Sleep Quality In Hemodialysis Patients Research Articles

The effect of the massage on cramp frequency, cramp severity, and sleep quality of hemodialysis patients: A randomized controlled trial.

Leg muscle cramps and compromised sleep patterns are prevalent issues experienced by individuals undergoing hemodialysis treatment. The aim of this study was to assess the impact of massage therapy on hemodialysis patients experiencing cramping, specifically focusing on the frequency and severity of cramps, as well as the quality of sleep. This research involved 36 hemodialysis patients. The intervention group received intradialytic massage targeting the lower extremities, administered three times a week for a total of six sessions over a 2-week period. Data collection utilized a Patient Information Form, the Pittsburgh Sleep Quality Index, the Visual Analog Scale, and a Patient Follow-Up Form. The study revealed a significant reduction in both the frequency and severity of cramps experienced by patients in the intervention group during hemodialysis sessions and at home, from the end of one session to the beginning of the next, compared to the control group (p < 0.05). This effect was observed over the course of six dialysis sessions. Additionally, there was a notable decrease in the mean total score of the Pittsburgh Sleep Quality Index (PSQI) among participants in the intervention group, declining from 9.00 ± 3.79 prior to massage therapy to 5.94 ± 2.84 post-massage (p < 0.001). Conversely, no significant change was observed in the control group, highlighting a notable disparity between the intervention and control groups in terms of sleep quality improvement. The investigation revealed that employing intradialytic massage on the lower extremities led to a reduction in both the frequency and severity of cramps, while also eliciting a positive impact on the sleep quality of patients undergoing hemodialysis.

The impact of photobiomodulation on sleep and life quality in hemodialysis patients: A randomized controlled trial.

The quality of life (QoL) and sleep quality are closely linked to the physical and psychological health of end-stage renal disease (ESRD) patients, especially those underwent hemodialysis (HD) therapy. This study aims to investigate the impact of 830nm laser treatment on improving QoL and sleep quality in HD patients. Forty ESRD patients participated in this study. 830nm laser was used to radiate on the palm (at dose of 256.10J/cm2), ST 36 and KI 1 acupoints (at dose of 109.76J/cm2) of HD patients, and QoL and sleep quality questionnaires were utilized to assess changes following the treatment. After 830nm laser radiation, lower global Pittsburgh Sleep Quality Index and Athens Insomnia Scale scores were observed, accompanied by higher physical and mental component summary scores in MOS 36-item short-form health survey version 2 and a global World Health Organization Quality of Life Brief Version score. The laser group also showed significant improvements in QoL and sleep quality indicators. Additionally, pain levels decreased on the third day and after one month according to visual analogue scale. This study revealed the positive effects of 830nm laser on palm, KI 1 and ST 36 acupoints for improving the QoL and sleep quality in ESRD patients underwent HD treatment. The results suggest that 830nm laser applied to specific targets could be used as a complementary and alternative approach to increase the QoL and sleep quality in ESRD patients.

LITERATUR REVIEW PENGARUH RELAKSASI OTOT PROGRESIF TERHADAP KUALITAS TIDUR PASIEN HEMODIALISA

Chronic Kidney Failure sufferers experience sleep quality problems. Progressive muscle relaxation is useful for improving the sleep quality of hemodialysis patients. Objective: This literature review aims to determine the description of progressive muscle relaxation on the sleep quality of hemodialysis patients. Method: Search for research journals or literature studies via Google Scholar, PubMed, Science Direct and Springer pages published from 2018-2023. Then select, analyze and review several sources. Results: Progressive muscle relaxation affects the sleep quality of chronic kidney failure patients undergoing hemodialysis. Conclusion: Progressive muscle relaxation can be used to improve the sleep quality of hemodialysis patients. Suggestion: Patients undergoing hemodialysis can apply progressive muscle relaxation to improve sleep quality.&#x0D;

