Small Channels Research Articles

Comprehensive Review of Inner Ear Anatomy on Photon-Counting CT.

The inner ear contains many fissures and canals that can mimic pathology. Photon-counting CT allows greater spatial and contrast resolution of these structures over traditional energy-integrating CT detectors. Small channels containing nerves, arteries, and normal anatomy such as the cochlear cleft and cochlear and vestibular aqueducts are commonly encountered on temporal bone imaging. The improved visualization of these structures poses challenges for radiologists who are new to photon-counting CT. This article updates the existing temporal bone anatomy literature with a detailed anatomic review of the inner ear and major nerves frequently encountered when reviewing temporal bone imaging.

Morphometric analysis and watershed delineation of the Karnaphuli river basin: A comparative study using different DEMs in Chittagong, Bangladesh

AbstractThe present study aimed to delineate a robust watershed boundary and extract its morphometric parameters in the Karnaphuli watershed, Bangladesh, using different digital elevation models (DEMs). Two DEMs, the shuttle radar topographic mission (SRTM) and the terra advanced spaceborne thermal emission and reflection radiometer (ASTER), were employed to delineate watershed boundaries and evaluate various morphometric characteristics. Raster data such as fill sinks, flow direction, and flow accumulation were utilized to delineate the watershed. The morphometric analysis included the estimation of linear, areal, and relief parameters. The findings revealed a noticeable difference between the datasets; ASTER delineated a larger watershed area than SRTM. Regarding stream order, there were streams ranging from 1st to 6th order, encompassing numerous small, medium, and main channels of the river. Drainage density was calculated as 0.52 km/km² for SRTM and 0.51 km/km² for ASTER, both having a spatial resolution of 30 m. The bifurcation ratio ranged from 1.94 for SRTM to 2.45 for ASTER, indicating varying degrees of structural disturbance influenced by geological factors. The form factor indicated an elongated shape of the study area. The overall dimensions of the streams and the watershed extent suggest moderate mean annual rainfall discharge. The watershed exhibited relatively high denudation rates, attributed to the basin relief. A low drainage density indicated the importance of infiltration processes. The findings of this study provide valuable insights into the spatial variability of watershed characteristics, highlighting the need for tailored management strategies for the Karnaphuli River. Implementing targeted conservation measures and watershed management practices based on these morphometric parameters can enhance water resource sustainability and ecological health in the region.

Uranyl–Nickel(II) Cation–Cation Interaction in a Triperiodic Framework with cis‐1,2‐Cyclohexanedicarboxylate and Isonicotinate Ligands

Uranyl and nickel(II) nitrates have been reacted with cis‐1,2‐cyclohexanedicarboxylic (H2chdc) and isonicotinic (Hint) acids under solvo‐hydrothermal conditions, giving the heterometallic, mixed‐ligand complex [(UO2)2Ni(chdc)2(int)2]⋅CH3CN (1). The uranyl cation is bound to carboxylate groups of both ligands while NiII is attached to two carboxylate and two nitrogen donors, with two strong additional interactions with uranyl oxo groups giving a nearly regular octahedral environment. The short Ni–O(oxo) bond length of 2.114(3) Å amounts to 67% of the sum of van der Waals radii. The trimetallic (UO2)2Ni6+ clusters thus formed are assembled by chdc2– ligands into linear chains which are further bridged by int– links to give a triperiodic framework with the dia topology, in which small channels encompass two rows of acetonitrile solvent molecules. Complex 1 does not display uranyl luminescence under excitation in the solid state.

A sexually dimorphic signature of activity-dependent BDNF signaling on the intrinsic excitability of pyramidal neurons in the prefrontal cortex

Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders with strong genetic heterogeneity and more prevalent in males than females. We and others hypothesize that diminished activity-dependent neural signaling is a common molecular pathway dysregulated in ASD caused by diverse genetic mutations. Brain-derived neurotrophic factor (BDNF) is a key growth factor mediating activity-dependent neural signaling in the brain. A common single nucleotide polymorphism (SNP) in the pro-domain of the human BDNF gene that leads to a methionine (Met) substitution for valine (Val) at codon 66 (Val66Met) significantly decreases activity-dependent BDNF release without affecting basal BDNF secretion. By using mice with genetic knock-in of this human BDNF methionine (Met) allele, our previous studies have shown differential severity of autism-like social deficits in male and female BDNF+/Met mice. Pyramidal neurons are the principal neurons in the prefrontal cortex (PFC), a key brain region for social behaviors. Here, we investigated the impact of diminished activity-dependent BDNF signaling on the intrinsic excitability of pyramidal neurons in the PFC. Surprisingly, diminished activity-dependent BDNF signaling significantly increased the intrinsic excitability of pyramidal neurons in male mice, but not in female mice. Notably, significantly decreased thresholds of action potentials were observed in male BDNF+/Met mice, but not in female BDNF+/Met mice. Voltage-clamp recordings revealed that the sodium current densities were significantly increased in the pyramidal neurons of male BDNF+/Met mice, which were mediated by increased transcriptional level of Scn2a encoding sodium channel NaV 1.2. Medium after hyperpolarization (mAHP), another important parameter to determine intrinsic neuronal excitability, is strongly associated with neuronal firing frequency. Further, the amplitudes of mAHP were significantly decreased in male BDNF+/Met mice only, which were mediated by the downregulation of Kcnn2 encoding small conductance calcium-activated potassium channel 2 (SK2). This study reveals a sexually dimorphic signature of diminished activity-dependent BDNF signaling on the intrinsic neuronal excitability of pyramidal neurons in the PFC, which provides possible cellular and molecular mechanisms underpinning the sex differences in idiopathic ASD patients and human autism victims who carry BDNF Val66Met SNP.

Viscoelastic liquid flow dynamics in small porous-medium channels under pressure and velocity forces

Viscoelastic liquid flow dynamics in small porous-medium channels under pressure and velocity forces

From the Northern Hajar Foothills to the Batinah Coast – a Geoarchaeological Survey at Saham and Dahwa (Northern Oman)

This geoarchaeological survey was dedicated to (i) the Umm an-Nar (2700–2000 BCE) settlement site of Dahwa and surrounding areas in the foothills of the Hajar Mountains as well as (ii) the coastal area near Saham on the Batinah coastal plain in northern Oman, the latter without focus on a specific cultural epoch. Stratigraphic sections from the proximal coastal plain provide insights into highly dynamic episodic sedimentation patterns with thick units of variable grain sizes and sorting. In one of the stratigraphic profiles in the town of Saham, a small anthropogenic pit or channel was found, interpreted as a pit hearth used by the Samad culture (300 BCE–100/200 CE) based on granulometry, thin-section analysis, clustered macro-charcoals, amorphous organic remains, as well as luminescence and 14C dating. Our coincidental discovery of this site indicates that there might be abundant traces of the Samad culture buried in the thick alluvium, from a period of hydrologically favourable conditions c. 50–300 CE. The Umm an-Nar dating of the Dahwa archaeological site in the foothills of the Hajar Mountains was confirmed for the first time by luminescence dating, although the low dose rate and high scatter of equivalent doses pose substantial challenges to the regional application of this method.

Compressibility effects in microchannel flows between two-parallel plates at low reynolds and mach numbers: Numerical analysis

Under certain circumstances, flow in microchannels can exhibit compressibility effects even at Reynolds numbers (Re) around (below 2,300) and low Mach numbers (below 0.3). This is particularly true for gases, especially when the flow undergoes significant pressure changes or acceleration within the microchannel. This study investigates the compressibility effects encountered in two-parallel plates microchannels at these low Reynolds and Mach numbers, due to the high-pressure drop associated with the small scale of the microchannels. This uncommon flow is characterized by an exceptionally small channel diameter-to-length aspect ratio (∼10–3), resulting in a friction coefficient that deviates from the typical value for laminar flow between parallel plates (f = 96/Re). Both steady and transient effects on the flow field are examined under low Re subsonic flow, assuming continuum behavior. The ideal gas equation is used to model gas density, while the isothermal Tait-Murnaghan equation models liquid density. For gases, compressibility effects are observed primarily when the inlet pressure ratio exceeds 0.1. The results show that these effects are less pronounced for liquids, even at elevated inlet pressure ratios. Additionally, a flow delay across the channel exhibits a first-order transient response. For liquid flow, this effect depends on the channel resistance, the total fluid volume within the channel, and the liquid's bulk properties, rather than the inlet pressure ratio.

