Small Donor Research Articles

Big bees spread disease: body size mediates transmission of a bumble bee pathogen.

Trait variation can have important consequences for the outcomes of species interactions. Even though some traits vary as much within species as across related species, models and empirical studies typically do not consider the role of intraspecific trait variation for processes such as disease transmission. For example, many pollinator species are in decline because of a variety of stressors including pathogens, but the role of intraspecific trait variation in mediating disease dynamics is rarely considered. For example, pollinator body size could affect pathogen transmission via differences in resistance, foraging behavior and physiology. We tested effects of body size on pollinator pathogen transmission using the common eastern bumble bee Bombus impatiens in field tents, introducing an infected "donor" microcolony of large or small workers with an uninfected average-sized "recipient" microcolony and allowing bees to forage for 9-16d. Small donor bees had nearly 50% higher infection intensity (cells/0.02 μL) than large donor bees, but large donor bees were twice as likely to transmit Crithidia bombi to recipient bees. Both behavioral and physiological mechanisms may underlie this apparent paradox. Compared to small bees, large bees foraged more and produced more feces; simulations showed that foraging and defecation rates together had stronger effects on transmission than did donor infection intensity. Thus, effects of bee size on contact rates and pathogen supply may play significant roles in disease transmission, demonstrating the multifaceted impacts of traits on transmission dynamics.

Designing and theoretical study of fluorinated small molecule donor materials for organic solar cells.

A recently synthesized photoactive donor named fluorinated thienyl-substituted benzodithiophene (DRTB-FT), modified with four novel end capped acceptor molecules, has been investigated through different electrical, quantum, and spectrochemical techniques for its enhanced electro-optical and photovoltaic properties. DRTB-FT was connected to 2-methylenemalononitrile (D-1), 2-methylene-3-oxobutanenitrile (D-2), 2-(2-methylene-3-oxo-2,3-dihydro-1H-inden-1-ylidene) malononitrile (D-3), and 3-methyl-5methylene-2-thioxothiazolidin-4-one (D-4) as terminal acceptor moieties. The architectural D-1 and D-3 molecules owe reduced optical band gap of 2.45 and 2.28 eV benefited from A-D-A configuration and have broaden maximum absorption band (λmax) at 617 and 602 nm in polar organic solvent (chloroform). Reduced optical band gap sets the ease for enhanced absorption. Reorganization energy of electron (λe) of D-3 molecule (0.00397 eV) was smaller among all which disclosed its greater mobility of conducting electrons (ICT). Larger values of dipole moment (μ) of D-1 (5.939 Debye) and D-3 (3.661 Debye) molecules in comparison to R indicated greater solubilities of the targeted molecules. Among the tailored molecules, D-3 showed the lowest binding energy of 0.25 eV in solvent phase and 0.08 eV in gaseous phase. The voltaic strength of the designed molecules was examined with respect to fullerene derivative (PC61BM) which exposed that D-1 is the best choice for achieving higher PCE. TDM (transition density matrix), DOS (density of states) analysis, and binding energies all were estimated at MPW1PW91/6-31G (d, p) level of DFT (density functional theory). All the architecture molecules show reduced band gap and high electron transfer rate due to the lowest reorganization energy (RE) of electron. The results show that there is greater contribution of acceptor and conjugated donor core towards the total absorption into the visible region of the spectrum. When tailored molecules D-1, D-2, D-3, and D-4 were blended with fullerene derivative polymer (PC61BM), they give high values of voltage at zero current level (Voc) compared to R.

