Purpose: MR Enterography (MRE) aids assessment of Crohn's disease (CD) but may also be indicated in the investigation of other SB pathology. We studied the frequency and clinical impact of incidental findings detected by MRE in patients with suspected or known CD. Methods: We conducted a retrospective review of 1022 MRE studies performed between June, 2009 and February, 2013 at our institution. Clinical data (demographics, disease characteristics and therapy) were obtained from electronic patient records. Incidental findings were defined as unexpected lesions in or outside the small intestine, unknown at the time of referral and unrelated to inflammatory bowel disease (IBD). Results: Of 1,022 MRE studies 500 patients had a diagnosis of IBD, 418 had CD, 61 had ulcerative colitis (UC) and 21 had IBD unclassified (IBDU). Of 418 CD patients, 243 were female, mean age 36. Abnormalities were noted in 306 MRE scans, 170 active non-stricturing, 121 active stricturing and 13-fibrostenotic disease. Within active groups were 35 fistulae and 12 abscesses. Incidental findings included colonic inflammation (10), gallstones (17), ovarian cysts (22), jejunal intussusception (1), sacroileitis (1), renal cysts (11), hepatic cysts (12), splenic haemangioma (1), mesenteric abscess (1), adrenal nodule (2), uterine fibroid (5), chronic pancreatitis (1) and splenomegaly (2). Eighty-two studies were performed in UC or IBDU; 48 were female, mean age 33. Seventeen patients had small bowel thickening with signs of active inflammation in 12/17. Incidental findings included a right ischio-anal fossa collection, pancreatic divisum, gallstones, liver and ovarian cysts, diverticular disease, large bowel abnormalities in 6 patients, colitis (5) and colonic polyps (1). MRE was performed in 522 patients without IBD. Indications included iron deficiency anaemia, abdominal pain, weight loss, diarrhoea, rectal bleeding, vomiting and abnormal colonoscopy. Findings included small bowel thickening (4), sub-acute small bowel obstruction (2), small bowel stricture (1), small bowel malignancies (2) and small bowel intussusception (1). Incidental findings included ovarian, hepatic and renal cysts, adrenal adenoma, splenic and liver haemangioma, PUJ obstruction, AAA, liver metastases, gallstones, pelvic abscess, uterine fibroids, large bowel stricture, diverticular disease, cirrhosis, lymphadenopathy, horseshoe kidney, atrophic pancreas and acute appendicitis. Conclusion: A small but significant proportion of patients have important incidental findings at MRE. MRE can add meaningfully to the investigation of SB pathology. A careful selection of patients can be achieved through a collaborative multi-disciplinary approach.