Skin-picking Disorder Research Articles

Mental Health Providers’ Knowledge of Trichotillomania and Skin Picking Disorder, and Their Treatment

Mental Health Providers’ Knowledge of Trichotillomania and Skin Picking Disorder, and Their Treatment

Appearance-related concerns in individuals with pathological skin picking-a comparison with individuals with dermatological conditions and skin-healthy controls.

Pathological skin picking (PSP) is an excessive behavior which characterizes Skin Picking Disorder. Individuals repeatedly pick their skin and cause skin lesions, but are unable to control the behavior, which can cause severe distress. Visible self-inflicted skin lesions can additionally affect individuals with PSP due to emerging appearance-related concerns. However, these concerns and their role in PSP have hardly been studied, especially not in comparison with individuals with dermatological conditions and skin-healthy controls. The present cross-sectional study (n = 453, 83.9% female, 15.9% male, 0.2% diverse) aimed at analyzing appearance-related concerns and mental health outcomes between four groups: Individuals with PSP and dermatological conditions (SP/DC; n = 83), PSP without dermatological conditions (SP; n = 56), dermatological conditions without PSP (DC; n = 176) and skin-healthy controls (SH, n = 138). We compared questionnaire data on dysmorphic concerns, appearance-based rejection sensitivity, and body dysmorphic symptoms, as well as PSP-symptoms and mental health outcomes (depression, anxiety, and self-esteem) between groups. The analyses showed a significant multivariate group effect in the appearance-related variables, F(6, 896) = 19.92, Wilks' Λ = 0.78, p < 0.001, and mental health outcomes, F(6, 896) = 16.24, Wilks' Λ = 0.81, p < 0.001. The SP/DC group had the strongest appearance-related concerns and mental health impairments, followed by the SP group, the DC group and the SH group. The SP/DC group and SP group only differed significantly with regard to dysmorphic concerns, but not in other variables. The DC group was less affected but still showed higher dysmorphic concerns and mental health impairments than skin-healthy controls. In contrast to the PSP groups, the other two groups did not exceed clinically relevant cut-off scores. The present study shows that individuals with PSP exhibit strong appearance-related concerns, regardless of the presence or absence of underlying or comorbid dermatological conditions. These findings shed new light on the importance of appearance-related concerns in Skin Picking Disorder and the role of PSP as a potentially overlooked risk factor in dermatological patients. Therefore, appearance-related concerns should be explicitly addressed in dermatological and psychotherapeutic settings. Future studies should also include longitudinal and experimental analyses to more clearly classify the role of appearance-related concerns in the etiology of PSP and Skin Picking Disorder.

Temperament in trichotillomania and skin picking disorder.

Trichotillomania (TTM) and skin picking disorder (SPD) result in significant psychosocial burden. Despite this burden, however, risk factors related to the development of these disorders remain unclear. The present study assessed temperament in a well-characterized sample of adults with TTM or SPD. A total of 202 adults age 18 to 65 were enrolled; 44 had TTM, 30 had SPD, and 128 served as controls. Participants completed the self-report Tridimensional Personality Questionnaire (TPQ) to examine the severity of TTM and SPD symptoms, quality of life, and temperament. Group differences were characterized and correlations with other measures were examined. Compared to controls, those with TTM or SPD scored significantly higher on harm avoidance and its subscales, with TTM associated with higher scores than SPD. Those with TTM or SPD scored significantly higher on only 1 measure of novelty seeking (extravagance). Higher TPQ harm avoidance correlated with worse hair pulling severity and worse quality of life. The temperament traits of participants with TTM or SPD differed in significant ways from controls; those with TTM or SPD generally demonstrated similar trait profiles. A dimensional approach to the personalities of those with TTM or SPD may offer insight and provide clues to treatment strategies.

Impaired cognitive flexibility across psychiatric disorders.

Problems with cognitive flexibility have been associated with multiple psychiatric disorders, but there has been little understanding of how cognitive flexibility compares across these disorders. This study examined problems of cognitive flexibility in young adults across a range of psychiatric disorders using a validated computerized trans-diagnostic flexibility paradigm. We hypothesized that obsessive-compulsive spectrum disorders (eg, obsessive-compulsive disorder, trichotillomania, and skin-picking disorder) would be associated with pronounced flexibility problems as they are most often associated with irrational or purposeless repetitive behaviors. A total of 576 nontreatment seeking participants (aged 18-29years) were enrolled from general community settings, provided demographic information, and underwent structured clinical assessments. Each participant undertook the intra-extra-dimensional task, a validated computerized test measuring set-shifting ability. The specific measures of interest were total errors on the task and performance on the extra-dimensional (ED) shift, which reflects the ability to inhibit and shift attention away from one stimulus dimension to another. Participants with depression and PTSD had elevated total errors on the task with moderate effect sizes; and those with the following had deficits of small effect size: generalized anxiety disorder (GAD), obsessive-compulsive disorder (OCD), antisocial personality disorder, and binge-eating disorder. For ED errors, participants with PTSD, GAD, and binge-eating disorder exhibited deficits with medium effect sizes; those with the following had small effect size deficits: depression, social anxiety disorder, OCD, substance dependence, antisocial personality disorder, and gambling disorder. These data indicate cognitive flexibility deficits occur across a range of mental disorders. Future work should explore whether these deficits can be ameliorated with novel treatment interventions.