Carbazole core derived dyes: New non-fullerene acceptor for all small-molecule organic solar cells with very high open-circuit voltage of 1.12 V

We have design and synthesized two similar A-π-D-π-A structured V-shaped small molecular non-fullerene acceptors named as BYG3 and BYG4 for BHJ-OSCs applications. The molecular architecture of BYG3 and BYG4 consists of an electron rich carbazole as central core, benzothiadiazole as π-spacer and finally it is end caped with naphthamide unit via ethyne linker. The major difference among BYG3 and BYG4 non-fullerene acceptors is fluorine atom substitution at benzothiadiazole unit and the effects of fluorine atom on its optical, electrochemical and photovoltaic properties were well discussed. The optoelectronic properties and band gap of BYG3 and BYG4 acceptors were well synchronized to small molecule donor SMD. Therefore, all small molecule BHJ-OSCs device were constructed using BYG3 and BYG4 as acceptors and small molecule (SMD) as donor results power conversion efficiency (PCE) of 8.09% and 8.57% with high open circuit voltages (Voc) of 1.12 V and 1.05 V respectively. Also, BYG4 based OSCs devices were displayed high values of short-circuit current density (Jsc) and fil factor (FF) are higher for than that for BYG3, may be related to the more effective exciton dissociation and charge transfer in the SMD:BYG4 active layer than that for SMD:BYG3 counterpart. However, the larger value of Voc for the BYG3 based OSCs than BYG4 counterpart may be related to the up-shifted LUMO energy level of BYG3.

An Audit of Lung Donor Pool: Optimal Current Donation Strategies and the Potential of Novel Time-Extended Donation After Circulatory Death Donation

In Australia, increased organ donation and subsequent lung transplantation (LTx) rates have followed enhanced donor identification, referral and management, as well as the introduction of a donation after circulatory death (DCD) pathway. However, the number of patients waiting for LTx still continues to exceed the number of lung donors and the search for further suitable donors is critical. All 2014-2018 Victorian DonateLife hospital deaths after intensive care unit (ICU) admission were analysed retrospectively to quantify unrecognised lung donors using current criteria, as well as novel time-extended (90 mins-24 hrs post-withdrawal) DCD lung donors. Using standard lung donor eligibility criteria, we identified 473 potential lung donors and a further 122 time-extended DCD potential lung donors among 3,538 patients meeting general eligibility criteria. Detailed review of end-of-life discussions with patient families and the reasons why they were not offered donation revealed several categories of additional lung donors-traditional lung donors missed in current practice (n=2); hepatitis C infected lung donors potentially treatable with direct-acting antivirals (n=14), time-extended DCD lung donors (n=60); donor lungs potentially suitable for transplant with use of ex-vivo lung perfusion (EVLP) (n=7). While the number of lung donor opportunities missed under existing DonateLife donor identification and management processes was limited, a time-extended DCD lung donation pathway could substantially expand the lung donor pool. The use of hepatitis C infected donors, and the possibility of EVLP to solve donor graft assessment or logistic issues, could also provide small additional lung donor opportunities.

P-75: Living Donor Intestinal Transplantation: A Valuable Strategy to Overcome the Shortage of Pediatric Small Bowel Donors

P-75: Living Donor Intestinal Transplantation: A Valuable Strategy to Overcome the Shortage of Pediatric Small Bowel Donors

Promising small molecule Pechmann dye analogue donors with low interfacial charge recombination for photovoltaic application: A DFT study

A series of donor–acceptor–donor (D-A-D) type small molecule (SM) donors containing Pechmann dye analogues (N, S, O) are designed and their geometrical, optoelectronic, charge transport, and photovoltaic properties are investigated using density functional theory (DFT). The structural modification of the donor backbone has been performed via additional sp2-nitrogen heteroatom incorporation in the Pechmann analogue acceptor cores. The N-heteroatom containing SM donors are found to be more air-stable due to having relatively deeper HOMO/LUMO levels than their unsubstituted counterparts. The maximum computed open-circuit voltage (Voc) is 1.53 V for the N-heteroatom substituted O-Pechmann core based donor. The designed donors are expected to harvest photon energy efficiently as their simulated absorption spectra lie in the visible region (575–724 nm). The N-heteroatom incorporation plays a significant role in lowering the charge recombination rate (KCR) and increasing the charge separation rate (KCS) at the SM donor/PC61BM interface. The ratio of interfacial KCS and KCR is found to be improved by 104−1010 times after sp2-nitrogen substitution in the Pechmann analogue cores. The maximum predicted power conversion efficiencies (PCEs) using the Scharber diagram reach up to ∼9% for the S-analogue of the Pechmann dye core based donor. This study sheds light on promising SM donors based on Pechmann dye analogues with low interfacial charge recombination rates and high charge separation rates and also demonstrates the impact of structural modification of Pechmann dye analogue cores on air-stability and overall photovoltaic performance.

