Seve Ballesteros-Santander Airport (SDR/LEXJ) is a success story among Europe’s small regional airports. This success is due, among other factors, to: 1) the commitment to the promotion of connectivity and tourism by the successive regional governments of Cantabria, one of the 17 regions making up Spain; 2) the management of the infrastructure carried out by Aena, with intense modernisation and expansion of the airport; and 3) the commitment of the airlines to Cantabria through the development of a large network of air routes, especially Ryanair, but also Air Nostrum, Vueling, Iberia, Volotea, Wizz Air and Binter. In the last 20 years, the airport’s traffic volume has quadrupled from 250.000 passengers to one million. The number of destinations has increased from just a few frequencies to Madrid and Barcelona to 30 destinations covering the whole of Spain and providing connectivity to the main European capitals and major cities. This paper will analyse some of the factors, including supply and demand, that have given rise to this success. It will also discuss the economic impact of the airport on the region and some of the main opportunities and challenges it will face throughout the coming years.