Pemberian Aromaterapi Lavender terhadap Kualitas Tidur Pasien Hemodialisis

This study aims to determine the effectiveness of lavender aromatherapy on hemodialysis patients' sleep quality. The method used is experimental intervention twice a week for four weeks. Before and after the intervention, sleep quality will be measured using the PSQI (Pittsburgh Sleep Quality Index) instrument. The results showed that (t = 22.789, p = 0.0001). 7.3% of the variable variation in the model was able to explain changes in the percentage of sleep quality (R2=0.073). Education variables (β=0.240, p=1.888), duration of HD (β=0.227, p=1.583), and the variable that is a predictor of sleep quality is gender (β=-0.006, p=0.421). In conclusion, there is a relationship between giving lavender aromatherapy and the sleep quality of hemodialysis patients compared to patients who did not receive lavender aromatherapy.&#x0D; &#x0D; Keywords: Lavender Aromatherapy, Hemodialysis, Sleep Quality

Hemodiyaliz Hastalarında Uyku Kalitesinin Ölüm Kaygısı, Depresyon ve Ağrı Üzerine Etkisi

Background/Aims: Poor sleep quality in hemodialysis patients causes a decrease in quality of life. In this study we aimed to investigate the relationship between sleep quality, and depression, death anxiety and perceived pain. Methods: A total of 101 patients with chronic kidney disease (CKD) under hemodialysis were included in this cross-sectional study. The assessment tools were Beck Depression Inventory (BDI), Death Anxiety Scale (DAS), Pittsburgh Sleep Quality Index (PSQI), and Visual Analogue Scale (VAS). Results: The mean age of the patients was 51.9±13.1. Ninety six (95%) patients had a PSQI score of 6 or above that indicates poor sleep quality. 64.4% of the patients had mild to severe depressive symptoms in terms of BDI. There were significant correlations between PSQI and DAS (r: 0.382), and VAS (r: 0.261), and BDI (r: 0.483). Conclusion: Poor sleep quality is a common problem in hemodialysis patients. Death anxiety, pain and depression are associated with poor sleep in hemodialysis patients. It is recommended to consider poor sleep quality to provide appropriate treatment.

FREQUENCY OF CHRONIC KIDNEY DISEASE ASSOCIATED PRURITUS AND ITS ASSOCIATION WITH SLEEP QUALITY IN HEMODIALYSIS PATIENTS

A cross-sectional study was conducted at the Department of Medicine, Khyber Teaching Hospital Peshawar, between November 2022 and April 2023. The study aimed to evaluate the frequency of pruritus associated with chronic kidney disease (CKD) and its correlation with sleep quality in hemodialysis patients. The study cohort comprised 55 individuals diagnosed with CKD, aged between 18 and 70, and of both genders. Chi-square and Independent Samples T-tests were used for statistical analysis, and a significance level of P &lt; 0.05 was considered statistically significant. The study found that 39 (70.9%) patients reported chronic kidney disease-associated pruritus. Among the pruritus patients, 7.7% reported no effect on their sleep, 43.6% reported occasional sleep, and 48.7% reported severe effects on sleep. The study showed a significant association between increasing age and pruritus (P = 0.0001) but no significant association between pruritus and gender (P = 0.23). The mean age of the patients was 40.8±14.12 years. The study concluded that the prevalence of pruritus in hemodialysis patients with chronic kidney disease was very high. Also, pruritus in individuals with chronic renal disease significantly correlated with sleep quality and advancing age among hemodialysis patients.

The Effect of Topical Application of Lavender Lipogel on Sleep Quality and Well-being in Patients Undergoing Maintenance Hemodialysis: A Randomized Clinical Trial

