Small Incision Non-phacoemulsification Cataract Extraction Research Articles

The variation of corneal curvature of diabetic patients after small-incision extracapsular cataract extraction

Objective To analyse the variation of corneal curvature of diabetic patients after small incision non-phacoemulsification extracapsular cataract extraction. Methods The data of 83 eyes of 71 patients with cataract and diabetic from Apr.2009 to Apr.2012 were collected and all cases were divided into 3 groups: normal control group, diabetic groupⅠ(blood glucose<9.0 mmol/L) and diabetic groupⅡ(blood glucose≥9.0 mmol/ L). The follow-up time was 12 months. Results Horizontal corneal curvature (HCC) of the three groups after surgery were higher than that of before surgery, the difference was statistically significant (P<0.001). Vertical corneal curvature (VCC) after surgery were lower than that before surgery (P<0.001). The difference value of HCC in control group and diabetic groupⅠwere decreased 3 days-12 months after surgery (P<0.05). The difference value of HCC in diabetic groupⅡwas decreased from 3 days to 6 months after surgery (P<0.05), the difference value was not changed from 6 to 12 months after surgery (t=0.292, P=0.774). The difference value of VCC in control group and diabetic group Ⅱwere decreased 3 days-12 months after surgery (P<0.05). The difference value of VCC in diabetic groupⅠwas decreased 3 days-6 months after surgery (P<0.05), the difference value remained stable at 6-12 months after surgery (t=1.578, P=0.129). Conclusion HCC of the three groups are elevated and VCC are decreased, the degree of change is proportional to the level of blood glucose, the healing process of corneal acomplishes almost from half year to 1 year. Key words: Extracapsular cataract extraction, small-incision; Patient, diabetic; Corneal curvature

Efficacy of small incision non-phacoemulsification cataract extraction for the treatment of hard nucleus cataract

Objective To evaluate the efficacy of small incision non-phacoemulsification cataract extraction and intraocular lens implantation for the treatment of hard nucleus cataract. Methods The data of 198 eyes of 198 cases with hardness nucleus grades Ⅳ-Ⅴwere collected and they received small incision cataract extraction by manual nuclear fragmentation and implantation of intraocular lens. Results The eyes with best corrected visual acuity(BCVA) ≥0.5 accounted for 67.17% and BCVA≥1.0 for 36.36% 1 week after surgery.Three months after surgery the eyes of BCVA≥0.5 were in 93.43% and ≥1.0 in 75.76% .The astigmatism was (1.50 ± 0.75)D 1 week after surgery, and(0.75 ± 0.50)D 3 months after surgery .Postoperative complications were mild corneal edema in 19 eyes(9.60%), iritis in 13 eyes(6.57%), and posterior capsule mild turbidity in 14 eyes(7.07%). No serious complication occurred. Conclusion Small incision non-phacoemulsification cataract surgery is effective with low astigmatism, less complications and fast vision recovery .It avoides corneal injury caused by the ultrasonic energy. Key words: Cataract, hard nucleus; Cataract extraction, non-phacoemulsification, small incision

Expression and its significance of aquaporin0 and 1 in lens with age-related cataract

Background Age-related cataract is a common cause of blindness.However, its cause and pathogenic mechanism have not been fully understood.Recent studies revealed that aquaporin 1 (AQP1) and AQP0 are closely related to the pathogenesis of cataract. Objective This study was to investigate the differential distribution and expression of AQP0 and AQP1 in lenses with age-related cataract and explore its effect on pathogenesis of age-related cataract. Methods Seventeen anterior capsular membrane samples and nucleus samples of lenses were collected from age-related cataract patients during the small incision nonphacoemulsification cataract extraction, and 6 normal lens samples were obtained from health donors in the First Affiliated Hospital of Fujian Medical University.The expression and distribution of AQP1 and AQP0 in the lenses were detected by immunohistochemistry, and the relative expression levels of AQP1 and AQP0 proteins in the lenses were assayed by using Western blot assay.This study protocol was approved by Ethic Committee of this hospital, and written informed consent was obtained from each patient. Results Immunohistochemistry showed that in the normal lenses, AQP1 expressed mainly in LECs; while AQP0 primarily expressed in fiber cells of the lens cortex and nucleus.The relative expression levels of AQP1 and AQP0 in the lenses with age-related cataract (absorbance) were 0.223±0.008 and 0.118±0.015, which were significantly lower than 0.246±0.007 and 0.149±0.007 in the normal lenses (t=-4.508, -3.291, both at P<0.01). Western blot revealed that the relative expression levels of AQP1 and AQP0 in the lenses with age-related cataract (absorbance) were 0.663±0.012 and 0.599±0.015, which were significantly reduced in comparison with 0.844±0.041 and 0.955±0.064 in the normal lenses (t=-7.492, P<0.05; t=-9.570, P<0.01). Conclusions AQP1 and AQP0 distribute in different sites of lenses.The expressions of AQP1 and AQP0 are obviously down-regulated in lenses with age-related cataract, suggesting that AQP1 and AQP0 probably play different roles in the pathogenesis of age-related cataract. Key words: Aquaporin/metabolism; Lens, crystalline/metabolism; Eye proteins/metabolism; Water/metabolism; Cataract, age-related/pathogenesis; Humans; Cell membrane permeability/physiology

