The workplace has been established as one of the priority settings for health promotion and disease prevention in the 21st century. The workplace directly influences the physical, mental, economic and social wellbeing of workers and in turn the health of their families, communities and the society. This paper therefore is of the opinion that the workplace is an ideal priority setting for health promotion because of the approaches, benefits, and the fact that a healthy qualified and motivated workforce future success in a globalizing market place can be achieved with a healthy, qualified and motivated workplace. This paper explains the concepts of the workplace, health promotion and disease prevention approaches and benefits. Conclusion and recommendation were made to enhance the use of health promotion in the workplace because better health produces better people and better performance.