Sleep Apnea Syndrome Subjects Research Articles

Sleep Apnea Syndrome Detection Based on Degree of Convexity of Logarithmic Spectrum Calculated from Overnight Bio-vibration Data of Mattress Sensor.

This paper proposes the novel Sleep Apnea Syndrome (SAS) detection method based on the frequency analysis of the overnight bio-vibration data acquired from mattress sensor. Concretely, this paper designs the index called Degree of Convexity of the Logarithmic Spectrum (DCLS), which quantifies the degree of convexity by computing the difference between the waveform of the averaged logarithmic spectrum and the waveform of its approximation formula, and employs it to detect SAS. Through the human subject experiment on the SAS detection, the following implications have been revealed: (1) the SAS subjects tend to have the large density around 3Hz, and the average of DCLS in SAS subjects and healthy subjects are 98.6±10.1 and 48.2±6.8 respectively, which succeeds to correctly separate the nine SAS subjects and the nine healthy subjects; and (2) the characteristics of the WAKE stage are different between the SAS and healthy subjects.

The prevalence of glaucoma in patients with sleep apnea syndrome: same as in the general population

Purpose An association of glaucoma and sleep apnea syndrome (SAS) has been widely reported. We investigated the largest group of patients with SAS thus far to determine the prevalence of glaucoma among these patients. Design Cross-sectional study. Methods An institutional study. Study population A total of 228 patients with SAS. Observation procedures Sleep studies determined the respiratory disturbance index (RDI) during night sleep. Ocular examination included intraocular pressure (IOP) measurement, optic disk evaluation, and Humphrey visual field examination. Main outcome measures The SAS was diagnosed as an RDI > 10. The RDI was graded to determine the severity of SAS: mild (RDI, 10–19), moderate (RDI, 20–39), and severe (RDI > 40). Open-angle glaucoma was diagnosed when a glaucomatous visual field defect matched the optic disk changes, irrespective of IOP levels. Results Nineteen participants had mild SAS (mean ± standard deviation, RDI = 15 ± 3), 129 had moderate SAS (RDI = 28 ± 5), and 80 had severe SAS (RDI = 54 ± 11). Open-angle glaucoma was found in five SAS subjects, a prevalence of 2% (95% confidence interval, 0.7% to 5%). There was no correlation between RDI and the presence of glaucoma (chi-square = 1.18; degrees of freedom = 2; P = .6) or between the RDI and the IOP (r = −0.067; P = .316). Conclusion The prevalence of glaucoma in SAS patients was similar to that in the general Caucasian population.

Syndrome d'apnées au cours du sommeil ; effet de la chlorimipramine chez des sujets a poids stable

Beneficial effects have been attributed to Chlorimipramine in the treatment of sleep apnea syndrome (SAS). However, there were no quantitative evaluations of these effects. Polygraphic studies were made before and after chlorimipramine treatment (75 mg per day for 3 to 16 months). The 3 SAS subjects, whose weight remained stable throughout the course of treatment, showed no evidence of reduced hypopnea and apnea during sleep.