In the construction of building structures, numerous components simultaneously experience axial pressure and lateral bending moments. This concurrent influence plays a pivotal role in structural design considerations. This paper presents an experimental investigation of the compression-bending performance of rubberized concrete-filled corrugated steel tubes (RuCFCST). Twenty-two specimens were tested to evaluate the effect of eccentricity, length-diameter ratio, and confinement factor on the failure mode, load-displacement response, stiffness, compression-bending capacity, and ductility of the columns. The study also conducted a stress analysis on the corrugated steel tube to understand its confinement effect on the core rubberized concrete. The results demonstrate that the confinement factor emerges as a pivotal and sensitive parameter that impacts the compression-bending bearing capacity of RuCFCST columns. The study further elucidated the non-uniform confinement and failure mechanisms of the RuCFCST column, and subsequently assessed the applicability of the specimen's compression-bending bearing capacity as calculated by current specifications. The proposed RuCFCST columns offer new insights and serve as a reference for developing composite member systems with large hoop stiffness, small wall thickness, and environmental sustainability.