Small-scale Robots Research Articles

Exploiting reprogrammable nonlinear structural springs for enhancing the manoeuvrability of a vibro-impact capsule robot

Vibro-impact capsule robots, propelled by rhythmic collisions of an internal mass triggered by an external magnetic field, are emerging as promising tools for minimally invasive surgery. This innovative actuation mechanism allows for delicate interaction with tissues, making them ideal candidates for navigating confined surgical spaces. However, their limited manoeuvrability and controllability remain significant hurdles, restricting their ability to navigate complex anatomies and perform precise interventions, ultimately hindering their broader clinical applications. This paper investigates the integration of reprogrammable structural springs in capsule robots, demonstrating how dynamic tuning can tailor the interaction between the inner mass and the capsule, thereby unlocking enhanced manoeuvrability and precise control of the capsule robot. A mathematical model describing the dynamic response of a vibro-impact capsule robot integrated with von Mises trusses (VMT), which are used to tailor the interaction between the inner mass and the capsule, is developed and verified using finite element modelling. Using the verified mathematical model, we explore how the transition between mono-stability and bi-stability of VMTs affects the capsule robot’s propelling performance. Our findings demonstrate that this state switch enables four distinct propulsion modes of the capsule robot. This work paves the way for a new paradigm in small-scale robot design by incorporating reprogrammable nonlinear structures. These structures empower the robots with unprecedented manoeuvrability and controllability within a compact, deployable form factor.

Design and batch fabrication of anisotropic microparticles toward small-scale robots using microfluidics: recent advances.

Small-scale robots with shape anisotropy have garnered significant scientific interest due to their enhanced mobility and precise control in recent years. Traditionally, these miniature robots are manufactured using established techniques such as molding, 3D printing, and microfabrication. However, the advent of microfluidics in recent years has emerged as a promising manufacturing technology, capitalizing on the precise and dynamic manipulation of fluids at the microscale to fabricate various complex-shaped anisotropic particles. This offers a versatile and controlled platform, enabling the efficient fabrication of small-scale robots with tailored morphologies and advanced functionalities from the microfluidic-derived anisotropic microparticles at high throughput. This review highlights the recent advances in the microfluidic fabrication of anisotropic microparticles and their potential applications in small-scale robots. In this review, the term 'small-scale robots' broadly encompasses micromotors endowed with capabilities for locomotion and manipulation. Firstly, the fundamental strategies for liquid template formation and the methodologies for generating anisotropic microparticles within the microfluidic system are briefly introduced. Subsequently, the functionality of shape-anisotropic particles in forming components for small-scale robots and actuation mechanisms are emphasized. Attention is then directed towards the diverse applications of these microparticle-derived microrobots in a variety of fields, including pollution remediation, cell microcarriers, drug delivery, and biofilm eradication. Finally, we discuss future directions for the fabrication and development of miniature robots from microfluidics, shedding light on the evolving landscape of this field.

Mitigating Singularities in Control of Magnetic Capsule Endoscopes Using a Novel Nested Electromagnetic Coil System

Magnetic actuation systems that utilize external electromagnetic coils present a promising approach for controlling untethered small-scale robots, notably in medical applications. However, these systems frequently experience actuation singularities at which robotic control over the agent is lost or severely diminished. Such singularities may lead to excessively large current or rapid current changes that significantly affect the robots’ stability in specific areas of the workspace. In order to effectively mitigate these actuation singularities, this paper introduces a closed-loop control method using a novel nested electromagnetic coil system, leveraging finite element analysis-based magnetic field data and a novel controller combining a singularity solver and optimal current control method. The electromagnetic system has 12 coils nested in four coil units, each having three concentric coils with different outer radius, surrounding a central workspace. We call the 12-coil system Variable Outer Radius Individually Addressable Coil Stacks (VORIACS). Here, we experimentally evaluate the method for closed-loop trajectory tracking of a soft magnetic capsule endoscope (PillCam™) and a permanent magnet robot inside the VORIACS system at different magnetic field orientations. The results demonstrate that the VORIACS system with a singularity solver reduces root mean square (RMS) position tracking errors of the PillCam™by 46% to 50% and orientation tracking errors by 41% to 42% compared to a standard 4-coil system. Moreover, the system can achieve a notable 60.73% reduction in RMS position error, with sub-millimeter precision control when controlling the permanent magnet robot. We further manipulate the PillCam™for tracking a medical application-inspired complex trajectory, showcasing the system’s potential in precise control of magnetic devices for medical use.

