Purpose Despite the various benefits of social networking services (SNSs), users have begun to experience fatigue in recent years, as evidenced by a decline in active user numbers. This relatively new phenomenon has only recently received significant managerial and academic attention. The antecedents of SNS fatigue are still unclear in the literature. The purpose of this paper is to identify the key factors causing SNS fatigue, based on a socio-technical approach. Design/methodology/approach The authors empirically tested this research model with 424 SNS users via an online survey. Structural equation modeling with partial least squares was used to analyze the data. Findings The results showed that the social factors of social comparison, social interaction overload, social surveillance and social information overload, and the technical factor of system complexity are significantly related to SNS fatigue. Practical implications This research benefits SNS providers by allowing them to better understand how to effectively design social networking platforms to retain and attract more users. It also benefits users by providing guidance on how to actively manage their own behavior to avoid potential negative outcomes induced by SNS usage. Originality/value This study focuses on the “dark side” of SNS from the perspective of fatigue, extending existing research on technostress. It also extends the applicability of the socio-technical approach to the phenomenon of SNS fatigue. Moreover, it enriches SNS fatigue research by addressing the importance of both social and technical factors in causing SNS fatigue.