Background: Numerous studies have demonstrated the positive effects of lavender on the mental health of patients undergoing hemodialysis. Objectives: The present study aims to assess the effect of topical application of lipogel containing lavender essential oil on hemodialysis patients' sleep quality and well-being. Methods: The present randomized controlled clinical trial was conducted in a dialysis center in Iran. A total of 120 hemodialysis patients were assigned randomly to three groups (experimental, control, and placebo groups). In the experimental group, the lipogel containing lavender essential oil was applied on the back of the foot from the ankle to the toe. The same amount of lipogel without lavender essential oil was rubbed onto the patient’s feet in the same method in the placebo group. The control group received routine care. Yield Well-being Scale and Pittsburgh sleep quality index (PSQI) were used to assess the sense of well-being and sleep quality, respectively. Results: The statistical test showed no significant difference among the experimental, control, and placebo groups regarding the sense of well-being before (P = 0.421) and after the intervention (P = 0.378). The groups (experimental, control, and placebo) did not differ significantly before the intervention in terms of the total score of sleep quality (P = 0.527), but a significant difference was observed among them after the intervention (P = 0.017). Conclusions: The lipogel containing the lavender essential oil is a cost-effective and easy method that can improve the sleep quality of hemodialysis patients. To confirm the present findings, additional studies are warranted.

Comparing the Effects of Acupressure and Clonazepam Tablets on Sleep Quality of Hemodialysis Patients: A Randomized Controlled Trial.

Objective: The current study aimed to compare the impact of acupressure and clonazepam tablets on the quality of sleep in hemodialysis patients in light of the rising prevalence of chronic kidney disease (CKD), the high prevalence of sleep disturbance in these patients, and the side effects of hypnotic drugs. Method : A total of 60 patients were selected for this randomized, controlled clinical trial and randomly assigned to two groups. For two weeks during the researcher's evening shift, one group received acupressure (six spots bilaterally for three minutes each day). The opposing group was administered clonazepam tablets (0.5 mg) for two weeks. The Pittsburgh Sleep Quality Index (PSQI), which measures sleep quality, was used to compare sleep in the two groups before and after the intervention. Results: There was no statistically significant difference between the two groups prior to the intervention (P = 0.75) in terms of the mean pre-intervention PSQI scores for the acupressure and clonazepam groups, which were 15.83 ± 1.51 and 16.17 ± 0.91, respectively. However, the average PSQI scores after the intervention in the clonazepam and acupressure groups were 13.25 ± 2.88 and 8.97 ± 4.29, respectively, indicating a statistically significant difference (P < 0.0001). Both the acupressure and the clonazepam groups showed improvements in their post-intervention sleep quality among the patients. However, when the percentage changed in the mean scores of the total score and all of the PSQI components were calculated for each group, it became clear that acupressure was more effective at enhancing sleep than clonazepam tablets. Conclusion: The findings of the present investigation demonstrate that acupressure has a greater impact on patients' sleep quality compared to clonazepam tablets. Depending on the circumstances, acupressure can be used as a simple, safe, and non-drug way to enhance hemodialysis patients' quality of sleep.

Comparison of Sleep Quality in Kidney Transplant Recipients vs. Hemodialysis Patients: A Cross-Sectional Study

Background and Objective: Determining sleep quality in hemodialysis patients and kidney transplant recipients can provide valuable clinical information for planning treatment and care in this group of patients. Thus, we compared sleep quality between hemodialysis patients and kidney transplant recipients.&#x0D; Materials and Methods: In this cross-sectional study, 60 transplant patients and 60 hemodialysis patients were selected using convenience sampling method. The Pittsburgh Sleep Quality Index (PSQI) with 89% validity and 86% reliability was used to assess patients' sleep quality.&#x0D; Results: The mean PSQI score was higher in the hemodialysis group (7.78) than the kidney transplantation group (6.15). This indicates that the sleep quality in hemodialysis patients is worse than in patients after kidney transplantation (P = 0.028). The frequency of poor sleep quality in hemodialysis patients was higher than in kidney transplant patients [50(83.3%) vs. 37(61.7%)].&#x0D; Conclusion: The results of this study indicate that kidney transplant recipients have better sleep quality than hemodialysis patients.

