Abstract Background Parental phubbing refers to the degree to which parents reduce or ignore their interactions with their children while taking care of their smartphones. Today, it has become important to conduct studies to understand the effects of parental phubbing on adolescents, which is increasing globally. This study aims to evaluate the relationship between perceived parental phubbing and smartphone addiction as well as depression in adolescents. Methods In this cross-sectional study, 314 adolescents aged 10-18 years who applied to the general pediatrics outpatient clinics of a university hospital in Ankara, the capital of Türkiye, were included. The questionnaire form used for data collection consisted of questions about the sociodemographic information of the participants, ‘Perceived Parental Phubbing Scale’, ‘Kutcher Adolescent Depression Scale Short Form’, and ‘Smartphone Addiction Short Form for Adolescents’ items. Descriptive statistics, Mann Whitney U, Kruskal Wallis H test and Spearman correlation analysis were used to analyse the data. A value of p < 0.05 was considered statistically significant. Results Depression and smartphone addiction levels were found to be significantly lower in adolescents who did not smoke, engaged in regular physical activity and had a close group of friends (p < 0.05). It was also found that the level of perceived parental phubbing was significantly higher in adolescents whose parents’ education level was above high school and who felt lonely (p < 0.05). Low level positive correlations was found between perceived parental phubbing and both depression (r = 0.116, p = 0.041) and smartphone addiction (r = 0.128, p = 0.023). Conclusions As the level of parental phubbing perceived by adolescents increased, the levels of depression and smartphone addiction in adolescents increased. These negative effects of parental phubbing on adolescents should be taken into consideration by mental health professionals. Key messages • It is important to consider and question parental phubbing as one of the related factors in adolescents with high levels of smartphone addiction and depression. • There is a need for studies to increase the awareness of parents, who are important role models for adolescents, about the concept of phubbing and its effects on adolescents’ mental health.