Many individuals who use tobacco will continue to smoke after a cancer diagnosis and throughout treatment, however the literature shows that many cancer patients are highly motivated to quite at this time. Continued smoking in cancer patients undergoing various treatments results in decreased treatment efficacy, potentially increased toxicity, reduced survival and increased risk of recurrence/second malignancy. This study aims to better understand cancer patient preferences for smoking cessation education. All new patients seen at Princess Margaret Cancer Centre between January 1 2014 and June 30 2015 were asked to complete the Combined Tobacco History Survey as part of standard new patient assessments. Smoking status, second hand smoke exposure, years smoked, family support, cessation preferences, demographic and tumour details were collected. Multivariable regression assessed factors associated with smoking cessation educational preferences. 9110 patients completed the survey. 1691 were current smokers (17%) of which 43% were female and median age was 57 years (range 18-95). 1238 (73%) were willing to consider quitting and 953 (56%) reported a readiness to quit next month. Smokers included in this analysis were being treated predominantly for head and neck (n=365; 21.6%), gastrointestinal (GI) (n=249; 14.7%), gynecological (n=224; 13.2%), lung (n=210; 12.4%), and genitourinary (GU) (n=196; 11.6%) cancers. Patients were most interested in pamphlets (n=421; 45%) followed by telephone support (n=372; 39%), speaking with a healthcare professional (n=279; 29%), website (n=137; 15%), support group (n=101; 11%) and speaking with successful former smokers (n=89; 9%). Younger patients (≤ 45 years) preferred receiving smoking cessation education over the telephone (50%; p<0.001), while older patients (46-65 years and >65 years) preferred smoking education to be provided in pamphlets (43% and 51% respectively; p=0.07). In multivariable analyses, older patients were more likely to prefer pamphlets than younger patients OR 1.11 (95% CI: 1.01-1.23; p=0.03). Sex and cancer site were not predictive of preference of education modality. Among cancer patients, older patients preferred to receive smoking cessation education through pamphlets and younger patients preferred the telephone. This highlights the importance of developing a tailored approach to smoking cessation for different cancer patient populations. These data provide an evidence base for future program development in cancer education. Further work is needed to determine the specific educational content required to maximally promote smoking cessation in cancer patients.