The Effectiveness of Different Types of Massages on Sleep Quality in Hemodialysis Patients: A Literature Study

Hemodialysis can cause disturbance in sleep. Sleep disorders cause immune system disorders and decreased sleep quality. Low sleep quality leads to poor quality of life resulting in premature death and negative impacts on the individual’s immune response which can lead to the development of cardiovascular diseases, which is the leading cause of death in patients with kidney disease. This study aimed to identify and describe the effectiveness of different types of massages in improving the sleep quality of hemodialysis patients. This was a literature study. We examined a journal that focused on massage therapy in patients undergoing hemodialysis. The observed variable was the sleep quality of hemodialysis patients. Data were analyzed using the qualitative descriptive analysis method. The results showed that hand massage therapy, foot massage therapy and back massage therapy were effective in improving the sleep quality of hemodialysis patients. However, massage therapy in the form of acupressure is less effective in improving sleep quality. Based on the results, aromatherapy massage therapy on the feet was the most effective. The most influential type of massage was massage using aromatherapy. Massages of the hands, feet, and back also affected the sleep of hemodialysis patients but only slightly affects the quality of sleep.&#x0D; Keywords: massage, hemodialysis, accupressure, aromatherapy

Effects of perceived stress, self-acceptance and social support on insomnia in hemodialysis patients: A cross-sectional study

ObjectiveThe aim of this study was to explore the influence of perceived stress, self-acceptance and social support on insomnia among hemodialysis patients in China. MethodsA cross-sectional study was conducted in Gansu, China, from May 2022 to July 2022. The Chinese Perceived Stress Scales (CPSS), Athens Insomnia Scale (AIS), Self-acceptance Questionnaire (SAQ), and Perceived Social Support Scale (PSSS) were evaluated in 610 hemodialysis patients. ResultsThe prevalence of insomnia among hemodialysis patients was 40.7% in this study. Insomnia was positively correlated with perceived stress (r = 0.742, P < 0.01), and negatively correlated with self-acceptance (r = −0.531, P < 0.01) and social support (r = −0.574, P < 0.01). Self-acceptance played a mediating role in perceived stress and insomnia, with the mediating effect accounting for 13.8% of the total effect. Social support played a moderating role in perceived stress and insomnia (β = −0.008, t = −5.112, P < 0.001). ConclusionsThe results of this study enrich the research on the influencing factors of insomnia in hemodialysis patients and provide theoretical basis and practical guidance for improving the sleep quality of hemodialysis patients.

Association of dietary fiber with subjective sleep quality in hemodialysis patients: a cross-sectional study in China

Background Poor sleep quality is a common problem among hemodialysis (HD) patients. Dietary fiber is a key component of a healthy diet and is beneficial for a variety of health outcomes; however, evidence of an association between dietary fiber consumption and subjective sleep quality has not been established among HD patients. Therefore, we determined the association between dietary fiber consumption and the subjective sleep quality in Chinese maintenance HD patients, taking into account fiber type and source. Methods Dietary intake was assessed with a validated food frequency questionnaire in a cross-sectional study including 741 maintenance HD patients between December 2021 and January 2022. The daily intake of dietary fiber was categorized into three groups. The lowest tertile was used as the reference category. Sleep quality of patients was accurately calculated using the Pittsburgh sleep quality index standard questionnaire. Multivariable logistic regression model and restricted cubic spline analysis were performed to assess the relationship between dietary fiber consumption and poor sleep quality. Results Compared with the lowest tertile group of dietary fiber intake, the highest tertile group had a lower prevalence of poor sleep quality. After adjustment for potential confounders, a higher intake of total dietary fiber (ORtertile 3 (T3) to tertile 1 (T1)= 0.51, 95% CI: 0.31–0.85), total insoluble dietary fiber (ORT3 to T1 =0.54, 95% CI: 0.33–0.89), and soluble dietary fiber in vegetables (ORT3 to T1 =0.61, 95% CI: 0.40–0.93) were associated with a lower prevalence of poor sleep quality. Furthermore, significant linear trends were also observed (p < 0.05). No significant interactions were observed in subgroup analyses. Conclusion A higher intake of dietary fiber was inversely associated with the poor sleep quality. These findings support the current recommendations that dietary fiber is essential for health and well-being.