Two star-shaped small molecule donors based on benzodithiophene unit for organic solar cells

Star-shaped small molecules have attracted great attention for organic solar cells (OSCs) because they have three-dimensional charge-transport characteristics, strong light absorption capacities and easily tunable energy levels. Herein, three- and four-armed star-shaped small molecule donors, namely BDT-3Th and BDT-4Th, respectively, have been successfully designed and synthesized, which used benzodithiophene (BDT) as the central unit. The two star-shaped intermediates (2a and 2b) could be simultaneously obtained by one-step of Suzuki coupling, and 1,2-dimethoxyethane played a key role in the Suzuki coupling. Both of them have excellent thermal stability, good solubility and broad absorption. Four-armed BDT-4Th shows a slightly higher extinction coefficient, a deeper HOMO energy level and an obviously better phase separation morphology when blended with Y6 than three-armed BDT-3Th. As a result, increased power conversion efficiency (PCE) of 5.83% is obtained in the BDT-4Th:Y6-based OSC devices, which is obviously higher than that of the BDT-3Th:Y6-based devices (PCE = 3.78%). To the best of our knowledge, this is the highest PCE among the BDT-based star-shaped donors-based OSCs. This result provides an effective strategy to obtain star-shaped small molecule donor materials for high efficient organic solar cells.

Successful single kidney transplantation from pediatric donors less than or equal to 10 kg to adult recipient: a retrospective cohort study.

BackgroundKidneys from very small pediatric donors (≤10 kg) are underutilized. Compared to en bloc kidney transplantation (EBKT), single kidney transplantation (SKT) can maximize donor resources. However, it remains unknown whether it’s appropriate to perform SKTs from donors weighing ≤10 kg.MethodsA total of 35 adult recipients undergoing kidney transplantation from donors weighing ≤10 kg at our center from December 2014 to December 2019 were included and grouped into SKT group (n=20) and EBKT group (n=15). Transplant outcomes were retrospectively analyzed and compared between 2 groups.ResultsThe 1-year and 3-year death-censored graft survival in SKT group was 95%, it is not significantly higher than that in EBKT group (80%, log-rank test, P=0.38). Significant improvement in estimated glomerular filtration rate (eGFR) was noted in both groups, despite eGFR at 1 year was lower in the SKT group (P<0.01). Proteinuria was common in both groups but subsided gradually during the follow-up time. Complication rates were similar between 2 groups with no vascular thrombosis in the SKT group.ConclusionsIn conclusion, SKTs from donors weighing ≤10 kg to adult recipients achieves comparable outcomes with EBKTs, which provides evidence to support performing SKTs from donors weighing ≤10 kg in certain donor and recipient scenarios.

