Background/Aims: Poor sleep quality in hemodialysis patients causes a decrease in quality of life. In this study we aimed to investigate the relationship between sleep quality, and depression, death anxiety and perceived pain. Methods: A total of 101 patients with chronic kidney disease (CKD) under hemodialysis were included in this cross-sectional study. The assessment tools were Beck Depression Inventory (BDI), Death Anxiety Scale (DAS), Pittsburgh Sleep Quality Index (PSQI), and Visual Analogue Scale (VAS). Results: The mean age of the patients was 51.9±13.1. Ninety six (95%) patients had a PSQI score of 6 or above that indicates poor sleep quality. 64.4% of the patients had mild to severe depressive symptoms in terms of BDI. There were significant correlations between PSQI and DAS (r: 0.382), and VAS (r: 0.261), and BDI (r: 0.483). Conclusion: Poor sleep quality is a common problem in hemodialysis patients. Death anxiety, pain and depression are associated with poor sleep in hemodialysis patients. It is recommended to consider poor sleep quality to provide appropriate treatment.