The Effect of Family-Centered and Peer-Centered Education on the Sleep Quality of Hemodialysis Patients: A Randomized Clinical Trial.

Sleep disorders in hemodialysis patients are of high prevalence affecting the lives of these patients. The present study was conducted to investigate the effect of family-centered and peer-centered education on the sleep quality of hemodialysis patients. In this controlled clinical trial, 90 patients were randomly assigned to three groups (control, family-centered, and peer-centered). All three groups completed Pittsburgh Sleep Quality Index before the intervention. The intervention included five training sessions conducted by the researcher according to the patients' needs to improve their sleep quality. Routine ward interventions were performed for the control group. At the end of the study, the Pittsburgh Sleep Quality Index was completed by all three groups once again. Data were collected and analyzed using SPSS version 24 software and statistical tests. No significant difference was found between the two intervention and control groups regarding demographic variables and variables related to sleep quality before the intervention (p < .05). However, based on the results of the Wilcoxon test, there was a statistically significant difference between the mean rank of sleep quality in the intervention and control groups after the intervention (p-value = .008), indicating that sleep hygiene education was effective in the two intervention groups. According to the findings, the mean rank of sleep quality in the two intervention groups was significant after the training, indicating the effectiveness of family-centered and peer-centered education. Accordingly, medical healthcare managers, policymakers, and planners, including nurses, are recommended to employ these convenient, safe, and cost-free training methods and provide better sleep quality and more comfort to patients by spending a short period of time for training.

Effects of Aromatherapy with Jasmine Essential Oil on the Sleep Quality of Hemodialysis Patients

Introduction: Poor sleep quality is a common problem among hemodialysis patients. Aromatherapy has few complications and is an effective approach to this problem. Objective: The present study aimed to assess the effect of aromatherapy with jasmine essential oil on the sleep quality of hemodialysis patients. Materials and Methods: This double-group clinical trial was conducted on 54 patients undergoing hemodialysis with poor sleep quality living in Sabzevar City, Iran, in 2021. The patients were divided into the intervention and control groups (21 in the intervention and 25 in control group) using the random allocation method with permuted blocks. The study data were collected using a demographic questionnaire and the Pittsburgh Sleep Quality Index (PSQI), completed at the beginning of the study. The patients in the intervention group inhaled a piece of cotton smeared with jasmine essential oil every night for one month. The concentration of jasmine extract was 70%, the duration of inhalation was about 7 hours, and the distance between the place of cotton soaked in jasmine and the patient’s nose was 30 cm. Afterwards, the PSQI was completed again. Data analysis was performed using descriptive indices, the Chi-square test, the independent t-test, paired t-test, the Fisher exact test, and univariate analysis of variance. P Values less than 0.05 were considered significant. Results: The patients were 18-70 years old. Comparing demographic data between the two study groups showed no significant difference in terms of age, gender, marital status, employment status, and education. In the intervention group, the Mean±SD of sleep quality decreased from 9.90±2.70 to 6.16±2.15 after aroma therapy. In the control group, the score decreased from 8.48±2.98 to 8.16±2.68. The analysis of variance for overall sleep quality after the intervention by modulating the effect of overall sleep quality before the intervention showed a significant difference among the groups in terms of overall sleep quality after the intervention (the effect size=0.24, P=0.001). Conclusion: According to the results, aromatherapy with jasmine essential oil could enhance the sleep quality and sleep duration of the patient’s undergoing hemodialysis.