Efficient Ternary Organic Solar Cells (>14%) Enabled By Non-Fullerene Acceptors

Organic Solar Cells (OSCs) fabricated from a ternary active layer, comprised of a mixture of either two electron donors and one acceptor or one donor and two acceptors, are presently at the vanguard of competitive OSCs affording an increased PCE when compared to binary counterparts.In this presentation, we´ll show our last work in ternary OSCs using two small molecule donors or two electron acceptors reaching efficiencies as high as 14%.References Privado, P. Malhotra, P. de la Cruz, R. Singhal, J. Cerdá, J. Aragó, E. Ortí, G. D. Sharma, F. Langa. Solar RRL 2020, 4, 1900471.G. Guijarro, P. Malhotra, G. Gupta, R. Caballero, P. de la Cruz, R. Singhal, G. D. Sharma, F. Langa. J. Mater. Chem. C, 2020, 8, 4763.G. Guijarro, R. Caballero, P. de la Cruz, R. Singhal, F. Langa, G.D. Sharma. Solar RRL 2020, 4, 2000460.Privado, P. de la Cruz, G. Gupta, R. Singhal, G. D. Sharma, F. Langa Solar Energy 2020, 199, 530.Rodríguez-Seco, L. Cabau, M. Privado, P. de la Cruz, F. Langa, G. D. Sharma, E. Palomares. ACS App. Energy. Mater. 2020. DOI: 10.1021/acsaem.0c02469

The glucagon-like peptide 1 receptor agonist Exendin-4 induces tenogenesis in human mesenchymal stem cells

Tendon injuries are common and account for up to 50% of musculoskeletal injuries in the United States. The poor healing nature of the tendon is attributed to poor vascularization and cellular composition. In the absence of FDA-approved growth factors for tendon repair, engineering strategies using bioactive factors, donor cells, and delivery matrices to promote tendon repair and regeneration are being explored. Growth factor alternatives in the form of small molecules, donor cells, and progenitors offer several advantages and enhance the tendon healing response. Small drug molecules and peptides offer stability over growth factors that are known to suffer from relatively short biological half-lives. The primary focus of this study was to assess the ability of the exendin-4 (Ex-4) peptide, a glucagon-like peptide 1 (GLP-1) receptor agonist, to induce tenocyte differentiation in bone marrow-derived human mesenchymal stem cells (hMSCs). We treated hMSCs with varied doses of Ex-4 in culture media to evaluate proliferation and tendonogenic differentiation. A 20 nM Ex-4 concentration was optimal for promoting cell proliferation and tendonogenic differentiation. Tendonogenic differentiation of hMSCs was evaluated via gene expression profile, immunofluorescence, and biochemical analyses. Collectively, the levels of tendon-related transcription factors (Mkx and Scx) and extracellular matrix (Col-I, Dcn, Bgn, and Tnc) genes and proteins were elevated compared to media without Ex-4 and other controls including insulin and IGF-1 treatments. The tendonogenic factor Ex-4 in conjunction with hMSCs appear to enhance tendon regeneration.

Designing and theoretical characterization of benzodithiophene dione based donor molecules for small molecule organic solar cells

A series of novel A1-A2-D-A2-A1 type four small donor molecules named SM1-SM4 have been designed based on a common dual accepting benzodithiophene dione unit. These donor molecules were designed by replacing end-capped (rhodanine) acceptors of already synthesized SBDT-BDD (reference R) molecule with 2-methylenemalononitrile (A1a) forming SM1, methyl 2-cyanoacrylate (A1b) forming SM2, 2-(3-oxo-2,3-dihydro-1H-inden-1-ylidene) malononitrile (A1c) forming SM3 and 1,4-dimethyl-5-methylene-2,6-dioxo-1,2,5,6-tetrahydropyridine-3-carbonitrile (A1d) forming SM4 molecule. The geometry optimization and theoretical characterization were carried out using reliable DFT at hybrid CAM-B3LYP/6–31G (d,p) level of theory. The photophysical, opto-electronic and wavelength dependent parameters of newly structured donors were computed and their resulting charge mobilities, maximum absorptions as well as exciton dynamics have been well addressed with respect to SBDT-BDD reference. Amongst all, SM3 exhibited maximum absorption at 484.2 nm due to its lowest energy bandgap (4.14 eV). It also exhibited lowest values of first singlet transition energy (2.56 eV), oscillator strength (1.01) and exciton binding energy (0.48 eV) because of its functionalization with strong electron withdrawing group (A1c). Moreover, the higher dipole moments, comparable hole and electron mobilities and higher values of Voc of SM1 and SM4 than R indicate the worth of these molecules being utilized as efficient donors in future OSC’s.