Small incision non-phacoemulsification cataract extraction

Objective To evaluate the efficacy of anti-eyebrow-shaped small scleral tunnel incision non-phacoemulsification cataract extraction and intraocular lens implantation.Methods The surgery was performed on 266 eyes of 266 patients that suffered from cataract.The follw-up period was 6-12 months.Results The best corrected visual acuities (BCVA) of 99 eyes (37.22％) were at ≥1.0 and the BCVA of 146 eyes (54.88％) were at 0.5-0.8.No serious complication was found.Conclusion Anti-eyebrow-shaped small scleral tunnel incision non-phacoemulsification cataract extraction and intraocular lens implantation have a good effect. Key words: Cataract, incision, small, scleral tunnel, anti-eyebrow-shaped; Lens, intraocular

Clinical study of improved small incision nonphacoemulsification in treatment of elderly patients with hard nucleus cataract

Objective To investigate the application of improved small incision nonphacoemulsification cataract extraction and intraocular lens implantation in senile cataract with hard nucleus.Methods 207 eyes of 163 cases of senile cataract underwent small incision nonphacoemulsification or phacoemulsification cataract extraction combined with intraocular lens implantation and the patients were followed up for 12 months.Based on the different procedures,the patients were divided into two groups:small incision nonphacoemulsification group (104 eyes of 82 cases) and phacoemulsification group (103 eyes of 81 cases).The time of surgery,the change of density and loss rate in corneal endothelial cells,and the vision of patients of the two groups were compared.Results The difference of operation time of two groups had no statistical significance(P ＞ 0.05).The changes of density and loss rate in corneal endothelial cells and the vision of patients in two groups were statistically significantly different (P ＜ 0.05).Conclusion Small incision nonphacoemulsification and intraocular lens implantation is a safe and effective surgical treatment for hard nucleus cataract. Key words: Cataract, extraction, improved, small incision, Nucleus, hard; Cells, endothelial,corneal

Autologous serum in the treatment of severe corneal epithelial shedding after cataract surgery

Objective To investigate the effect of autologous serum in the treatment of severe corneal epithelial shedding after cataract surgery.Methods 60 patients with severe corneal epithelial shedding after small incision non-phacoemulsification cataract extraction plus intraocular lens implantion were randomly divided into two groups.Autologous serum group received subconjunctival injections of autologous serum,autologous serum eye drops,and dextran and hypromellose eye drops four times daily; while the control group received dextran and dypromellose eye drops alone.The average healing time of the corneal epithelium was measured.Results The average healing time of the corneal epithelium was significantly shorter in the autologous serum group than in the control group ([12.90 ± 1.89]days vs.[26.00 ± 2.40]days,P＜0.01).Conclusions Autologous serum is efficacious in the treatment of severe corneal epithelial shedding after cataract surgery. Key words: Small incision non-phacoemulsification cataract surgery; Corneal epithelial shedding; Autologous serum

The improvement of small incision non-phacoemulsification cataract extraction

Objective To evaluate the clinical effects of cataract surgery through small incision non-phacoemulsification cataract extraction (SICS) and intraocular lens (IOL) implantation (SICS + IOL).Methods Indeatifying 6819 eyes of 5126 patients congenital cataracts,we used razor-blade to complete surgery steps such as the tunnel and incision,capsulorhexis arc.After surgery,the following-up from three months to nine years was carried out.Results After SICS + IOL,all of the eyes had slight uveitis,and few after-cataract,secondary glaucoma,retinal detachment and other complications.Conclusion This type of surgery has the advantages of small incision,sutureless,non-Sophisticated equipment needed and easily grasped,so it shoud be easily opened in the grassroots. Key words: Cataract extraction, small,incision ; Razor-blade; Lens, intraocular

Clinical observation of small incision non-phacoemuisification cataract extraction of 110 cases in Grassroots hospital

Objective To study if small incision non-phacoemulsification cataract extraction is suitable for primary hospitals.Methods Our hospital 110 cases(120 eyes),after small incision non-phacoemulsification cataract extraction combined with intraocular lens implantation in treatment of cataract patients data,the intraoperative,postoperative complications,and postoperative visual acuity recovery were summarized.Results Intraoperative,postoperative complications were compared with previous surgery,postoperative visual acuity recovered better faster.Conclusion Small incision non-phacoemulsification cataract surgery is safe and effective,simple,less investment,low cost,suitable for primary hospitals in cataract operation. Key words: Small incision; Cataract; Non-phacoemulsification; Primary hospital

