AbstractSurface‐enhanced Raman scattering (SERS) from ethylenediaminetetraacetic acid (EDTA, NaO2CCH2N(CH2CO2H)CH2CH2N‐(CH2CO2Na)CH2CO2H) on silver and copper electrodes is reported. There is no SERS spectrum observed for EDTA on copper electrodes. The SERS spectrum on silver is very dependent on electrolyte and laser power. In nitrate electrolyte, most of the bands typical of EDTA are observed in the SERS spectra with small wavenumber shifts and small relative intensity changes. In 0.1 mol/1 chloride electrolyte the SERS spectra show indication of decarboxylation and are nearly identical to SERS spectra of N,N,N′,N′‐tetramethylethylenediamine (TMEDA, (CH3)2NCH2CH2N(CH3)2). However, SERS spectra of TMEDA show evidence that TMEDA also reacts. SERS spectra of ethylenediamine‐N,N′‐diacetic acid show many similar bands to those found in the SERS spectra of TMEDA.