Slow Inflation Research Articles

Cuff inflation time significantly affects blood flow recorded with venous occlusion plethysmography

PurposeWe tested whether the values of limb blood flow calculated with strain-gauge venous occlusion plethysmography (VOP) differ when venous occlusion is achieved by automated, or manual inflation, so providing rapid and slower inflation, respectively.MethodIn 9 subjects (20–30 years), we calculated forearm blood flows (FBF) values at rest and following isometric handgrip at 70% maximum voluntary contraction (MVC) when rapid, or slower inflation was used.ResultRapid and slower cuff inflation took 0.23 ± 0.01 (mean ± SEM) and 0.92 ± 0.02 s, respectively, reflecting the range reported in published studies. At rest, FBF calculated from the 1st cardiac cycle after rapid and slower inflation gave similar values: 10.5 ± 1.4 vs. 9.6 ± 1.3 ml dl− 1 min− 1, respectively (P > 0.05). However, immediately post-contraction, FBF was ~ 40% lower with slower inflation: 54.6 ± 5.1 vs. 33.8 ± 4.2 ml dl− 1 min− 1 (P < 0.01). The latter value was similar to that calculated over the 3rd cardiac cycle following rapid inflation: 2nd cardiac cycle: 40.5 ± 4.5; 3rd cycle: 32.6 ± 4.5 ml dl− 1 min− 1. Regression analyses of FBFs recorded at intervals post-contraction showed those calculated over the 1st, 2nd, or 3rd cardiac cycles with rapid inflation correlated well with those from the 1st cardiac cycle with manual inflation (r = 0.79, 0.82, 0.79; P < 0.01). However, only the slope for the 3rd cycle with rapid inflation vs. slower inflation was close to unity (2.07, 1.34, and 0.94, respectively).ConclusionThese findings confirm that the 1st cardiac cycle following venous occlusion should be used when calculating FBF using VOP and, but importantly, indicate that cuff inflation should be almost instantaneous; just ≥ 0.9 s leads to substantial underestimation, especially at high flows.

A pilot study of venous flow augmentation using a novel mechanical graded intermittent sequential compression device for venous insufficiency

BackgroundGuidelines as well as multiple RTCs support the use of intermittent pneumatic compression (IPC) for the treatment of venous leg ulcers when conservative measures fail. Unfortunately, the clinical usefulness of IPC is significantly limited by the physical limitations of pneumatic motors, which leads to bulky devices with slow inflation cycles, uncomfortable sleeves, lack of patient mobility, and ultimately poor patient compliance with therapy. A novel mechanical device for lower leg graded intermittent sequential compression was designed to address these limitations of IPC therapy for venous leg ulcer treatment by providing rapid compression cycles in a truly wearable device that offers the additional benefit of monitoring compression dose and patient compliance. The wearable intermittent compression (WIC) device was hypothesized to provide improved augmentation of venous flow compared with both baseline and standard IPC therapy. MethodsTen patients with Clinical, Etiologic, Anatomic and Pathophysiologic class 3 to 6 venous insufficiency were recruited under institutional review board approval. The primary end point for the study was augmentation of venous blood flow as measured by peak venous velocity. Patients underwent measurement of peak venous velocity in centimeters per second at the popliteal and femoral veins for the following conditions: (1) baseline, (2) WIC device on a low setting, and (3) WIC device on a high setting. In five patients, an additional measurement of peak venous velocity in centimeters per second at the popliteal and femoral veins was completed while wearing a commercially available IPC device. ResultsBoth low and high settings of the WIC device resulted in higher average peak venous velocities when compared with both baseline and the IPC device (P < .05). No patients reported discomfort with either the WIC device or the IPC device during therapy. ConclusionsThe WIC device significantly increases the augmentation of venous flow as measured by peak venous velocity in both the popliteal and femoral veins in patients with Clinical, Etiologic, Anatomic and Pathophysiologic class 3 to 6 venous insufficiency. In addition, the WIC device was found to be easy to use and comfortable during therapy. Future studies are planned to determine if the WIC improvements in venous flow augmentation and patient compliance will lead to higher rates of venous ulcer healing.