Effect of predialysis fluid overload on sleep quality in hemodialysis patients

Background Sleep disorders are common among end-stage renal disease patients undergoing hemodialysis (HD). The etiology of sleep disorders in these patients is known to be multifactorial. However, the role of hydration status in sleep disorders in HD patients is not well studied. Therefore, our aim was to study the effect of predialysis fluid overload on sleep quality in HD patients. Patients and methods This cross-sectional study included 100 prevalent HD patients from the HD unit of El Sahel Teaching Hospital. Fluid status and fluid compartments [total body water), extracellular water (ECW),and overhydration (OH) index] were analyzed by a portable whole-body bioimpedance spectroscopy (body composition monitor) before a mid-week dialysis session. OH was defined as OH/ECW% more than or equal to 15%. HD patients were then classified into two groups: group 1 (normohydrated) and group 2 (overhydrated) according to the relative OH index (OH/ECW%). Sleep quality was assessed in all patients by the Pittsburgh Sleep Quality Index (PSQI) questionnaire. Patients with concurrent diagnosis of either obstructive sleep apnea or psychiatric disorder and patients on any medications that affect the sleep pattern were excluded. Results Our study included 100 HD patients (49 male, 51 female; mean age, 49.3 ± 11); 42 (42%) patients had OH (i.e. group 2). Poor sleep quality (defined as PSQI score ≥5) was reported in 57% (n=57) of HD patients included in our study. Poor sleep quality was significantly higher in the HD patients with OH (group 2). Total PSQI scores were significantly higher in overhydrated patients (group 2) compared with normohydrated patients (group 1) (7.92 ± 3.32 vs. 4.83 ± 2.27, P≤0.001). The component scores 1, 2, 3, 4, 6, and 7 of the PSQI showed significant higher values (i.e. poor sleep quality) in overhydrated patients (group 2). Moreover, there was significant positive correlation between total PSQI score both of OH (r=0.259, P=0.009) and OH index (OH/ECW%) (r=0.283, P=0.004) in all HD patients included in the study. Conclusion We may conclude from our study that sleep disorders are prevalent in HD patients. Predialysis fluid overload in HD patients may be associated significantly with poor sleep quality.

The effect of lavender essential oil aromatherapy on sleep quality in hemodialysis patients

Hemodialysis is a long-term therapy that must be undertaken by patients with chronic kidney disease. Patients who undergoing therapy for a very long time will have an impact on the patient's psychology. One of the psychological effects that arise is a sleep disorder. Poor sleep quality can lead to physiological changes, the endocrine system, cardiovascular system, and immune and nervous systems. To overcome sleep disorders in hemodialysis patients, non-pharmacological options can be used, namely Lavender Essential Oil Aromatherapy via inhalation. The purpose of this study was to determine the effect of Lavender Essential Oil Aromatherapy on Sleep Quality in Hemodialysis Patients. The study was conducted on 32 hemodialysis patients, divided into two groups, there are 16 intervention groups and 16 control groups. The intervention was carried out for 3 times of administration during intra-hemodialysis. The instrument used is the Pittsburgh Sleep Quality Index (PSQI) applied pre and post-test. Test data analysis using the independent samples test showed that there was a difference in the average score for sleep quality with a p-value of 0.000, it means that there was an increase in sleep quality in patients undergoing hemodialysis for intervention groups. Lavender Essential Oil Aromatherapy can be applied as an effective nursing intervention to overcome sleep quality disorders in patients undergoing hemodialysis. Abstrak: Hemodialisis merupakan terapi jangka panjang yang harus dilakukan oleh pasien dengan penyakit ginjal kronik. Pasien yang menjalani terapi dalam waktu yang sangat lama akan berdampak pada psikologi pasien. Salah satu dampak psikologis yang muncul adalah gangguan tidur. Kualitas tidur yang buruk dapat menyebabkan perubahan fisiologis, sistem endokrin, sistem kardiovaskular, sistem kekebalan dan saraf. Untuk mengatasi gangguan tidur pada pasien hemodialisa dapat digunakan pilihan nonfarmakologi yaitu Aromaterapi Minyak Atsiri Lavender melalui inhalasi. Tujuan penelitian ini adalah untuk mengetahui pengaruh Aromaterapi Minyak Atsiri Lavender terhadap Kualitas Tidur pada Pasien Hemodialisis. Penelitian dilakukan pada 32 pasien hemodialisa yang terbagi menjadi dua kelompok yaitu 16 kelompok intervensi dan 16 kelompok kontrol. Intervensi dilakukan selama 3 kali pemberian selama intra hemodialisis. Instrumen yang digunakan adalah Pittsburgh Sleep Quality Index (PSQI) yang diterapkan sebelum dan sesudah intervensi. Analisis data uji dengan menggunakan independent sample test menunjukkan bahwa terdapat perbedaan rata-rata skor kualitas tidur dengan nilai p value 0,000 artinya terjadi peningkatan kualitas tidur pada pasien yang menjalani hemodialisis kelompok intervensi. Aromaterapi Minyak Atsiri Lavender dapat diterapkan sebagai intervensi keperawatan yang efektif untuk mengatasi gangguan kualitas tidur pada pasien yang menjalani hemodialisis.