Whole-channel acoustic energy and acoustophoretic efficiency frequency spectrum by the in-flow focusing method

The in-flow focusing method, introduced herein, enables rapid and straightforward measurements of the whole-channel acoustic energy of acoustic flow-through devices. The method is applied to assess the whole-channel acoustic energy and acoustophoretic efficiency frequency spectra of a bottom-actuated silicon-glass and a side-actuated glass chip. The input variables are the time-independent geometrical shape of the particle trajectories along the manipulation chamber, the channel cross-section geometry, the physical properties of the reference particles and fluid, and the volumetric flowrate. The outputs are the total acoustic energy, the acoustophoretic efficiency, as well as the acoustic energy density distribution along the channel, which provide a comprehensive overview of the performance of acoustically driven lab-on-a-chip setups. The acoustophoretic efficiency is an important parameter that relates the energy dissipation, and therefore the heat development in the device, to the useful acoustic energy in the channel. Unlike the current state-of-the-art methods such as particle image velocimetry, particle tracking velocimetry, and optical trapping, which are typically limited to small channel areas and are time-consuming, the in-flow focusing method can be applied to long channels and enables rapid measurements of the whole-channel acoustic energy. Published by the American Physical Society 2024

Improving broadband absorption of carbon dot conjugated melanin via pre-doping strategy as interfacial photothermal evaporator

Photothermal seawater desalination harnesses solar energy to induce heat and expediates seawater evaporation and purification. The desalination efficacy heavily relies on the light absorption capability and microstructure of the solar evaporator. Polydopamine (PDA) represents a typical synthetic melanin with broad spectral absorption characteristics. However, its absorption capacity within the near-infrared (NIR) region is limited, leading to inadequate photothermal conversion efficiency. To overcome this challenge, we adopt a straightforward approach involving the pre-doping of N,S-doped carbon quantum dots (N,S-CQDs) with dopamine through covalent interaction to fabricate CQDs-loaded mesoporous polydopamine (MPDA-8). This strategy effectively reduces the band gap of PDA by fostering additional donor–acceptor pairs and π-stacking structures, thereby broadening the absorption capacity across the UV–Vis-NIR spectrum through nonradiative transitions. The MPDA-8 coated Balsa wood and cellulose evaporator achieved high evaporation rates of 1.82 kg m−2 h−1 and 2.10 kg m−2 h−1, respectively, overcoming the limit of 2D interfacial evaporator. The small pores and fiber channels within the wood, coupled with the hydrophilicity of MPDA-8, facilitates efficient water transportation and reduces evaporation enthalpy. Outdoor evaporation experiments conducted under sunlight corroborated the practical viability of this material. This study introduces a new perspective for advancing synthetic melanins in photothermal applications through the nanoparticle pre-doping strategy.

The induced non-uniformity of magnetic field enables to enhance heat transfer through the annular gap in a uniform magnetic field three – five times

We have investigated the influence of the induced non-uniformity on thermomagnetic convection when the inner cylinder of an annular gap has high magnetic permeability and a special wave-like shape. The outer uniform magnetic field induces a non-uniformity, which causes thermomagnetic convection. The problem is analyzed numerically. The in-house code uses the finite volume method with exponential interpolation functions for vorticity and temperature and linear functions for the stream function and magnetic field potential. It was found that increasing the periodicity and amplitude of the wave-like structure enhances heat transfer by 30–50 % compared to a circular annular gap filled with magnetic fluid, and 3–5 times compared to an annular gap filled with ordinary fluid. Such a way of creating induced non-uniformity of magnetic field and convection enhancement is especially effective for microfluidics, as the gravitational Rayleigh number is low in this case, and it is a hard technical problem to create a non-uniform magnetic field in small channels by directly using permanent magnets.