Triplet‐Charge Annihilation in a Small Molecule Donor: Acceptor Blend as a Major Loss Mechanism in Organic Photovoltaics

AbstractOrganic photovoltaics (OPV) are close to reaching a landmark 20% device efficiency. One of the proposed reasons that OPVs have yet to attain this milestone is their propensity toward triplet formation. Herein, a small molecule donor, DRCN5T, is studied using a variety of morphology and spectroscopy techniques, and blended with both fullerene and non‐fullerene acceptors. Specifically, grazing incidence wide‐angle X‐ray scattering and transient absorption, Raman, and electron paramagnetic resonance spectroscopies are focused on. It is shown that despite DRCN5T's ability to achieve OPV efficiencies of over 10%, it generates an unusually high population of triplets. These triplets are primarily formed in amorphous regions via back recombination from a charge transfer state, and also undergo triplet‐charge annihilation. As such, triplets have a dual role in DRCN5T device efficiency suppression: they both hinder free charge carrier formation and annihilate those free charges that do form. Using microsecond transient absorption spectroscopy under oxygen conditions, this triplet‐charge annihilation (TCA) is directly observed as a general phenomenon in a variety of DRCN5T: fullerene and non‐fullerene blends. Since TCA is usually inferred rather than directly observed, it is demonstrated that this technique is a reliable method to establish the presence of TCA.

A field experiment on fundraising to support independent information

Voluntary contributions solicited via fundraising campaigns can be a useful tool to finance high quality and independent news media without restricting readership, thus guaranteeing maximum diffusion. We conduct a field experiment with the Italian online information site lavoce.info to explore what type of message is more effective in eliciting readers’ willingness to contribute. We compare messages stressing the public good component of financing news or private benefits for donors. In addition, we test the effect on donations of including information about the tax allowance associated with contributions. While stressing the public good or private benefit component of donating to a media outlet does not lead to a statistically significant difference in terms of revenues raised, information about tax allowance reduces overall contributions, due to a reduction in the number of (small) donors.

Molecular packing modulation enabling optimized blend morphology and efficient all small molecule organic solar cells

The molecular planarity of a small molecule donor is one of the key factors affecting its molecular packing behavior, the morphology of the related active blend and thus the photovoltaic properties of all small molecule organic solar cells (ASM-OSCs). In this contribution, a series of new benzodithiophene (BDT)-based A-π-D-π-A type small molecules were developed, namely SD1, SD2 and SD3, by combining the chemical modification of side chain (sulfuration), π-bridge (alkoxy groups introducing) and end group (different type or different alkyl chain). The sulfuration of the BDT side chains and introducing alkoxy group to the π-bridge could induce intermolecular S⋯S and intramolecular S⋯O non-covalent interactions for higher planarity of these small molecules. The rhodanine and cyanoacetate end groups showed less effect on the optical and electronic properties but significantly affected the molecular packing behavior and blend morphology. From SD1:Y6-T to SD2:Y6-T and SD3:Y6-T, the face-to-face packing was gradually reduced, while the face-to-edge packing was increased, which resulted in lowered exciton dissociation efficiency, further decreased the device performance. SD1:Y6-T blend exhibited more favorable face-to-face packing and ideal morphology for efficient charge dissociation and transport, contributing to a champion PCE of 10.12%. This work provided a deep insight of the donor and acceptor packing behavior effect on the photovoltaic property by molecular design.