The Epidemiology of Chronic Kidney Disease-Related Pruritus and its Effect with Sleep Quality in Hemodialysis Patients in Pakistan A Cross-Sectional Study

A glomerular filtration rate of less than 60 ml/min/1.73 m2 for more than three months is the medical definition of chronic kidney disease (CKD) caused by damaged kidneys. The incidence of chronic kidney disease, which can be fatal if left untreated, has been rising for the past 30 years. An unpleasant condition, Pruritus due to chronic renal disease causes itching and decreases the quality of sleep. This study aims to examine the factors associated with Pruritus in CKD patients on maintenance hemodialysis and their impact on sleep quality. Duration and Place: Since 01/01 2019 and ending in 30/06/2019 that year, I will be working as a Post graduate trainee Nephrology in the Nephrology Department at the Institute of Kidney Diseases in Peshawar. Methodology: The department of Nephrology Institute of kidney diseases provided 120 patients with the chronic renal illness. Patients with chronic kidney disease who experienced Pruritus and sleep disruption were included in the study, but those with rashes and Pruritus unrelated to CKD were not. All patients were questioned about their age, gender, typical sleeping habits, illness severity, poor sleep quality, and the location of any pruritus they experienced. Results: CKD-associated This is how pruritis was dispersed: Eighty-one Percent of patients were older than 90, while the remaining 24 percent were younger. Only 43% of those diagnosed with Pruritus reported it affecting their ability to sleep, while 57% reported no such disruptions; also, only 31% of those diagnosed were female, and 74% were male. About 56 percent of those suffering from Pruritus have it quite seriously, whereas 44 percent do not. 62% of Pruritus people experience it on their trunks, compared to 38% elsewhere. A high degree of Pruritus was associated with the female gender, affected body parts, and lack of sleep. Conclusion: Pruritus (sometimes called "uremic pruritus") is the most prevalent skin symptom among persons with ESRD. Despite the absence of evidence linking it to uremia, a significant connection exists in men over 45, causes sleep disruption, and predominates in the trunk. Keywords: CKD-Related Pruritus, Effect, Sleep Quality, Hemodialysis

The Effects of Inhalational Lavender Essential Oil Aromatherapy on Sleep Quality in Hemodialysis Patients: A Before-and-After-Intervention Trial.

One of the most essential physical prerequisites for human survival is sleep. Patients undergoing hemodialysis often experience a lack of sleep, and it is one of the decisive variables in dialysis patients' quality of life. The objective of this study was to assess the effects of inhaling lavender essential oil on sleep quality in hemodialysis patients. A total of 30 patients were enrolled in the before-and-after intervention trial, which took place in a tertiary care hospital's dialysis unit. The study participants were selected using the purposive sampling technique and they received lavender oil inhalation therapy. The sleep quality was measured using the Pittsburgh Sleep Quality Index. The mean age of the participants was 55.11 (SD = 8.45) years. The mean posttherapy Pittsburgh Global Sleep Quality Index score was 8.8 ± 1.89 compared with the pretherapy score of 14.73 ± 1.53. Patients undergoing hemodialysis experienced a substantial improvement in sleep quality ( P < .05). Aromatherapy using lavender oil is effective in enhancing sleep quality in hemodialysis patients.

