Treleaven J, LowChoy N, Darnell R, Panizza B, Brown-Rothwell D, Jull G. Comparison of sensorimotor disturbance between subjects with persistent whiplash-associated disorder and subjects with vestibular pathology associated with acoustic neuroma. Objective To determine if differences exist in reported symptoms and in outcomes of sensorimotor tests (cervical joint position error [JPE], neck-influenced eye movement control, postural stability) between subjects with persistent whiplash and subjects with unilateral vestibular pathology associated with acoustic neuroma. Design Repeated measures, case controlled. Setting Tertiary institution and metropolitan hospital. Participants Twenty subjects with persistent whiplash, 20 subjects with acoustic neuroma, and 20 control subjects. Interventions Not applicable. Main Outcome Measures Symptom descriptors, Dizziness Handicap Inventory (short form), measures of cervical JPE, the smooth pursuit neck torsion (SPNT) test, and forceplate measures of postural stability in comfortable and narrow stances. Results The results showed differences in SPNT ( P=.00), selected measures of postural stability ( P<.04), and reported symptoms between the whiplash and vestibular groups. There was no between-group difference in cervical JPE ( P>.27) or dizziness handicap ( P>.69). Conclusions This study showed differences in sensorimotor disturbances between subjects with discreet whiplash and those with vestibular pathology associated with acoustic neuroma. The results support the SPNT test as a test of cervical afferent dysfunction. Further research into cervical JPE as a discreet test of cervical afferentation is warranted.