Hybrid Zwitterionic Hydrogels with Encoded Differential Swelling and Programmed Deformation for Small-Scale Robotics.

Stimuli-responsive shape-morphing hydrogels with self-healing and tunable physiochemical properties are excellent candidates for functional building blocks of untethered small-scale soft robots. With mechanical properties similar to soft organs and tissues, such robots enable minimally invasive medical procedures, such as cargo/cell transportation. In this work, responsive hydrogels based on zwitterionic/acrylate chemistry with self-healing and stimuli-responsiveness are synthesized. Such hydrogels are then judiciously cut and pasted to form hybrid constructs with predetermined swelling and elastic anisotropy. This method is used to program hydrogel constructs with predetermined 2D-to-3D deformation upon exposure to different environmental ionic strengths. Untethered soft robotic functionalities are demonstrated, such as actuation, magnetic locomotion, and targeted transport of soft and light cargo in flooded media. The proposed hydrogel expands the repertoire of functional materials for fabricating small-scale soft robots.

Enhancing the Mobility of Small-Scale Robots Via Nonlinear Structural Springs Exhibiting Negative Stiffness

Abstract Compared to traditional robotic systems, small-scale robots, ranging from several millimeters to micrometres in size, are capable of reaching narrower and vulnerable regions with minimal damage. However, conventional small-scale robots’ limited maneuverability and controlability hinder their ability to effectively navigate in the intricate environments, such as the gastrointestinal tract. Self-propelled capsule robots driven by vibrations and impacts emerge as a promising solution, holding the potentials to enhance diagnostic accuracy, enable targeted drug delivery, and alleviate patient discomfort during gastrointestinal endoscopic procedures. This paper builds upon our previous work on self-propelled capsule robots, exploring the potential of nonlinear connecting springs to enhance its propulsion capabilities. Leveraging a mathematical model for self-propelling robots with a von Mises truss spring, which is verified using a finite element model, we investigate the effects of negative stiffness and snap-back within the nonlinear structural spring on the robots’ propelling speed. Our analysis reveals that the negative stiffness of the von Mises truss can significantly reduce the sensitivity of the propelling speed to excitation frequency. As a result, the capsule robot exhibits a remarkably wider operational band where it maintains a high average propelling speed, surpassing its linear counterpart. This work sheds light on the potential for developing customized nonlinear structural systems for diverse scenarios in small-scale robot applications, opening up new possibilities for enhanced functionality and maneuverability in various biomedical applications.

Magnetic trap-based steering method for small-scale robots: Feasibility study

This paper proposes a novel method for steering a medical small-scale robot (SSR) based on a trapping magnetic field gradient (TMG). The proposed method steers a SSR in a desired direction by keeping and moving a SSR position via a TMG point changing. To create a TMG, a field-free point (FFP) is employed, and moreover a redefined FFP generation method is suggested to design a desired shape of a magnetic field map in a unidirectional mobile-type magnetic system with four electromagnetic coils. Herein, magnetic characteristics of a TMG were analyzed on a Multiphysics simulation and compared with previous methods for steering a SSR to confirm a TMG performance. Furthermore, the proposed method was implemented to validate a SSR steering ability in tubular environments. Consequently, the proposed method was verified by demonstrating a SSR targeting performance to a specific vascular branch via in-vitro experiments.

Small-scale robots inspired by aquatic interfacial biolocomotion

Small-scale robots inspired by aquatic interfacial biolocomotion

Learning-based intelligent trajectory planning for auto navigation of magnetic robots.

Introduction: Electromagnetically controlled small-scale robots show great potential in precise diagnosis, targeted delivery, and minimally invasive surgery. The automatic navigation of such robots could reduce human intervention, as well as the risk and difficulty of surgery. However, it is challenging to build a precise kinematics model for automatic robotic control because the controlling process is affected by various delays and complex environments. Method: Here, we propose a learning-based intelligent trajectory planning strategy for automatic navigation of magnetic robots without kinematics modeling. The Long Short-Term Memory (LSTM) neural network is employed to establish a global mapping relationship between the current sequence in the electromagnetic actuation system and the trajectory coordinates. Result: We manually control the robot to move on a curved path 50 times to form the training database to train the LSTM network. The trained LSTM network is validated to output the current sequence for automatically controlling the magnetic robot to move on the same curved path and the tortuous and branched new paths in simulated vascular tracks. Discussion: The proposed trajectory planning strategy is expected to impact the clinical applications of robots.