Small Donor Contributions in Response to Email Outreach by a Political Campaign

This research examines variation in response to mass email communications by a large and sophisticated political campaign over the course of the 2018 election cycle. Computational text analysis is utilized to generate and catalogue the most frequent themes across a body of 690 separate email messages. We find open rates vary somewhat by the subject key words of messages as well as when they were sent. In addition, small donations received through email are also responsive to the contents of messages, controlling for timing and other relevant factors. Given the very low cost associated with using email to communicate with supporters, it appears to be an effective means for harvesting small contributions and of providing opportunities for large numbers of voters to elevate their level of participation in the electoral process.

Organic J-Aggregate Nanodots with Enhanced Light Absorption and Near-Unity Fluorescence Quantum Yield.

Development of biocompatible fluorophores with small size, bright fluorescence, and narrow spectrum translate directly into major advances in fluorescence imaging and related techniques. Here, we discover that a small donor–acceptor–donor-type organic molecule consisting of a carbazole (Cz) donor and benzothiazole (BT) acceptor (CzBTCz) assembles into quasi-crystalline J-aggregates upon a formation of ultrasmall nanoparticles. The 3.5 nm CzBTCz Jdots show a narrow absorption spectrum (fwhm = 27 nm), near-unity fluorescence quantum yield (ϕfl = 0.95), and enhanced peak molar extinction coefficient. The superior spectroscopic characteristics of the CzBTCz Jdots result in two orders of magnitude brighter photoluminescence of the Jdots compared with semiconductor quantum dots, which enables continuous single-Jdots imaging over a 1 h period. Comparison with structurally similar CzBT nanoparticles demonstrates a critical role played by the shape of CzBTCz on the formation of the Jdots. Our findings open an avenue for the development of a new class of fluorescent nanoparticles based on J-aggregates.

DFT molecular modeling studies of D-π-A-π-D type cyclopentadithiophene-diketopyrrolopyrrole based small molecules donor materials for organic photovoltaic cells

A novel six D-π-A-π-D type compounds containing small molecules from cyclopentadithiophene (CPDT) and diketopyrrolopyrrole building (DPP) units were designed, as donors, for improving the efficiency of bulk hetero-junction solar cells. The geometries of the title compounds were optimized using the density functional theory at the hybrid functional B3LYP in combination with the 6−311 g(d,p) basis set. Electronic structures, photo-physical, optical and intra-molecular charge transfer properties have been investigated. The contour plots of the transition density matrix have been simulated for all compounds and used to evaluate the hole-electron localization, the donor-acceptor interaction as well as the electronic excitation processes in their excited states. The new designed donors have shown a large absorption in the visible range with interesting hole transport properties, resulted from their rigid-planar structures. The open circuit voltage and the fill factor were estimated. The present computational study showed that tuning the building blocks of the organic materials dispose a potential approach for further enhance the performance of small molecules donor materials in bulk hetero-junction (BHJ) organic solar cells.

Energy levels in dilute-donor organic solar cell photocurrent generation: A thienothiophene donor molecule study

