The emergence of new digital technologies and the existence of digital media has had an important impact in changing the operation of business environment. Correspondingly, the diversity of applications and digital media has now provided a broader space for the users, including the entrepreneurs, to enhance and upsurge their contact with customers and suppliers in entrepreneurship sector. Information and Communication Technology (ICT) and the Web are particularly the integrated and dynamic tool in nurturing entrepreneurship as well as act as the communication and marketing tool to grow the business. It is important to explore the new phenomenon in entrepreneurship that is closely related to ICT usage. The purpose of this study was to identify the patterns of ICT usage and to analyze the relationship between digital inclusion and its implications among entrepreneurs of small and medium enterprises (SMEs). The quantitative method is employed in this study with samples aimed at focusing on entrepreneurs in the Klang Valley. A questionnaire was distributed directly to 500 respondents aged between 18 to 55 years old. The data collected were analyzed descriptively and with correlation inference by using the SPSS software. The finding indicated a significant and strong relationship between digital inclusion and its implications (p <0.005, r = .685) among entrepreneurs of SMEs. It revealed that the entrepreneurs with high involvement in ICT usage have high implications in terms of innovation and business satisfaction. The study recommends that the government should play a dynamic role in education and training for the development of the SMEs as well as bridge the gap among the SMEs to adopt the use of digital media tools. In sum, the use of ICT contributes to enhance a number of benefits such as to be more competitive, innovative, expanding business networks and gaining more global marketing opportunities.