Lamellar projections in the endolymphatic sac act as a relief valve to regulate inner ear pressure.

The inner ear is a fluid-filled closed-epithelial structure whose function requires maintenance of an internal hydrostatic pressure and fluid composition. The endolymphatic sac (ES) is a dead-end epithelial tube connected to the inner ear whose function is unclear. ES defects can cause distended ear tissue, a pathology often seen in hearing and balance disorders. Using live imaging of zebrafish larvae, we reveal that the ES undergoes cycles of slow pressure-driven inflation followed by rapid deflation. Absence of these cycles in lmx1bb mutants leads to distended ear tissue. Using serial-section electron microscopy and adaptive optics lattice light-sheet microscopy, we find a pressure relief valve in the ES comprised of partially separated apical junctions and dynamic overlapping basal lamellae that separate under pressure to release fluid. We propose that this lmx1-dependent pressure relief valve is required to maintain fluid homeostasis in the inner ear and other fluid-filled cavities.

Is There a Productivity Puzzle in the OECD Economies?&amp;lt;sup&amp;gt;1&amp;lt;/sup&amp;gt; Or Why Has Economic Recovery Since the Great Financial Crisis Not Produced Increased Inflation?

This paper investigates whether there has been a structural shift in inflation since a recovery began in the OECD economies. For policy purposes, it is important to be sure that such shifts are significant statistically, are likely to be sustained over the near future and be evenly distributed over the member economies so that no one of them is damaged by anti-inflation measures taken to help others. We approach the problem in two steps: first we examine the circumstantial and informal evidence, and then conduct formal statistical tests for structural changes in euro area inflation in 2015-2016. We find no evidence of a structural change. An even distribution of inflation criterion is the closest to being satisfied, but the other two are far from satisfied in any formal sense. The question remains: why has there been no inflation in the recovery since 2014? To answer that question, we demonstrate how low growth in real wages and self-reinforcing low productivity growth produces slow output growth and low inflation; and how low real wages and productivity in turn lead to low investment. This model fits the data well, down to the lack of labour and total factor productivity, and to the substitution of cheaper labour for excess capital stock. It implies a fall in investment spending (also seen in the data) that extends the period for which the low productivity-low inflation outcomes apply.

Inflation in Modern Russia: Theoretical Foundations, Specific Features of Manifestation and Regional Dimension

The purpose of the article is to characterize the development and specific features of inflation in Russia on the basis of its theoretical justification and practical analysis. The article discusses the monetarist and Keynesian approaches to the characterization of inflation. The paper shows that the equation of exchange from the quantity theory of money, which is the basis of the monetarist theory of inflation, does not allow to make an unambiguous conclusion about the direct relationship between money supply and price level in the economy. The authors give the theoretical substantiation of cost-push inflation from the position of microeconomic theory, which is denied by the representatives of the monetarist school. We characterize the specific features of inflation in the period of market transformations in Russia. The article shows the considerable role of the cost factors of cost-push inflation: the monopolization of the economy, rise in the prices of energy and raw materials. There is an absence of the direct relationship between inflation and money supply growth in large part of the period of the 2000. The authors determine the dependence between the exchange rate and inflation in the Russian economy, which is most evident during periods of significant devaluation of the national currency, as a rule, associated with a significant increase in world oil prices. The paper notes that the significant decline in aggregate demand that occurred in Russia in recent years have reduced the level of inflation in 2016. Despite this, the reduction of inflation and its transformation to slow cost-push inflation was combined with negative consequences for the economy: the decrease of investments and production development, reduction of the living standards of the population. The authors conducted the analysis of inflation on the level of the subjects of the Russian Federation, which has confirmed the significant role of causes of cost-push inflation in the economy. The research has led to the conclusion about the appropriateness of measures on the stimulation of aggregate demand and the development of the national economy by reducing interest rates, increasing investment activity, developing competition and efficiency of antitrust regulation.

Transcatheter aortic valve implantation with a Sapien 3 Commander 20 mm valves in patients with degenerated 19 mm bioprosthetic aortic valve.