Computer Design of the Regulating Working Element of the Channel Cleaning Equipment

Cleaning devices of channel systems used for irrigation of agricultural plants and mechatronic parts regulating their operations were analyzed, the issues of automation of construction design, measurement and management in this field were examined and the purpose of the work was determined. As the goal of the work, the issue of automation of the construction design, technological measurement and management process of the working body for efficient cleaning of small and medium-sized concrete-covered channels, bathtubs from sludge and weeds was set. A complex scheme of information, algorithmic and software support for the automation of the design, technological measurement and control of the mechatronic parts of the working body used for cleaning the channel and bathtub was proposed, and the issues of logical modeling and simulation of the drawing of 2- and 3-dimensional images of the working body were solved. Algorithms were developed using the production modeling method to automate the process of technological measurement, implementation and management, which accurately regulates the operations of the working body of the mechanical device of complex construction. In Solid Edge 2D, 3D software environments, the determination of the geometric shapes of the individual mechanical parts of the channel cleaning unit with a milling cutter, their sizes and types of materials is ensured, and the algorithm was developed using the logical modeling method. For the automation of the structural design process, the information security of the mechanical parts of the application object and the elements of the new design milling cutter device was created for the management of the database of drawings.

Construction of 2D zinc(II) MOFs with tricarboxylate and N-donor mixed ligands for multiresponsive luminescence sensors and CO2 adsorption.

The solvothermal reactions of ZnCl2·6H2O, benzene-1,3,5-tribenzoic acid (H3btb), and N-heterocyclic ancillary imidazole (Im) or aminopyrimidine (a mp) ligands led to the creation of two-dimensional (2D) zinc(II) based metal-organic frameworks (MOFs), (Me2NH2)2[Zn2(btb)2(Im)2]·2DMF·3MeOH (1) and (Me2NH2)2[Zn2(btb)2(amp)]·H2O·2DMF·MeOH (2). The btb3- ligands in 1 and 2 form an anionic 2D layered structure with a (63) honeycomb (hcb) topology by linking to Zn(II) centres through their carboxylate groups. The incorporation of N-heterocyclic auxiliary ligands Im and amp into the hcb nets resulted in the formation of a 2D hydrogen-bonded and covalently pillared bilayer structure featuring two-fold interpenetrating networks. Each of these networks consists of small channels that are occupied by Me2NH2 cations and solvent molecules. Both 1 and 2 emit blue luminescence emissions in the solid state at room temperature and exhibit a great selectivity and sensitivity for the detection of acetone and multiple heavy metal ions including Hg2+, Cu2+, Fe2+, Pb2+, Cr3+, and Fe3+ ions. At 1 bar, activated 1 and 2 demonstrate moderate capacities for adsorbing CO2 at room temperature, with a preference for CO2 over N2. Notably, at higher pressures (up to 20 bar), their activated samples 1 and 2 show a temperature-dependent enhancement of CO2 uptake while retaining good stability.

Thermal performance of a novel hybrid heat pipe with composite heat transfer characteristics

Considering the capillary threshold of oscillating heat pipes (OHP), a novel hybrid heat pipe (HHP) was designed with channels with hydraulic diameters that alternately exceed and fall below this threshold, parallelly arrayed within a unified copper substrate. This technology attains a comprehensive heat transfer performance within the HHP, seamlessly transitioning from pure phase change heat transfer to hybrid pulsating flow heat transfer to effectively accommodate the escalating demands of heat load. Performance and visualization are used to analyze the operational characteristics of HHP. The results indicate that the HHP mainly transfers heat through the phase change in the large channels in lower heat input, while the working fluid in the small channels remains calm. Once the heat input is sufficient, the geyser boiling in the large channels and the liquid slug pulsating in the small channels jointly carry out heat transfer. Furthermore, the liquid content in the large and small channels can be adaptively adjusted to each other. The high-speed liquid in the small channels can be squeezed into the large channels to ensure the sufficient pulsating space and achieve efficient heat transfer under high heat input. In addition, the operation of the HHP can be significantly impacted by the filling ratio (FR). In the phase change stage, the FR of 47.6 % can be considered as the turning point. After transitioning to the hybrid pulsating flow stage, the HHP with low FR can get a better performance. This new type of heat pipe with gradually changing operation characteristics may be critical to solve thermal problems in variable heat load domain.