Three-degrees-of-freedom orientation manipulation of small untethered robots with a single anisotropic soft magnet

Magnetic actuation has been well exploited for untethered manipulation and locomotion of small-scale robots in complex environments such as intracorporeal lumens. Most existing magnetic actuation systems employ a permanent magnet onboard the robot. However, only 2-DoF orientation of the permanent-magnet robot can be controlled since no torque can be generated about its axis of magnetic moment, which limits the dexterity of manipulation. Here, we propose a new magnetic actuation method using a single soft magnet with an anisotropic geometry (e.g., triaxial ellipsoids) for full 3-DoF orientation manipulation. The fundamental actuation principle of anisotropic magnetization and 3-DoF torque generation are analytically modeled and experimentally validated. The hierarchical orientation stability about three principal axes is investigated, based on which we propose and validate a multi-step open-loop control strategy to alternatingly manipulate the direction of the longest axis of the soft magnet and the rotation about it for dexterous 3-DoF orientation manipulation.

Embodied, flexible, high-power-output, structural batteries for untethered, small-scale robots

Embodied, flexible, high-power-output, structural batteries for untethered, small-scale robots

A mucoadhesive magnetic millimeter-scale robot with two motion modes for drug delivery to the colon

The small-scale robots for targeted drug delivery are gradually attracting great interest, and increasing the residence time of robots in targeted areas is conducive to increasing bioavailability. A drug-loaded magnetic millimetre-scale robot that can bond to colonic mucosa has been developed. The main body of the robot is composed of two approximately rectangular Poly (lactic acid) (PLA) sheets perpendicular to each other. The magnetic disk and the drug-loaded adhesive film are symmetrically distributed at the tail sheet. The robot has two ways to move: swimming and rolling. A high-frequency-rotating magnetic field can drive it to swim in liquid environments, or a low-frequency-rotating magnetic field can drive it to roll in an air environment. The drug-loaded adhesion patch can attach to both PLA and mucosa, ensuring the bond to the robot during movement and maintaining mucoadhesion to the intestinal mucosa during drug release. The initial contact force applied by a magnet between the robot and the intestinal surface was calculated and measured. The adhesion functionality of the robot to porcine colon was proved in the vitro simulated adhesion experiment.

A Small-Scale Hopper Design Using a Power Spring-Based Linear Actuator.

Hopping locomotion has the potential to enable small-scale robots to maneuver lands quickly while overcoming obstacles bigger than themselves. To make this possible, in this paper, we propose a novel design of a high-power linear actuator for a small-scale hopper. The key design principle of the linear actuator is to use a power spring and an active clutch. The power spring provides a near constant torque along the wide range of output displacement. The active clutch controls the moving direction and operation timing of the linear actuator, which enables the hopper to take off at the right timing. As a result, the hopper has a size of 143 mm, a mass of 45.9 g, and hops up to 0.58 m.

Submillimeter Multifunctional Ferromagnetic Fiber Robots for Navigation, Sensing, and Modulation.

Small-scale robots capable of remote active steering and navigation offer great potential for biomedical applications. However, the current design and manufacturing procedure impede their miniaturization and integration of various diagnostic and therapeutic functionalities. Herein, submillimeter fiber robots that can integrate navigation, sensing, and modulation functions are presented. These fiber robots are fabricated through a scalable thermal drawing process at a speed of 4 meters per minute, which enables the integration of ferromagnetic, electrical, optical, and microfluidic composite with an overall diameter of as small as 250µm and a length of as long as 150m. The fiber tip deflection angle can reach up to 54o under a uniform magnetic field of 45 mT. These fiber robots can navigate through complex and constrained environments, such as artificial vessels and brain phantoms. Moreover, Langendorff mouse hearts model, glioblastoma micro platforms, and in vivo mouse models are utilized to demonstrate the capabilities of sensing electrophysiology signals and performing a localized treatment. Additionally, it is demonstrated that the fiber robots can serve as endoscopes with embedded waveguides. These fiber robots provide a versatile platform for targeted multimodal detection and treatment at hard-to-reach locations in a minimally invasive and remotely controllable manner.