Transcatheter aortic valve implantation (TAVI) in patients with degenerated bioprosthetic aortic valve has been successfully performed as an alternative to surgery. We describe our initial experience of valve-in-valve TAVI in five patients, using new generation Edwards Sapien 3 transcatheter heart valves implanted into degenerated 19 mm bioprosthetic valves. 20-mm Edwards S3 valves were offered for compassionate use. All patients had significant aortic valve stenosis. The main vascular access was achieved and pre-closed with two Proglide closure devices in one patient and Prostar closure devices in four patients. For each TAVI procedure an Edwards 14 French sheath was inserted without complication and sutured in place. The Sapien 3 Commander delivery system was inserted and the valve was aligned in the descending aorta. The 20-mm Sapien 3 valve was deployed with slow continuous inflation during rapid right ventricular pacing. The cranial edge of the Edwards S3 valve was aligned with the cranial radiopaque markers of bioprosthesis to minimize paravalvular leak. Post-deployment angiography, transesophageal echocardiography and aortogram confirmed absence of mild aortic insufficiency and no increase in trans-aortic gradient when compared to a naïve 19 mm bioprosthetic valve. Valve-in-valve TAVI with the Edwards S3 transcatheter heart valve for degenerative bioprosthetic aortic valves is technically feasible. The proper position of the stented valve minimizes the risk for post-procedure paravalvular insufficiency and provides good transaortic pressure gradient. © 2016 Wiley Periodicals, Inc.

SUSY see-saw and NMSO(10)GUT inflation after BICEP2

Supersymmetric see-saw slow roll inflection point inflation occurs along a MSSM D-flat direction associated with gauge invariant combination of Higgs, slepton and right-handed sneutrino at a scale set by the right-handed neutrino mass $M_{{\nu }^{c}} \sim 10^{6}\!\,-\,\!10^{13}$ GeV. The tensor to scalar perturbation ratio r∼10−3 can be achieved in this scenario. However, this scenario faced difficulty in being embedded in the realistic new minimal supersymmetric SO(10) grand unified theory (NMSO(10)GUT). The recent discovery of B-mode polarization by BICEP2, changes the prospects of NMSO(10)GUT inflation. Inflection point models become strongly disfavoured, as the trilinear coupling of SUSY see-saw inflation potential gets suppressed relative to the mass parameter favoured by BICEP2. Large values of r≈0.2 can be achieved with super-Planck scale inflaton values and mass scales of inflaton ≥10 13 GeV. In NMSO(10)GUT, this can be made possible with an admixture of heavy Higgs doublet fields, i.e., other than MSSM Higgs field, which are present and have masses of order GUT scale.

Abstract 19521: Slow and Prolonged Inflations of Percutaneous Transluminal Angioplasty is as Effective as Stenting in Peripheral Vascular Interventions

Background: The benefit of stent implantation over percutaneous transluminal angioplasty (PTA) in patients undergoing peripheral vascular interventions (PVI) has not been well described. Original data supporting stents over PTA was in an era without routine atherectomy, and more recent data including chronic total occlusions (CTO) and longer lengths demonstrated no difference. Method: 551 patients undergoing PVI were identified from January 2011 to January 2015. Success was defined by a composite improvement of ankle brachial index (ABI) to over 0.9, an ultrasound velocity of less than 250 m/s, or Rutherford classification improvement. All PTA was performed over a slow inflation over 5 minutes. A Pearson chi-square and multivariate analyses were used to determine results. Results: 274 (49.72%) patients received PTA alone and 277 (50.28%) received stents. Although more patients with diabetes and longer lesion length were in the PTA group, stenting did not improve the individual or composite success endpoints. Even when correcting for these differences in a multivariate analysis. Conclusion: PTA is as effective as stenting even in patients with diabetes and long lesion lengths (over 100mm). More data is necessary as drug eluting balloon angioplasty has been shown to improve patency over PTA, however the more slow and prolonged inflations in PTA may be responsible for these findings.

Temperature in warm inflation in non-minimal kinetic coupling model

Warm inflation in the non minimal derivative coupling model with a general dissipation coefficient is considered. We investigate conditions for the existence of the slow roll approximation and study cosmological perturbations. The spectral index, and the power spectrum are calculated and the temperature of the universe at the end of the slow roll warm inflation is obtained.

