Depression is a formidable global health concern, with numerous individuals traditionally seeking relief through face-to-face Cognitive Behavioral Therapy (CBT). While this modality has proven effective, several barriers – including accessibility constraints, prevalent societal stigmas, and high treatment costs – have highlighted the need for more adaptable treatment avenues. This paper delves into the potential of online CBT as a transformative digital solution, with its assessment grounded in a comprehensive review of articles published between 2016 and 2021 that specifically examine the modality's efficacy in addressing depression. Preliminary findings indicate that online CBT not only produces clinically significant improvements across a spectrum of depression severities but also holds promise for widespread global implementation. The modality's intrinsic attributes, such as scalability, adaptability, and expansive reach, certainly bolster its appeal. However, as venturing further into this digital therapeutic frontier, an unwavering commitment to maintaining intervention quality and proactively navigating the inherent challenges becomes paramount to ensuring that online CBT consistently delivers its promise in the battle against depression.