COVID-19 pandemic: depression and sleep quality in hemodialysis patients

Introduction: Depression and sleep disturbance are prevalent comorbidities in hemodialysis patients. This study aimed to investigate the relationship between depressive mood, sleep disturbance, and the fear of COVID-19 Scale in hemodialysis patients during the pandemic process.&#x0D; Material and Method: 116 hemodialysis patients followed up in our clinic and volunteered were included in the study. The socio-demographic characteristics of the patients and the laboratory test results studied in their routine follow-ups were obtained from the file records. Beck Depression Inventory (BDI), Pittsburgh Sleep Quality Index (PSQI), and the Fear of COVID-19 Scale (FCV-19S) were applied through face-to-face interviews.&#x0D; Results: 116 patients (70 males, 46 females) with a hemodialysis duration of 40 months (13-295) and age of 60.2±13.3 years were included in the study. The patients were divided into two groups according to their PSQI score as good sleeper (PSQI ≤ 5, n=66) and poor sleeper (PSQI &gt;5, n=50). When evaluated by gender 28 (56%) female patients were in the poor sleeper group (p=0.002). Dialysis time was longer, BDI score and FCV-19 scale were higher in the poor sleeper group than the good sleeper group. PSQI score was positively correlated with dialysis time (r=0.259 p=0.005), BDI score (r=0.279 p=0.002), and FCV-19 scale (r=0.304 p=0.001). In the Multiple Logistic Regression analysis established to evaluate the risk factors affecting sleep quality, BDI was determined as an independent risk factor for poor sleep (OR: 1.084, 95%CI [1.021-1.152], p=0.008). Subjects were divided into two groups according to their BDI scores as those with depressive mood (BDI score ≥ 17, n=47) (40.5%) and those without (BDI score &lt; 17, n=69) (59.5%). Thirty-two of the cases with depressive mood were women (68.1%) (p

POS-601 IMPROVEMENT IN SLEEP QUALITY FROM REDUCTION OF ITCH INTENSITY IN PATIENTS WITH MODERATE-TO-SEVERE PRURITUS UNDERGOING HEMODIALYSIS

Chronic kidney disease-associated pruritus (CKD-aP) is a common condition in patients with CKD undergoing hemodialysis (HD). Night-time pruritus may be a particularly burdensome symptom: In CKD-aP patients this results in poor sleep quality, an important marker of worse health-related quality of life (QoL). In phase 3 trials in patients with moderate-to-severe CKD-aP, difelikefalin (a peripherally restricted kappa-opioid receptor agonist), demonstrated significant improvements in itch intensity versus placebo at week 12, and improvements in sleep quality and itch-related QoL. The aim of the study was to evaluate the impact of reduced itch intensity on sleep quality among HD patients treated with difelikefalin or placebo in the KALM-1 and KALM-2 Phase 3 clinical trials. This post-hoc analysis used pooled data for all patients. Improvement from baseline to week 12 in itch intensity was evaluated by weekly mean of the 24-hour Worst Itching Intensity Numerical Rating Scale (WI-NRS) score (range 0 [no itch] to 10 [worst itch imaginable]). Change in sleep quality was assessed by the 5-D Itch scale sleep disability question (1 [never affects sleep] to 5 [delays falling asleep and frequently wakes me up at night]). Spearman’s correlation analysis was performed. Patients with a clinically meaningful (≥3-point) reduction in WI-NRS score had significantly greater improvements in mean 5-D Itch sleep disability question score (−1.5 vs −0.6 for <3-point WI-NRS score reduction; p<0.0001) from baseline to week 12 (n=709) (Figure ). A moderate correlation was observed between WI-NRS and 5-D Itch sleep disability question scores at week 12 (r =0.499, 95% confidence interval 0.442, 0.552). A significant improvement was also observed at the first assessment of sleep quality (4 weeks) for patients with a ≥3-point (vs <3-point) reduction in WI-NRS score (−1.2 vs −0.4, p<0.0001, n=761). Reduction of itch intensity correlates with improvement in sleep quality in HD patients.