Early universe cosmology, effective supergravity, and invariants of algebraic forms

The presence of light scalars can have profound effects on early universe cosmology, influencing its thermal history as well as paradigms like inflation and baryogenesis. Effective supergravity provides a framework to make quantifiable, model-independent studies of these effects. The Riemanian curvature of the Kahler manifold spanned by scalars belonging to chiral superfields, evaluated along supersymmetry breaking directions, provides an order parameter (in the sense that it must necessarily take certain values) for phenomena as diverse as slow roll modular inflation, non-thermal cosmological histories, and the viability of Affleck-Dine baryogenesis. Within certain classes of UV completions, the order parameter for theories with $n$ scalar moduli is conjectured to be related to invariants of $n$-ary cubic forms (for example, for models with three moduli, the order parameter is given by the ring of invariants spanned by the Aronhold invariants). Within these completions, and under the caveats spelled out, this may provide an avenue to obtain necessary conditions for the above phenomena that are in principle calculable given nothing but the intersection numbers of a Calabi-Yau compactification geometry. As an additional result, abstract relations between holomorphic sectional and bisectional curvatures are utilized to constrain Affleck-Dine baryogenesis on a wide class of Kahler geometries.

Inflation from cosmological constant and nonminimally coupled scalar

We consider inflation in a universe with a positive cosmological constant and a nonminimally coupled scalar field, in which the field couples both quadratically and quartically to the Ricci scalar. When considered in the Einstein frame and when the nonminimal couplings are negative, the field starts in slow roll and inflation ends with an asymptotic value of the principal slow roll parameter, $\epsilon_E=4/3$. Graceful exit can be achieved by suitably (tightly) coupling the scalar field to matter, such that at late time the total energy density reaches the scaling of matter, $\epsilon_E=\epsilon_m$. Quite generically the model produces a red spectrum of scalar cosmological perturbations and a small amount of gravitational radiation. With a suitable choice of the nonminimal couplings, the spectral slope can be as large as $n_s\simeq 0.955$, which is about one standard deviation away from the central value measured by the Planck satellite. The model can be ruled out by future measurements if any of the following is observed: (a) the spectral index of scalar perturbations is $n_s>0.960$; (b) the amplitude of tensor perturbations is above about $r\sim 10^{-2}$; (c) the running of the spectral index of scalar perturbations is positive.

Earthquake triggered rock falls and their role in the development of a rock slope: The case of Skolis Mountain, Greece

Inventory of pre-earthquake and earthquake triggered landslides is used to provide insight into the interplay between climatic and tectonic forcing in the development of the rock slopes of the Skolis Mountain, in the NW Peloponnese. Aerial photograph analysis and surface mapping indicate that the Skolis Mountain is characterized by long-term climatically and tectonically controlled rock falls forming taluses. Temporally these taluses show a slow progressive inflation in surface area from 1945 to 2007. However, the post-earthquake surface area of the rock falls increased three times. Similarly 75 rock fall sites before the earthquake, increased into 89 after the Movri Mountain earthquake (Mw 6.4). In addition, during the earthquake a series of isolated rock falls descended Skolis slopes causing threat of the Santomerion village and blocking significant part of the dirt roads around it. These boulders are clustered in three areas beyond the base of taluses. The rock slope failures are controlled by a complex array of discontinuities that are conveniently related to rock mass classification following the geological strength index. These discontinuities are associated with joints and faults caused during the formation of the Hellenides fold- and thrust-belt, and/or related tectonic damage. We infer that a dense pattern of fractures in limestone plays a crucial role in the reactivation of movement within the rock falls during the 2008 Movri Mountain earthquake. All these data are used to define two borders, the taluses base and the rock fall hazard border beyond the base of taluses. For defining these borders we use the angle β drawn from the boulders' release zone down its maximal runout points. Our results indicate that the border defined by the β=33° corresponds to the climatically driven rock falls while the β=24° border is defined as the boulders' maximum runout during earthquakes.