To investigate photocurrent generation mechanisms in these organic solar cells (OSCs), we design and synthesize four thienothiophene (TT)-based small-molecule donors with the highest occupied molecular orbital (HOMO) levels varying from −6.4 eV to −5.1 eV, which span across the HOMO value of the [6,6]-phenyl-C70-butyric acid methyl ester (PC 71 BM) acceptor. We measure TT-based donor:PC 71 BM films’ electronic and optical properties, OSC current density-voltage characteristic, and external quantum efficiency, and perform density functional theory (DFT) calculations. Our results show that photocurrent generation depends strongly on the substitutions of the center TT groups, cyano (-CN) versus hexyloxy (-OHex). With 1 wt% donor, TTOHex:PC 71 BM devices produce seven times, increasing to twelve times for 5 wt % donor, higher photocurrent than neat PC 71 BM devices. In contrast, TTCN:PC 71 BM devices do not generate additional photocurrent even with 10 wt% donor. The photocurrent generation in TT-based donor:PC 71 BM devices depends critically on the HOMO value of the donor molecule with respect to that of PC 71 BM, indicating the importance of type II energy level alignment to facilitate exciton dissociation at the donor-acceptor interface. The photovoltage of all TT:PC 71 BM devices are comparable to neat PC 71 BM devices, 0.85–0.90 V, with a low voltage loss due to non-radiative recombination. The fill factor of TTOHex:PC 71 BM devices are low due to the low hole mobility, ~10 −8 cm 2 /V. Following exciton dissociation, hole transport is analyzed according to three possible mechanisms: tunneling, percolation pathways, and hole back transfer. We find that the hole back transfer mechanism can explain all experimental results and therefore is the primary hole transport mechanism for photocurrent generation in TT-based donor:PC 71 BM dilute-donor OSCs. • Design and synthesis of thienothiophene (TT)-based small molecule donors with varied HOMO levels. • Functional group substitutions on center TT groups have stronger effect on energy levels and photocurrent generation. • Favorable HOMO offset between donor and acceptor is required for exciton dissociation. • Hole back transfer is the primary hole transport mechanism for photocurrent generation in the TT:PCBM dilute-donor devices.

Synergistically minimized nonradiative energy loss and optimized morphology achieved via the incorporation of small molecule donor in 17.7% efficiency ternary polymer solar cells

To further improve the photovoltaic performance of the polymer solar cells (PSCs), it is an essential and significantly challenging issue to synergistically minimize non-radiative energy loss and optimize morphology. In this work, ternary PSCs are fabricated by incorporating a small molecule donor, namely BTTzR, into the state-of-the-art PM6:Y6 binary system. Detailed investigations suggest that BTTzR can form energy cascade with binary components to facilitate charge transfer. Furthermore, the integration of BTTzR can enhance crystallization and domain purity of the binary blend, and effectively suppress the aggregation of Y6, which ultimately leads to more efficient charge transport and lower non-radiative energy loss (ΔEnr). As a result, compared to the binary devices with PCE of 15.8% and ΔEnr of 0.23 eV, the ternary PSCs with 20% BTTzR contents achieved a significantly enhanced performance with PCE of 17.7% and lower ΔEnr of 0.19 eV, which are among the best results reported in the literatures to date. Therefore, this work not only offers a high-efficiency ternary blend system but also provides an efficient strategy to synergistically minimize non-radiative energy loss and optimize the morphology for the development of PSCs.

Suppressing Kinetic Aggregation of Non‐Fullerene Acceptor via Versatile Alloy States Enables High‐Efficiency and Stable Ternary Polymer Solar Cells

AbstractDespite considerable advances devoted to improving the operational stability of organic solar cells (OSCs), the metastable morphology degradation remains a challenging obstacle for their practical application. Herein, the stabilizing function of the alloy states in the photoactive layer from the perspective of controlling the aggregation characteristics of non‐fullerene acceptors (NFAs), is revealed. The alloy‐like model is adopted separately into host donor and acceptor materials of the state‐of‐the‐art binary PM6:BTP‐4Cl blend with the self‐stable polymer acceptor PDI‐2T and small molecule donor DRCN5T as the third components, delivering the simultaneously enhanced photovoltaic efficiency and storage stability. In such ternary systems, two separate arguments can rationalize their operating principles: (1) the acceptor alloys strengthen the conformational rigidity of BTP‐4Cl molecules to restrain the intramolecular vibrations for rapid relaxation of high‐energy excited states to stabilize BTP‐4Cl acceptor. (2) The donor alloys optimize the fibril network microstructure of PM6 polymer to restrict the kinetic diffusion and aggregation of BTP‐4Cl molecules. According to the superior morphological stability, non‐radiative defect trapping coefficients can be drastically reduced without forming the long‐lived, trapped charge species in ternary blends. The results highlight the novel protective mechanisms of engineering the alloy‐like composites for reinforcing the long‐term stability of NFA‐based ternary OSCs.