Effects of initial soil moisture on rill erodibility and critical shear stress factors in the WEPP model across diverse soil types

Rill erosion, a significant issue in agricultural regions, is intricately linked to initial soil moisture conditions, affecting the development of concentrated flow erosion processes. However, understanding its dynamics amidst varying soil moisture conditions remain challenging. This study aimed to assess the impact of different soil moisture levels on rill erodibility parameters in the Water Erosion Prediction Project (WEPP) model and to evaluate soil cohesion across a spectrum of soils. Through laboratory experiments employing a small V-shaped rill channel, we investigated rill erodibility (Kr) and critical hydraulic shear stress (τcr), under three soil moisture scenarios: initially dry, saturated, and drainage, with incremental surface inflow rates. Additionally, we examined the efficiency of soil cohesion obtained from an Automated Soil Cohesion Measurement Apparatus in predicting Kr and τcr across various soil textures. Our analysis encompassed twenty soils representing nine texture classes, revealing significant correlations between basic soil properties, cohesion parameters, and WEPP model rill erodibility. Notably, initial soil moisture conditions exerted substantial influence on erodibility potentials. Soils with higher silt contents demonstrated better fits in terms of Nash-Sutcliffe model efficiency, particularly under initially dry and saturated conditions. However, predictions for initially drained soils yielded poor fits, emphasizing the intricate interplay between soil properties and hydrological conditions. In conclusion, our findings emphasize the critical role of topsoil water dynamics in rill erodibility. We propose that soil cohesion serves as a valuable predictor, complementing friction forces within the soil and enhancing simulations of rill erodibility under shallow flow conditions in rills, particularly in next-generation process-based modeling approaches.

Small Molecule APOL1 Channel Inhibitor Reduces Proteinuria, Rescues Podocyte Injury, and Reverses eGFR Decline in an APOL1-Mediated Kidney Disease Mouse Model

Small Molecule APOL1 Channel Inhibitor Reduces Proteinuria, Rescues Podocyte Injury, and Reverses eGFR Decline in an APOL1-Mediated Kidney Disease Mouse Model

Heat transfer augmentation by using different techniques in small scale channels: A review study

In this paper highlights the most significant recent developments in scientific study on Heat sinks are thermal management components made of materials with sufficient thermal conductivity qualities. Due to the increase in operating power and speed as well as the general reduction in system size, the issues of heat removal and temperature management have taken on increasing importance in these studies. Changing the geometry of extended surfaces, the material from which they were made, the working fluid that ran over them and or the dimension of the channel, are some of the subcategories in which studies have been conducted. The current review addresses the main recent findings in the forced convection heat transfer happened at laminar flow inside small scale diameters channels. The recent studies indicated a remarkable enhancement with the change of Re, D and internal geometry of channel. The configuration of flow passages also adopted as a different passive technique to enhance thermal fluid flow.

Response of submarine braided channels to varying inflow hydrographs: Geomorphic experiments and stratigraphic implications

AbstractSubmarine channels on the seafloor experience a range of turbidity current‐flood hydrographs. The characteristics of the flood hydrograph influence channel dimensions, the number of channel threads (i.e. braiding intensity) and the depositional properties of sandbars within the channels. However, the morphodynamic response of submarine braided channels to different hydrograph patterns is poorly understood. In this study, six geomorphic experiments are used to test how varied flood hydrographs affect the braiding intensity and sandbar geometry within submarine channels. Three experiments represent the control group with constant density‐current inflow, and three experiments use different time‐varying hydrograph patterns. The experiments show that, as the inflow‐to‐sediment discharge ratio increases, multiple small channels coalesce into a few main channels, causing a decrease in active braiding intensity defined by the channel threads with flow. When the flow returns to the initial low flow rate, active braiding intensity increases again. These observations show that the inflow‐to‐sediment discharge ratio determines the value of active braiding intensity. Additionally, active braiding intensity is directly proportional to dimensionless sediment‐stream power and dimensionless stream power, in agreement with previously established trends for both submarine and fluvial braided channels. In contrast to active braiding intensity changes, the measured sandbar aspect ratio and compactness ratio (i.e. ratio of planform area to perimeter) of submarine braided channels is insensitive to changes in the hydrograph. However, when inflows reach peak discharge, the higher transport capacity erodes pre‐existing deposits, forming noticeable erosional surfaces, and subsequently depositing thicker sandbars during that stage. These observations imply that sandbar planform morphology is largely insensitive to hydrograph, but hydrograph variability induces a greater variability in the resultant stratigraphic packages. The experimental results predict that field‐scale stratigraphy should be dominated by strata deposited during intervals of high flow, but that these strata will also exhibit reduced lateral continuity compared to formation scenarios with constant discharge.