Leading slow roll corrections to the volume of the universe and the entropy bound

We make an extension to recent calculations of the probability density \rho(V) for the volume of the universe after inflation. Previous results have been accurate to leading order in the slow roll parameters \epsilon=\dot{H}/H^2 and \eta=\ddot{\phi}/(\dot{\phi} H), and 1/N_c, where H is the Hubble parameter and N_c is the classical number of e-foldings. Here, we present a modification which captures effects of order \epsilon N_c, which amounts to letting the parameters of inflation H and \dot{\phi} depend on the value of the inflaton \phi. The phase of slow roll eternal inflation can be defined as when the probability to have an infinite volume is greater than zero. Using this definition, we study the Laplace transform of \rho(V) numerically to determine the condition that triggers the transition to eternal inflation. We also study the average volume <V> analytically and show that it satisfies the universal volume bound. This bound states that, in any realization of inflation which ends with a finite volume, an initial volume must grow by less than a factor of exp(S_{dS}/2), where S_{dS} is the de Sitter (dS) entropy.

Dynamic clinical measurements of voluntary vaginal contractions and autonomic vaginal reflexes.

The vaginal canal is an active and responsive canal. It has pressure variations along its length and shows reflex activity. At present, the prevailing idea is that the vaginal canal does not have a sphincter mechanism. It is hypothesized that an active vaginal muscular mechanism exists and might be involved in the pathophysiology of genito-pelvic pain/penetration disorder. The aim of this study was to detect the presence of a canalicular vaginal "sphincter mechanism" by measuring intravaginal pressure at different levels of the vaginal canal during voluntary pelvic floor contractions and during induced reflexive contractions. Sixteen nulliparous women, without sexual dysfunction and pelvic floor trauma, were included in the study. High-resolution solid-state circumferential catheters were used to measure intravaginal pressures and vaginal contractions at different levels in the vaginal canal. Voluntary intravaginal pressure measurements were performed in the left lateral recumbent position only, while reflexive intravaginal pressure measurements during slow inflation of a vaginal balloon were performed in the left lateral recumbent position and in the sitting position. Intravaginal pressures and vaginal contractions were the main outcome measures. In addition, a general demographic and medical history questionnaire was administered to gain insight into the characteristics of the study population. Fifteen out of the sixteen women had deep and superficial vaginal high-pressure zones. In one woman, no superficial high-pressure zone was found. The basal and maximum pressures, as well as the duration of the autonomic reflexive contractions significantly exceeded the pressures and the duration of the voluntary contractions. There were no significant differences between the reflexive measurements obtained in the left lateral recumbent and the sitting position. The two high-pressure zones found in this study, as a result of voluntary contractions and, even more pronounced, as a result of reflexive contractions on intravaginal stimulation, support the hypothesis that the vaginal canal has an active and passive canalicular sphincter mechanism. Further investigation of this sphincter mechanism is required to identify its role in the sexual response and genito-pelvic pain/penetration disorder.

Derivation of recruitment function from the pressure–volume curve in an acute lung injury model

Lung volume changes involve the recruitment of collapsed alveoli and the expansion of already opened alveoli. This study aimed to determine the alveolar recruitment function by using a mathematical model from a pressure–volume curve (P–V curve). We assumed a lung model as VL=R(P)V0f(P), where R recruitment function is the fraction of recruited alveoli, V0 is the resting lung volume at FRC of a fully recruited lung, and f(P) corresponds to the normalized compliance function of the lungs open to ventilation. Seven white rabbits were subjected to saline-lavage lung injury, and P–V curves were calculated using the slow inflation technique. We obtained the P–R curve from the P–V curve, and two curves were differently shaped after lung injury. We concluded that the recruitment function was obtained from the P–V curve and that the P–R curve estimated the recruitment and derecruitment status.

