثر عددا (51.52%) من النموذج الثاني فقط (48.48%) الكلمات المفتاحية: الحديث؛ مسبوق؛ صلاة الجماعة؛ السند Abstrak Penelitian ini dilatarbelakangi oleh kontroversi ulama terkait aturan masbuk dalam salat berjamaah bagi yang sendirian di belakang saf, serta pentingnya melihat implementasi hadis masbuk di masyarakat Islam di Kota Makassar. Desain penelitian ini bersifat kualitatif yang menggabungkan studi pustaka dengan studi lapangan. Studi pustaka menggunakan analisis model Syuhudi. Studi lapangan menggunakan analisis model Miles. Hasil penelitian menunjukkan bahwa ulama berbeda pendapat dalam menilai kualitas hadis tentang aturan masbuk dalam salat berjamaah, karena adanya perawi yang kontroversial. Mereka yang mencela perawi tersebut menyimpulkan bahwa hadisnya daif sehingga tidak bisa diamalkan. Mereka yang menilai perawinya terpuji, maka hadisnya dapat diterima dan diamalkan. Implementasi hadis dalam praktik keagamaan masyarakat Islam di Kota Makassar masih rendah, hanya 15.15%. Mayoritas mereka melaksanakan ajaran Islam berdasarkan penjelasan fikih ulama tanpa memahami hadisnya. Pelaksanaan aturan masbuk dalam salat berjamaah, masyarakat Kota Makassar mempraktikkan dua cara, yaitu memilih berdiri sendiri di belakang saf atau menepuk bahu seorang makmum di depan untuk mundur mendampinginya di belakang saf. Cara pertama lebih banyak, mencapai 51.52%, cara kedua hanya 48.48%. Kata Kunci: Hadis; Masbuk; Salat Berjamaah; Sanad

Strategic Communication Management: Crafting a Positive Image for Madrasah Excellence

This research aims to determine the management of communication strategies in building the image of madrasas and changing the public's perspective towards MTs Miftahul Ulum Krejengan Probolinggo. The analysis uses a qualitative approach of case study type. This research focuses on communication strategies in building a madrasah sutra at MTs Miftahul Ulum Krejengan Probolinggo. The selection of a qualitative approach aims to understand communication strategies in building the image of madrasas at MTs Miftahul Ulum Krejengan Probolinggo. The case study was chosen to focus on the case under study. The research results show that MTs Miftahul Ulum carries out two communication management, namely internal communication management and external communication management. MTs Miftahul's internal communication management has an essential impact on creating a solid organization, using personal and group communication. Communication management is also carried out to solve organizational conflicts or problems. External communication management is carried out by MTs Miftahul to maintain organizational relationships with external parties and build the image of MTs Miftahul. Relations with the government, banking, press, consumers, surrounding community, and other organizations. This research provides implications regarding the importance of educational institutions in maintaining the image of madrasas by implementing communication strategies that impact image-building and changing society's perspective.

Distance from a cultural model of substance use risk, internalization, and self-stigma in urban Brazil.

A cognitive theory of culture as socially distributed cultural models has proven useful in research. Cultural models exist in two forms: the model shared by individuals in a social group, and individual versions of that model modified by personal experience. In previous research we documented a shared cultural model of substance use risk among a general population sample in urban Brazil. Here we examine how this model is distributed among persons under treatment for substance use/misuse and the implications for perceived and self-stigma. A convenience sample of 133 persons under treatment rated the influence of risk factors for substance use/misuse. The configuration of those ratings and the cultural distance of persons under treatment from the general population model were calculated. Degree of stigma perceived in the wider society and degree of self-stigma were also assessed. Persons under treatment aggregate risk factors to a greater extent than the general population. Using a cultural distance metric, the more distant persons under treatment are from the general population model, the lower their self-stigma regarding substance use. Some individuals under treatment separate their understanding of substance use/misuse from shared perspectives in the wider society, which in turn reduces self-stigma. These findings add an additional perspective on the relationship of culture and the individual.

Civil Society Perspectives on Rights and Freedoms in the Association of Southeast Asian Nations

Abstract This pan-regional analysis of non-governmental organisations’ (NGO) perspectives on the contemporary factors which constrain or repress civil society in the Association of Southeast Asian Nations (ASEAN) is based on United Nations’ Universal Periodic Review (UPR) data. It shows that, paradoxically, whilst the majority of ASEAN states have ratified the International Covenant on Civil and Political Rights (ICCPR) that upholds civil society’s political role in promoting rights and democracy, this is inimical to the region’s political elites who regard civil society’s primary function as non-political delivery of social welfare and development. This disjuncture results in repression, performativity, and legitimation. The UPR data reveal an ever-shrinking civil space. Civil society, including human rights defenders (HRD s), faces a raft of rights pathologies, including threats, violence and murder—as well as increasing state restrictions on freedom of association and expression. This is compounded by impunity for offenders, corruption, and government inaction following earlier UPR recommendations.