Experimental void fraction measurement approach of small channel two-phase flow

This investigation presents a novel experimental approach for assessing void fraction parameters in two-phase flows within microchannels. The study critiques the conventional impedance methods that utilize alternating current (AC) for void fraction measurements, highlighting the inherent drawbacks such as ground capacitance interference and non-uniform current distribution. To circumvent these issues, the research introduces the use of direct current (DC), which ensures a homogeneous distribution across the conductor's cross-section, as a more reliable alternative. Termed the "Direct Impedance Method," this technique employs DC to enhance the accuracy of void fraction measurements. The study explores various geometric configurations of full-ring and half-ring electrodes, both vertical and horizontal, within a microchannel of 500 μm diameter. An empirical formula is derived to calculate the void fraction from the electrical data obtained. High-speed imaging at 4000 frames per second supplements the method by providing visual confirmation of the flow patterns. The comparative analysis of the direct impedance method and image processing using the homogeneous theoretical model reveals a deviation of approximately 2 %–10 % for the slug and annular flow pattern. In contrast, the deviation is more for the bubble pattern. The results affirm that the Direct Impedance Method is a cost-effective and reasonably precise technique for small-channel applications. Its accuracy is inversely proportional to the channel diameter, rendering it unsuitable for channels larger than 2 mm. The method's low construction cost further enhances its practical appeal.

Influence of flood events on the response of steep and coarse-grained channels to base-level lowering in an arid setting

The Dead Sea level has been undergoing a continuous and rapid lowering, presently ∼ 1.1 m/yr, providing a real time laboratory to examine the response of drainage systems to base level drop. There is a gap of knowledge concerning the impact of floods on the fluvial system in an environment of continuous base level lowering. Such knowledge is of pronounced importance due to the world-wide reduction of natural water recourses caused by human and climate impacts. We relate the effects of flash floods on morphological changes in small, steep and coarse-grained alluvial channels as a response to a rapid base level fall. We studied the steep (7–9 %) David and Qedem channels draining to the Dead Sea by (i) monitoring flow events using depth transducers and (ii) topographic changes by repeat drone-based photogrammetric surveys to quantify fluvio-morphological dynamics, and (iii) analyzed boulder-related bedforms and their distance from the thalweg. Altogether 15 monitored flow events of varying magnitude led to a wide range of fluvio-morphological changes. Considerable erosion occurred as expressed by bank collapse and channel bed incision. Small events displayed incision with morphological changes limited to the downstream reach, while larger events caused morphological changes throughout the entire channel. Substantial deposition at the outlet occurred together with local mechanisms of deposition upstream. The extents of erosion and net volumes of change highly correlated with event peak-discharge and event water volume. Frequent thalweg deflections occurred, some of which were related to the interaction with boulders. Boulder ribs displayed processes of formation/destruction in multiple phases, often occurring in larger events. The examined aspects illustrate the unique dynamics of a continuously unstable fluvial system under a flash-flood hydrological regime and its impact on fan delta incision and sediment transport processes.

Why do phyto- and zooplankton exhibit different patterns of seasonal dynamics in the large Ob river-floodplain system (West Siberia)?

AbstractA floodplain is considered as the basis for high production and biodiversity of large rivers. To test the hypothesis of the determining role of the floodplain as a supplier of plankton to the channel of a large unregulated river, we implemented a three-year study in the Ob river-floodplain (West Siberia, Russia) and revealed that factors of seasonal dynamics and sources of phyto- and zooplankton supply to the channel differed. The riverine phytoplankton was formed mostly in the main river and small side channels. The driving factor of its seasonal dynamics in the main channel and the permanently connected floodplain was water temperature, whereas in mostly isolated floodplain lakes—it was the availability of nutrients. Zooplankton in the channel was largely formed due to “recruits” arrival from the floodplain reaches. Its abundance in the channel with connection to the river-floodplain areas depended on temperature and phytoplankton amount. This study casts a light upon some major factors of seasonal dynamics of phyto- and zooplankton in the river-floodplain systems of large lowland rivers and serves the basis for the development of the flood pulse concept and monitoring program for rivers with a long freeze-up period.