Memantine May Reduce Hair-Pulling, Skin Picking

Memantine May Reduce Hair-Pulling, Skin Picking

Measuring symptoms of obsessive-compulsive and related disorders using a single dimensional self-report scale.

Obsessions and compulsions are heterogenous but can be classified into obsessive-compulsive disorder (OCD), body dysmorphic disorder (BDD), hoarding disorder (HD), hair-pulling disorder (HPD), and skin-picking disorder (SPD). OCD is in itself heterogenous, with symptoms clustering around four major symptom dimensions: contamination/cleaning, symmetry/ordering, taboo obsessions, and harm/checking. No single self-report scale captures the full heterogeneity of OCD and related disorders, limiting assessment in clinical practice and research on nosological relations among the disorders. To provide a single self-report scale of OCD and related disorders that respects the heterogeneity of OCD, we expanded the DSM-5-based Obsessive-Compulsive and Related Disorders-Dimensional Scales (OCRD-D) so that is also includes the four major symptom dimensions of OCD. A psychometric evaluation and an exploration of the overarching relations among the dimensions were conducted using an online survey which was completed by 1,454 Spanish adolescents and adults (age span = 15-74 years). Approximately 8 months after the initial survey, 416 participants completed the scale again. The expanded scale showed excellent internal psychometric properties, adequate test-retest correlations, known groups validity, and correlations in the expected directions with well-being, depression/anxiety symptoms, and satisfaction with life. The higher-order structure of the measure indicated that harm/checking and taboo obsessions formed a common disturbing thoughts factor and that HPD and SPD formed a common body-focused repetitive behaviors factor. The expanded OCRD-D (OCRD-D-E) shows promise as a unified way to assess symptoms across the major symptom dimensions of OCD and related disorders. The measure may be useful in clinical practice (e.g., screening) and research, but more research on construct validity, incremental validity, and clinical utility is needed.

Prevalence and Correlates of Hair Pulling Disorder and Skin Picking Disorder in an Acute Psychiatric Sample.

Hair pulling disorder (HPD; trichotillomania) and skin picking disorder (SPD; excoriation disorder) are understudied psychiatric disorders. The aim of this study was to examine the prevalence and correlates of HPD and SPD in an acute psychiatric sample. Semistructured interviews and self-report measures were administered to patients in a psychiatric partial hospital (N = 599). The past-month prevalence of HPD and SPD was 2.3% and 9%, respectively. HPD and SPD had highly similar clinical characteristics and a strong co-occurrence. Patients with HPD/SPD were significantly younger than other patients and more likely to be female. Logistic regression controlling for age and sex showed that diagnosis of HPD/SPD was not significantly associated with suicidal ideation, suicidal behaviors, nonsuicidal self-injury, or emotional disorder diagnoses (e.g., borderline personality disorder, major depressive disorder). HPD/SPD status was significantly associated with an increased risk of generalized anxiety disorder. However, patients with HPD/SPD did not differ from other patients on self-report measures of generalized anxiety, depression, and distress intolerance. HPD and SPD are common and frequently co-occurring disorders in psychiatric settings.

Skin Excoriation Disorder with Comorbid Schizophrenia

Skin-picking Disorder (SPD) or Excoriation Disorder is an Obsessive Compulsive Spectrum Disorder where one compulsively picks at his skin. Obsessive Compulsive Spectrum Disorder is commonly seen to be associated with Schizophrenia

Trichotillomania, Skin Picking Disorder, and Different Aspects of Impulsivity: A Systematic Review