A muscle-machine hybrid crawler: Omnidirectional maneuverability and high load capacity

Biohybrid robots actuated by living cells are promising candidates to develop a new generation of small-scale robots. However, realizing desirable traits of fast motion, agile actuation, and high load capacity are still challenging for the biohybrid robots because of inherent contraction limitation of living cells from mammalians in a small scale. To overcome it, we developed a centimeter-scale muscle-machine hybrid crawler actuated by gracilis minor tissue from bullfrogs with high levels of actuation performance. The gracilis minor tissues could generate large actuation (contractile force: ∼4.40 N, strain: ∼0.28), fast contraction (∼60 ms), long lifetime (> 118 h), and especially contraction direction controllability by electrical stimulation manipulation over the tissues, leading to flexible control of biohybrid robots independent from mechanical design, which surpassed existing living materials as bioactuators. The tissue based biohybrid crawler achieved large actuation (average speed: ∼4.80 mm/s; a continuous motion of ∼700 mm to exhaustion), agile maneuverability in 360 degrees by the contraction direction modulation of the tissue (7.82 º/s and 9.62 º/s for left and right rotation respectively), long-term actuation (∼168 h), and high load capacity (maximum load/actuator-weight ratio: ∼20; maximum speed: ∼8.90 mm/s). As a demonstration, we showed that our robots allowed free maneuvering under a load state. This study provides a platform to break through limitations in conventional biohybrid robots and paves a way to fulfill lifelike motions.

A Magnetic Millirobot Walks on Slippery Biological Surfaces for Targeted Cargo Delivery.

Small-scale robots hold great potential for targeted cargo delivery in minimally invasive medicine. However, current robots often face challenges in locomoting efficiently on slippery biological tissue surfaces, especially when loaded with heavy cargo. Here, we report a magnetic millirobot that can walk on rough and slippery biological tissues by anchoring itself on the soft tissue surface alternatingly with two feet and reciprocally rotating the body to move forward. We experimentally studied the locomotion, validated it with numerical simulations, and optimized the actuation parameters to fit various terrains and loading conditions. Furthermore, we developed a permanent magnet set-up to enable wireless actuation within a human-scale volume that allows precise control of the millirobot to follow complex trajectories, climb vertical walls, and carry cargo up to four times its own weight. Upon reaching the target location, it performs a deployment sequence to release the liquid drug into tissues. The robust gait of our millirobot on rough biological terrains, combined with its heavy load capacity, makes it a versatile and effective miniaturized vehicle for targeted cargo delivery.

Dipo: a miniaturized hopping robot via lightweight and compact actuator design for power amplification

Kangaroo rats are well known as representative hoppers in small-scale animals. Especially kangaroo rats show rapid movement when a predator approaches. If this amazing motion can be applied to small-scale robots, they will be able to traverse lands at high speed while overcoming size limitations. To take advantage of hopping locomotion, in this paper, we present a lightweight and small-scale clutch-based hopping robot called Dipo. To make this possible, a compact power amplifying actuation system has been developed using a power spring and an active clutch. The power spring is possible to take out and use the accumulated energy little by little whenever the robot starts to hop. Moreover, the power spring needs low torque to charge the elastic energy, and a only tiny space is required to install. The active clutch controls the motion of hopping legs by adjusting the timing of energy release and storage. Thanks to these design strategies, the robot weighs 45.07 g, has the height of 5 cm in the stance phase, and achieves the maximum hopping height of 54.9 cm.

Small-Scale Robotics with Tailored Wettability.

Small-scale robots (SSRs) have emerged as promising and versatile tools in various biomedical, sensing, decontamination, and manipulation applications, as they are uniquely capable of performing tasks at small length scales. With the miniaturization of robots from the macroscale to millimeter-, micrometer-, and nanometer-scales, the viscous and surface forces, namely adhesive forces and surface tension have become dominant. These forces significantly impact motion efficiency. Surface engineering of robots with both hydrophilic and hydrophobic functionalization presents a brand-new pathway to overcome motion resistance and enhance the ability to target and regulate robots for various tasks. This review focuses on the current progress and future perspectives of SSRs with hydrophilic and hydrophobic modifications (including both tethered and untethered robots). The study emphasizes the distinct advantages of SSRs, such as improved maneuverability and reduced drag forces, and outlines their potential applications. With continued innovation, rational surface engineering is expected to endow SSRs with exceptional mobility and functionality, which can broaden their applications, enhance their penetration depth, reduce surface fouling, and inhibit bacterial adhesion.