Unlocking Second Language Mastery Navigating the Complex Terrain of Adult Language Acquisition

This paper mainly focuses on the more effective way that language learners who “escaped” during the critical period of acquiring a second language. In the paper, we use the methodology of bibliography to compare the essential differences between children and adult learners from the perspectives of linguistics, neurolinguistics, society and culturology, and further study SLA theory based on the author’s own educational experience. It is an indisputable fact that older language learners have less flexibility and plasticity than children due to their mature brains. However, it can be partially compensated for by cognitive ability and social experience thus overtaking a corner. Nonetheless, some points are especially worth paying attention to, such as the necessity to “design” the grammar into the structure of the paragraph to be the “guiding framework” of thinking; Learners should not be excessively concerned about the accuracy of grammar and words at academic level, so as to avoid negative emotions such as anxiety, which affect language learning, and is partly consistent with the SLA’s Affective Filter Hypothesis. This research offers fresh guidelines for students and teachers of second languages to consider contemporary methods of teaching and learning, particularly the “fanatics” of “natural acquired” or “academically structured education.” Additionally, researchers and teachers who consider upgrading teaching methods offer evidence and inspiration owing to the growing popularity of artificial intelligence.

Urban resilience assessment and its spatial correlation from the multidimensional perspective: A case study of four provinces in North-South Seismic Belt, China

Modern cities are facing increasingly complex challenges, and assessing urban resilience is crucial to improve their ability to withstand various types of shocks and disasters, especially in the China's North-South Seismic Belt with frequent tectonic activities and natural disasters. To address this issue, this study determined the weights of the assessment system based on the entropy weight method, and evaluated the urban resilience of four provinces in China's North-South Seismic Belt in multiple dimensions from the perspectives of society, economy, infrastructure, and ecology. Furthermore, we systematically explored the spatiotemporal trends of urban resilience and its spatial correlation from 2011 to 2021. Lastly, the assessment results were validated and analyzed by four historical earthquake cases using national polar-orbiting partnership - visible infrared imaging radiometer suite (NPP-VIIRS) nighttime light data. The findings reveal that the average urban resilience index increased from 0.027 to 0.058 from 2011 to 2021, signifying a remarkable surge of 115.42%. Sichuan emerged as a consistent frontrunner in terms of urban resilience. Overall, the study area shows a spatial distribution pattern of higher urban resilience in the east and lower resilience in the west, due to the larger population and more developed economy in the east. However, the south has a higher average annual growth rate, while the north has a lower average annual growth rate. A notable observation is the gradual reduction in the coefficient of variation of urban resilience from 0.823 in 2011 to 0.751 in 2021, indicating a decline in the disparity of resilience levels. Meanwhile, Moran's I gradually increased from 0.2017 in 2011 to 0.4476 in 2021, signifying a progressive intensification in the spatial correlation of urban resilience and an evident propensity toward aggregation. By selecting shifts in the total nighttime light index (TNLI) during representative earthquake incidents as an indirect gauge of urban resilience levels, this study finds congruence with the assessment outcomes, thereby further substantiating the precision of the urban resilience evaluations. Policymakers should prioritize the allocation of resources to less resilient cities to improve their ability to withstand and recover from disaster events. The urban resilience assessment system in this study, despite its multidimensionality, may still not be able to fully cover all the factors affecting urban resilience. This study provides a significant decision-making basis for policymakers in urban development and disaster response, as well as a useful reference for building a more robust and sustainable urban future.

A cost-effectiveness analysis of pre-pregnancy genetic screening for deafness: an empirical study in China.

This research aims to assess the effectiveness and cost-effectiveness of pre-pregnancy deafness screening policies. Married couples from Shanghai, Beijing, and Suzhou in China were enrolled. We conducted high-throughput, pre-pregnancy genetic screenings for deafness in women and their partners. We compared the cost-effectiveness of deafness genetic screening with the status quo. The two-step screening (wife then partner) and following treatments and interventions were included in the decision tree model. We conducted a cost-effectiveness analysis based on the decrease in deaf newborns, healthy newborn births, and cost-utility analysis of pre-pregnancy deafness genetic screening separately. Cost, utility, and probability data used in the three models were collected from a survey combined with literature and expert consultants. A 5% discount rate and a series of one-way sensitivity analyses along with a Monte Carlo simulation were used to test the reliability of this research. Between Jan 1, 2019, and Dec 31, 2021, we recruited 6,200 females and 540 male spouses from community health service centers in Shanghai, Beijing, and Suzhou. The incremental cost-effectiveness ratio (ICER) for reducing deaf newborn births was USD 32,656 per case and USD 1,203,926 per case for increasing one healthy newborn birth. This gap exists because of the overall decrease of newborn births. From the perspective of the whole society, deafness genetic screening is not cost-effective for reducing the overall quality-adjusted life years (QALY) in the population. Pre-pregnancy genetic testing is effective in decreasing the occurrence of congenital deafness. It is a cost-saving measure when compared with the costs of future medical expenditure and income loss for the affected families. However, such screening and preventive avoidance of pregnancy will decrease the population size and QALY. Only post-screening ART with PGT was shown to increase the birth of healthy newborns. Focusing on key groups such as premature births or consanguineous couples may improve the societal effects of screening.