Cognitive-behavioral psychotherapeutic interventions have been empirically validated as effective treatments for patients suffering from anxiety disorders.l Treatment protocols are available describing the details of the cognitive-behavioral treatment strategies applied to each anxiety disorder.2 However, as practicing clinicians have long realized, and what clinical researchers are more recently paying attention to, more often than not, patients with a principal diagnosis of an anxiety disorder suffer from additional comorbid psychiatric disorders as well, especially mood, personality, and other anxiety disorders.3-5 High rates of comorbidity are not limited to patients with anxiety disorders, and are frequently encountered among patients with a principal diagnosis of commonly occurring mood disorders as well.6 Based upon the studies mentioned above, approximately two-thirds of patients are diagnosed with at least one additional disorder. In light of these data, it appears as though protocols describing the treatment of a single disorder are typically not sufficient to address the patient's entire psychopathology. While to date, there are very few studies examining the impact of comorbidity on treatment outcome (traditionally, most studies have focused only on the principal disorder), the available data suggest that anxiety-disorder patients with comorbid Axis I and Axis II psychiatric disorders display more severe symptoms,78 are less responsive to treatment,9-l3 and are more likely to require additional treatment.I4 These findings are certainly corroborated by clinicians. Nevertheless, much of the conceptualization of treatment strategies for patients with anxiety disorders, including both psychological and pharmacological interventions, follows a single-disorder-based model. To a large degree, this way of thinking is influenced by our current classification system. Although the DSM-IViS allows for the assignment of multiple diagnoses, the use of this categorical diagnostic system often provides the clinician with a false sense of patient homogeneity (i.e., all patients with a particular diagnosis are the same). In addition, by focusing on the diagnosis of syndromes, the presence of comorbid symptoms that may not be severe enough to warrant a diagnosis for a syndrome may be missed or downplayed. While, as mentioned above, patients typically suffer from at least two disorders, it is even more common for patients to present with symptom comorbidity. In these instances, patients with a principal diagnosis of a specific disorder may manifest symptoms of one or more other disorders, yet not fulfill diagnostic criteria to warrant a comorbid diagnosis. Features, such as panic attacks, social evaluative fears, worry, phobias, obsessivecompulsive thoughts/behavior, and depression, which are the identifying characteristics of panic disorder, social phobia, generalized anxiety disorder, specific phobia, obsessive-compulsive disorder, and major depression/ dysthymia, respectively, are often present to some degree in patients suffering from any one specific anxiety disorder.16 For example, independent of whether diagnostic criteria for a mood disorder are satisfied, the majority of panic-disorder patients report a moderate level of depressive symptomatology.8 The presence of depression, even though not severe enough to warrant the diagnosis of a depressive disorder, is likely to have an impact upon treatment. Considering the emerging data on the extent and significance of syndrome and symptom comorbidity, to offer comprehensive treatment, one must implement an intervention that addresses the patient's full range of symptoms. Thus, it appears as though a more parsimonious approach to the assessment and psychotherapeutic treatment of anxiety-disorder patients is one which is symptom focused, rather than disorder based. Unlike the disorder-based approaches, symptom-focused treatment provides a framework that allows the clinician to tailor his/her treatment to address the specific symptom configuration of each patient, maximizing treatment efficiency. …