Automated group motion control of magnetically actuated millirobots

Small-size robots offer access to spaces that are inaccessible to larger ones. This type of access is crucial in applications such as drug delivery, environmental detection, and collection of small samples. However, there are some tasks that are not possible to perform using only one robot including assembly and manufacturing at small scales, manipulation of micro- and nano- objects, and robot-based structuring of small-scale materials. In this article, we focus on tasks that can be achieved using a group of small-scale robots like pattern formation. These robots are typically externally actuated due to their size limitation. Yet, one faces the challenge of controlling a group of robots using a single global input. In this study, we propose a control algorithm to position individual members of a group in predefined positions. In our previous work, we presented a small-scaled magnetically actuated millirobot. An electromagnetic coil system applied external force and steered the millirobots in various modes of motion such as pivot walking and tumbling. In this paper, we propose two new designs of these millirobots. In the first design, the magnets are placed at the center of body to reduce the magnetic attraction force between the millirobots. In the second design, the millirobots are of identical length with two extra legs acting as the pivot points and varying pivot separation in design to take advantage of variable speed in pivot walking mode while keeping the speed constant in tumbling mode. This paper presents an algorithm for positional control of n millirobots with different lengths to move them from given initial positions to final desired ones. This method is based on choosing a leader that is fully controllable. Then, the motions of other millirobots are regulated by following the leader and determining their appropriate pivot separations in order to implement the intended group motion. Simulations and hardware experiments validate these results.

Dynamic Production Line Re-balancing by Alternative Plans for Compensating Equipment Failures

As social uncertainty increases, there are changes in values such as safety, sustainability, and response to changes. The manufacturing industry is also required to improve its resilience by dynamically recombining production resources to respond to change. In the operation of a production line, if demand fluctuates due to changes in the external environment or customer needs, or if sudden production fluctuation such as equipment failure occurs, the production line will be stopped due to reconfiguration or equipment restoration. Therefore, the challenge is to continue production and improve productivity even when fluctuation occurs. In order to respond to the above challenges, this research aims to dynamically and quickly re-plan the production line using the existing equipment according to current equipment and production status. In this paper, failures of the production equipment, such as robots and tools, are regarded as production fluctuation factors. In order to continue production with the remaining resources in the event of equipment failure, it is necessary to change the process plan. However, since these are engineering tasks in the production preparation stage, there was the problem of not being able to flexibly change them at the manufacturing site during the production execution stage. In this development, an alternative plan pre-generation and selection method was developed to maintain production by re-allocating tasks during equipment failure. In this approach, first, multiple alternative plans for task allocation for failures in each piece of equipment are planned in advance using a process plan optimization technique. Next, production fluctuations due to equipment failures are detected. Finally, dynamic changes are possible by selecting alternative plans that maximize the throughput of the entire production system. Initial verification results are shown by comparison with the conventional method for equipment failure using simulation on a small-scale robot assembly line for automotive inverter.

Collective Behaviors of Active Matter Learning from Natural Taxes Across Scales.

Taxis orientation is common in microorganisms, and it provides feasible strategies to operate active colloids as small-scale robots. Collective taxes involve numerous units that collectively perform taxis motion, whereby the collective cooperation between individuals enables the group to perform efficiently, adaptively, and robustly. Hence, analyzing and designing collectives is crucial for developing and advancing microswarm toward practical or clinical applications. In this review, natural taxis behaviors are categorized and synthetic microrobotic collectives are discussed as bio-inspired realizations, aiming at closing the gap between taxis strategies of living creatures and those of functional active microswarms. As collective behaviors emerge within a group, the global taxis to external stimuli guides the group to conduct overall tasks, whereas the local taxis between individuals induces synchronization and global patterns. By encoding the local orientations and programming the global stimuli, various paradigms can be introduced for coordinating and controlling such collective microrobots, from the viewpoints of fundamental science and practical applications. Therefore, by discussing the key points and difficulties associated with collective taxes of different paradigms, this review potentially offers insights into mimicking natural collective behaviors and constructing intelligent microrobotic systems for on-demand control and preassignedtasks.