Prices and Wages

Inflationary pressures cooled over the latter months of 2013, with CPI inflation finally moving back to the 2% target for the first time in four years in December. The slowdown in inflation was largely a function of base effects; big rises in food prices in the autumn of 2012 were not repeated last year and increases in domestic energy bills, while still very large, were also lower than in the previous year. In addition, the impact of higher university tuition fees was smaller in 2013 than in 2012, which also helped to slow inflation a little…

Experimental model to evaluate the effect of hydrothorax and lobar resection on lung compliance†

The objective of this study was to evaluate to what extent lung compliance is affected by the individual and combined action of lung resection and hydrothorax in an animal model. Anaesthetized and mechanically ventilated rabbits (weight range 2 ÷ 2.2 kg) were randomized in two groups: (i) experimental hydrothorax (from 2 to 8 ml) (n = 5) and (ii) right lower lobe lobectomy (n = 4) and right middle plus lower lobe resection (n = 2). To obtain lung compliance, we measured alveolar, oesophageal pressures and lung volume during slow inflation manoeuvres in control conditions and after hydrothorax or lung resection. Lung compliance was estimated as the change in lung volume divided by the change in transpulmonary pressure. Based on the changes in compliance of the whole lung, we calculated the corresponding changes in compliance of the right lung, which was directly exposed to unilateral hydrothorax and lobectomy. Average total lung compliance in the control was 3.3 ± 0.8 (SD) ml/cmH2O. Eight millilitres of hydrothorax significantly decreased (P < 0.001) lung compliance to 2.7 ± 0.7 ml/cmH2O and increased pleural liquid pressure at the bottom of the cavity from -1 cmH2O up to ∼ 2.5-3 cmH2O. Resection of the right lower lobe significantly decreased (P < 0.001) lung compliance to 1.75 ± 0.3 ml/cmH2O. Resection of the right middle plus lower lobes significantly decreased (P < 0.001) lung compliance to 1.52 ± 0.4 ml/cmH2O. Following hydrothorax, the decrease in right lung compliance (∼ 45%) was much greater than that expected based on the estimated decrease in right lung volume (20%). We attribute this difference to the fact that hydrothorax causes the lung to be exposed to positive, rather than sub-atmospheric, pressure, causing atelectasis. Following lobectomy, right lung compliance decreased by 62 and 80% for estimated decreases in lung volume of 30 and 60%. This difference could reflect inaccuracy in the estimate of lung volume reduction based on resected weight and/or surgical damage. We conclude that potential detrimental effects of hydrothorax and lobar resection decrease lung compliance and expose the lung to the risk of over-distension when a chest drain is applied.

Attractor behaviour in ELKO cosmology

We study the dynamics of ELKO in the context of accelerated phase of our universe. To avoid the fine tuning problem associated with the initialconditions, it is required that the dynamical equations lead to an early-time attractor. In the earlier works, it was shown that the dynamical equations containing ELKO fields do not lead to early-time stable fixed points. In this work, using redefinition of variables, we show that ELKO cosmology admits early-time stable fixed points. More interestingly, we show that ELKO cosmology admit two sets of attractor points corresponding to slow and fast-roll inflation. The fast-roll inflation attractor point is unique for ELKO as it is independent of the form of the potential. We also discuss the plausible choice of interaction terms in these two sets of attractor points and constraints on the coupling constant.

