The concept of the Thai family has shifted from the traditional family to families of various forms, such as single-parent families, same-sex families, skipped-generation families, and one-person households, which affects not only mental health, but future relationships of the children. This research aimed to analyze the factors that contribute to family strengths in the context of Generation Alpha and develop a measurement model tailored to a Thai context. The sample consisted of parents and caregivers of Generation Alpha, divided into two sections, with 521 participants for exploratory factor analysis and 508 participants for confirmatory factor analysis. Using stratified random sampling, data were collected via questionnaires distributed across four regions of Thailand. The discrimination index ranged from 0.280-0.896, with a Cronbach's alpha of 0.952. The results revealed a measurement model consisting of five key factors contributing to family strengths. The factor with the highest score was positive relationships, with a factor loading of 0.92. Additional factors included technology and media literacy, parental roles, good attributes, and mental immunity, with a factor loading of 0.80, 0.74, 0.55, and 0.44, respectively. The measurement model of family strengths for Generation Alpha in the Thai context was found to be consistent with the empirical data. These findings suggest that understanding these family strengths can significantly enhance the well-being of both Generation Alpha and their family members.