The clinical observation of intraocular lens implantation in the patients of small-incision non-phacoemulsification cataract extraction with posterior capsule intraoperative rupture

Objective To study the efficacy and safety of non-phacoemulsification cataract extraction and intraocular lens implantation in the patients with intraoperative posterior capsule rupture. Methods 346 cases (381 eyes) were accepted small-incision non-phacoemulsification cataract surgery and were implanted intraocular lens. 21 cases underwent intraoperative posterior capsule rupture,of which 18 cases were accepted one-stage implantation of posterior chamber intraocular lens, 3 cases didn' t select it. The complications and postoperative visual acuity after follow-up for three months were investigated. Results Transient elevation of intraocular pressure occurred in 3 eyes ( 16. 67% ) , corneal edema in 16 eyes (88. 89% ) ,mild deviation of intraocular lens in 2 eyes ( 11. 11% ) , pupil less round and mild displacement in 5 eyes (27. 78% ). The best corrected visual acuity was more than 0. 5 in 13 eyes (72. 22% ) three months after operation. No serious complications occurred. Conclusion According to specific conditions, this technique of one-stage implantation of non-phacoemulsification intraocular lens is safe and can achieve better vision in the patients with intraoperative posterior capsule rupture during the surgery of non-phacoemulsification. Key words: non-phacoemulsification; small-incision; posterior capsular rupture; lens,intraocular

Surgeries for complicated cataract

Objective To observe the surgical methods and effect of the small incision non-phacoemulsification cataract extraction and intraocular lens implantation for complicated cataract. Methods The surgery was performed on 83 eyes of 62 patiens suffered from complicated cataract. The follow-up period was 6 - 18 months（ averaged 11.7 months）. Results The postoperative bestcorrected visual acuity of 24 eyes （28.92%） are better than 1.0 and 56 eyes（67.47% ） are better than 0.3. No serious complications were found. Conclusion Carefully observe, early dagnosis and correct treatment can reduce the complications and improve the vision for complicated cataract. Key words: complicated cataract ; small incision ; lens, artificial

The clinical application of small incision non-phacoemulsification cataract extraction and intraocular lens implantation

目的 探讨小切口非超声乳化白内障囊外摘出人工晶状体植人手术的临床效果.方法 对176例(189眼)施行小切口非超声乳化白内障囊外摘出人工晶状体植入手术.随访6-12月,平均9.5月.结果 术后最佳矫正视力≥1.0者86眼(45.50%),≥0.5者136眼(71.96%).无严重并发症发生.结论 小切口非超声乳化白内障手术安全、高效、操作简单、效果良好。

Temperal scleral manual extracapsular cataract extraction by small incision in patients after glaucoma surgery

目的 评价青光眼小梁切除术后经颞侧巩膜隧道小切口非超声乳化手法娩核囊外摘出术治疗白内障的手术方法和临床效果.方法 对38例42眼施行手术.常规球后麻醉.于颞侧角膜缘后2.0 mm行直线形或反眉形巩膜板层切开,长为5.5 mm,作隧道切口至透明角膜内1 mm.注入黏弹剂,行连续环行撕囊或开罐式截囊,直径6 mm,水分离后以旋转法将晶状体核旋入前房,以晶状体圈匙将核托出.以注吸针头吸净晶状体皮质.囊袋内植入人工晶状体.术中缩瞳.术后随访至少3月,观察视力、眼压、滤过泡等.结果 本组38例42眼术后第3天视力≥0.5者29眼(69.04%),术后眼压均在正常范围内,对原滤过泡无影响,未见严重并发症.结论 青光眼术后特别是上方小梁切除术后的白内障患者,经颞侧巩膜隧道式小切口进行手法娩核白内障手术切实可行,效果良好,值得向基层医院推荐。

The analysis on corneal edema after small-incision non-phacoemulsification cataract extraction

目的 探讨小切口非超声乳化白内障术后角膜水肿的原因及解决方法.方法对139例(163眼)小切口非超声乳化白内障囊外摘出(ECCE)或ECCE+PC-IOL术,分别观察术后1天、3天、1周角膜水肿情况,并将其按主要原因归类分析.结果术后第1天角膜水肿者103例123眼(75.46%);术后第3天仍水肿者12眼(7.36%);术后1周仍水肿者4眼(2.45%).角膜水肿的原因分析:因内切口靠前、娩核困难所致者70眼(42.94%);因灌注液压力过高时间长所致者41眼(25.15%);因暂时性眼压升高所致者6眼(3.68%);由于外伤性白内障术前角膜损伤所致者4眼(2.45%);由于后弹力层撕脱所致者及由于缩瞳剂所致者各1眼(各占0.61%).而水肿持续时间最长的原因是外伤性白内障术前原有角膜损伤和角膜后弹力层撕脱.结论小切口非超声乳化白内障囊外摘出术后角膜水肿的主要原因是内切口靠前、娩核困难,其次是术中高速度的液体冲洗。