STRUCTURAL CHANNELS FOR UKRAINIAN LABOUR MIGRATION IN THE CZECH REPUBLIC

1. Introduction In the 2000s and the 2010s, migration to the CEE countries (Central and East European countries) gained a special significance. There exists an observable pattern of East-West migration, on the one hand from New Member States (NMS) of the EU to Western Europe, on the other hand from Newly Independent Countries (NIS) to NMS of the EU. Leon-Ledesma, Piracha (2001) characterized the migration from CEE as temporary and short-term. The Czech Republic is, due to its advantageous geographical location in the heart of Europe, a very important country for European migrants--either as a final destination or a transitive point. From all post-Communist countries in Central and Eastern Europe, the Czech Republic receives the largest part of foreign labour force, with Ukrainian workers as a most important group (Figure 1). In 2009 Ukrainians comprised 21% of all immigrants and in 2006 their share was even larger--over 30 thousands of immigrants from Ukraine constituted 46% of overall immigration (CZSO 2011). Generally immigrants from non-EU countries comprise 68% of all foreigners in the Czech Republic, from which 43% are originally from Ukraine. The process of transformation in Ukraine that followed the collapse of the Soviet Union is still on-going and the country faces high unemployment, corruption, slow economic development and high inflation. The economic development of the country is slowed down by political environment and situation of dependency on Russian energy sources and struggles for power. The discontent with the situation in the country reached the point where people started the socalled Orange revolution as a response to 2004 parliament election (see e.g. Chaban and Vernygora 2010). However, pro-Western policy of the new government was not successful and new elections brought pro-Russian forces back to power (Wilson 2005, Strielkowski and Glazar 2012). The collapse of the Soviet Union triggered migration movement from Ukraine to the West (Malynovska 2008, Duvell 2006). There was also change in the type of migration--people did not migrate due to the ethical and political reasons, but mainly due to the economic ones (see e.g. Mendes 2009, or Jelinkova et al. 2011). Ukraine became an essential supply of labour for member states of the EU since more than half of migrants enter EU's labour markets (Siar 2008, Malynovska 2008, or Mendes 2009). Ukrainian migration is typically circular (i.e. with intention to return back regularly or for good), 80% of emigrants long to come back to Ukraine eventually, they maintain relationships with families, stay in direct contact, quite often are able to come home and they also realize investments in Ukraine (Markov et al. 2009). [FIGURE 1 OMITTED] Currently more than 10% of Ukrainian population (1/5 of working age population) work abroad, typically on temporary basis (Duvell 2006). According to Siar (2008) 15.7% of households have at least one or more members with experience of working abroad. Most often Ukrainians are engaged in secondary labour market and usually they do not constitute competitive counterparts to local workers (Markov et al. 2009). They are usually working in the building and construction sector, in housekeeping and agricultural industry (Vollmer et al. 2010). For the whole decade the GDP growth was negative and economy started to recover at the beginning of the new century. That did not automatically mean that the recovery completely helped the soundness of economy. The GDP of the country in 2006 resulted in 63% and in 2007 in 68% of the level in 1989. The world economic crisis caused further shock for the economy when in 2009 GDP shrank by 15% (Kowalski and Polowczyk 2012). The evolvement of GDP per capita in Ukraine and in the Czech Republic is depicted in Figure 2. The striking difference between values of GDP per capita is one of the evidence of better standards of living in the Czech Republic and thus these values can be understood as an important motivation for Ukrainian migrant workers at the time of their choice of destination country. …

Supersymmetric seesaw inflation

Supersymmetric Unified theories which incorporate a renormalizable Type I seesaw mechanism for small neutrino masses can also provide slow roll inflection point inflation along a flat direction associated with a gauge invariant combination of the Higgs, slepton and right handed sneutrino superfields. Inflationary parameters are related to the Majorana and Dirac couplings responsible for neutrino masses with the scale of inflation set by a right-handed neutrino mass $M_{\nu^c} \sim 10^6-10^{12}$ GeV. Tuning of the neutrino Dirac and Majorana superpotential couplings and soft Susy breaking parameters is required to enforce flatness of the inflationary potential. In contrast to previous inflection point inflation models the cubic term is dominantly derived from superpotential couplings rather than soft A-terms. Thus since $M_{\nu^c}>>M_{Susy}$ the tuning condition is almost independent of the soft supersymmetry breaking parameters and therefore more stable. The required fine tuning is also less stringent than for Minimal SUSY Standard Model (MSSM) inflation or Dirac neutrino 'A-term" inflation scenarios due to the much larger value of the inflaton mass. Reheating proceeds via `instant preheating' which rapidly dumps all the inflaton energy into a MSSM mode radiation bath giving a high reheat temperature $T_{rh} \approx M_{\nu^c}^{3/4}\, 10^{6}$ GeV $\sim 10^{11}- 10^{15} $ GeV. Thus our scenario requires large gravitino mass $> 50 $ TeV to avoid a gravitino problem. The `instant preheating' and Higgs component of the inflaton also imply a `non-thermal' contribution to Leptogenesis due to facilitated production of right handed neutrinos during inflaton decay. We derive the tuning conditions for the scenario to work in the realistic New Minimal Supersymmetric SO(10) GUT and show that they can be satisfied by realistic fits.