A study on small incision non-phacoemulsification cataract extraction combined with intraocular lens implantation

目的 对比分析非超声乳化小切口白内障囊外摘出人工晶状体植入术与超声乳化吸出人工晶状体植入术的两种不同术式的效果.方法共95例(103眼)中非超声乳化小切口囊外摘出组37例(38眼),超声乳化组58例(65眼),对比观察两种术式的术后视力、散光及并发症.结果非超乳小切口白内障摘出术与超声乳化晶状体吸出术的术后视力、角膜散光及并发症差异无统计学意义.结论非超声乳化小切口白内障囊外摘出及人工晶状体植入术效果好、成本低、适合广大基层医院推广普及。

The operation of self-closing small incision non-phacoemulsification cataract extraction and intraocular lens implantation

目的 观察无缝线自闭小切口应用于非超声乳化白内障囊外摘出人工晶状体植入术的可靠性、快捷和安全性.方法对286例(317眼)施行自闭小切口非超声乳化白内障囊外摘出人工晶状体植入术.根据角膜曲率检查结果决定手术切口部位(上方、颞上方或颞侧).做以穹隆为基底球结膜瓣,做切口中心距角膜缘1mm的直线形或反眉形巩膜半层切口,长5.5～6.0mm,根据核硬度适当扩大切口,板层分离作角巩膜隧道,进入透明角膜1.5mm,用角膜刀入前房形成活瓣式内切口,内切口大于外切口,3:00或9:00时钟方位做透明角膜辅助切口,术毕切口水密自闭不缝合.结果术后3天视力≥0.5者276眼(占87%),术后1周视力0.5～1.0者301眼(占95%).随访3～12月,视力稳定.结论自闭切口免缝线,手术快捷、安全.术后并发症少、散光轻、视力恢复快而稳定。

Clinical analysis the complications of small incision nonphacoemulsification cataract extraction and intraocular lens implantation

目的 探讨小切口非超声乳化人工晶状体植入术并发症的发生和防治方法.方法观察76例(93眼)手术结果,随访2～24月.对术中、术后并发症及预后作了分析和讨论.结果术后1周矫正视力≥0.5者占72.04%.主要并发症有后囊破裂,虹膜损伤,角膜水肿等.结论本手术是基层医院一种有效的术式,早期因操作不当和经验不足可引起一些并发症。

A compare of vision results of phacoemulsification and small incision non-phacoemulsification cataract extraction and IOL implantation

目的 观察比较晶状体超声乳化吸出术与小切口非超声乳化白内障囊外摘出术的术后视力.方法将老年性白内障患者随机分2组,A组行晶状体超声乳化吸出术,B组行小切口非超声乳化白内障囊外摘出术,观察术后第1天、30天的视力.结果共观察230例,230眼.A组134眼,B组96眼.两组术后视力差异无显著意义(Uc=1.068,P＞0.05).结论 超声乳化吸出术与小切口非超声乳化白内障囊外摘出术的术后视力比较差异无显著意义。

The small incision non-phacoemulsification cataract extraction and IOL implantation

目的 探讨小切口非超声乳化人工晶状体植入术的临床效果和优点.方法76例(82眼)采用反弧形巩膜隧道切口摘出白内障植入后房型人工晶状体,并与65例(68眼)传统大切口手术进行对比.结果术后1周及2月随访观察:小切口组裸眼视力≥0.5者分别占56.1%和79.3%,平均散光为(1.92±1.02)D和(0.92±0.75)D;大切口组裸眼视力≥0.5者分别占34.0%和60.3%,平均散光为(4.56±1.52)D和(2.51±1.48)D,两组相比差异有显著性意义(P＜0.05).结论小切口手术组织损伤轻,术后视力恢复快、散光小,费用低廉。

Small incision non-phacoemulsification extracapsular cataract extraction combined with trabeculectomy in the tunnel

目的 探讨小切口隧道式非超声乳化白内障囊外摘出联合隧道切口内小梁切除术的可行性.方法青光眼合并白内障24例(26眼)行小切口隧道式非超声乳化囊外摘出联合隧道内的小梁切除术,观察术后视力及眼压变化情况.结果24例(26 眼)术后均形成弥散扁平型滤过泡,术后在不用降眼压药物的情况下眼压正常,平均眼压由术前的(26.86±9.46)mmHg(1 mmHg=0.133kPa)降至术后的(12.89±2.15)mmHg.视力亦均有不同程度提高,术中术后未见严重并发症.结论该联合手术术后眼压控制满意,视力恢复良好,操作简便,且无需缝合。