Trichotillomania and skin picking disorder are psychiatric disorders with body-focused repetitive behaviors (BFRB). Impulsivity is considered to have a role in the etiology of BFRB. Various methods have been implemented to demonstrate different aspects of impulsivity due to its multidimensional construct. This systematic review aimed to synthesize existing studies to examine different aspects of impulsivity in BFRB. A systematic literature review was conducted in January 2021. Some original studies evaluating the relationship between impulsivity and trichotillomania or skin picking disorder were obtained. Twenty studies were examined after a systematic search of the MEDLINE database. The findings revealed that impulsivity was investigated using a self-report scale in five studies and behavioral tasks in 18 studies. Five studies reported higher trait impulsivity in BFRB with different self-report scales. Differences have been found in the urgency, motor, and attentional subscales. Eight studies measuring motor impulsivity (response inhibition) with behavioral tasks showed higher impulsivity in BFRB and its subgroups. Three studies evaluating cognitive impulsivity with behavioral tasks reported that BFRB is not related to reflection and decision-making impulsivity. However, functional alterations in BFRB patients fMRI, during a choice impulsivity task, were shown in one study only. Different aspects of impulsivity are associated with BFRB. The most commonly identified impairment with behavioral tasks, response inhibition impairment, is conceptually similar to the urgency and motor subscales determined by self-report scales. These results support the patients' self-reports and explain the patients' tendency to act rashly under an increasing sense of tension. However, further studies should be conducted to make a definite conclusion about cognitive impulsivity characteristics of BFRB patients. [ Psychiatr Ann . 2022;52(12):527–540.]

Prevalence of and Risk Factors for Skin Picking Disorder Symptoms Among Adults in an Arab Middle Eastern Population: A Cross-Sectional Study.

Skin Picking Disorder (SPD) is a skin-related disease, also recognized as psychogenic excoriation, dermatillomania, or excoriation disorder. SPD is defined as a habitual picking of skin, which in turn harms skin tissue. Given the paucity of information on SPD symptoms, their prevalence, and risk factors in Saudi Arabia, the present study seeks to fill this gap by investigating these factors in a community sample from Jeddah. This descriptive cross-sectional study was conducted in the city of Jeddah. The Skin Picking Scale-Revised (SPS-R) scale was administered to a convenience sample of 520 respondents. A partial least squares path model (PLS-PM) for "impairment" and "symptoms severity" subscales was assessed by evaluating the validity of measurement and structural models. Skin picking behavior was reported by 28.8% (n=150). A significant level of skin picking disorder symptoms was present in 1.2% (n=6). Skin picking visual effect, depressive symptoms, and being unmarried were the only positive independent predictors of the total SPS-R score. SPD symptoms are relatively common among the adult population in Jeddah, but those with threshold symptoms indicative of SPD are relatively few. Such behavior is particularly common in vulnerable groups such as those with depressive symptoms and the unmarried. More attention to this condition by clinicians will improve the quality of life of those affected, and reduce the emotional and physical health consequences of this often unrecognized condition.

Significance of family history in understanding and subtyping trichotillomania

Background and aimsThe existence of subtypes of trichotillomania (TTM) have long been hypothesized, and recent studies have further elucidated characteristic subtypes of TTM and possible ramifications of subtyping for treatment. In clinical applications of subtyping for treatment of TTM, family history (FH) of psychiatric disorders in patients may serve as a tool to differentiate disorder presentations and inform care. We compared prevalence of psychiatric illnesses in first-degree relatives of participants with TTM and healthy controls, respectively, in a large sample, and examined associations between those psychiatric disorders that were significantly different in the FH between groups and measures of disability, severity, and neuropsychological constructs. MethodsWe compared FHs of 152 participants (mean age = 29.9) with TTM and 71 healthy controls (mean age = 29.6), utilizing chi-squared tests to determine which psychiatric illnesses were more prevalent in FHs of participants with TTM. We then used two-tailed t-tests to compare TTM participants with those more prevalent FHs to participants without those FHs on measures of disorder severity, disability, and neuropsychological constructs. FindingsObsessive-compulsive disorder (OCD), TTM, skin picking disorder (SPD), and major depressive disorder (MDD) were significantly more frequent in first-degree relatives (p < 0.0033) of TTM participants than those of healthy controls. TTM participants with a FH of OCD scored significantly higher on measures of impulsivity and lower on measures of distress tolerance. Those with FH of TTM, SPD, and MDD did not differ significantly across measured variables. ConclusionOCD, TTM, SPD, and MDD are more prevalent in the FHs of people with TTM, as compared to healthy controls. TTM participants with a family history of OCD may be more likely to demonstrate decreased distress tolerance and increased impulsivity. In all, as understanding of TTM subtypes develops, the FH may prove a useful tool in delineating subtypes and informing care.

Internet-delivered acceptance-based behavior therapy for trichotillomania and skin-picking disorder in a psychiatric setting: A feasibility trial

Trichotillomania (TTM) and skin-picking disorder (SPD) are two clinically related conditions that can be successfully treated with behavior therapy (BT). There is some research indicating that BT for TTM and SPD can be efficacious also when delivered online instead of face-to-face, however, previous studies have mainly used self-recruited samples in a university context and it is unclear if the effects of online BT also extend to regular psychiatric patients. The current study set out to investigate if internet-delivered BT (I-BT) is a feasible, acceptable and preliminarily efficacious treatment for patients in a routine psychiatric setting. Twenty-five adult clinician-referred patients with TTM (n = 7) and/or SPD (n = 18) received 10 weeks of therapist-guided I-BT. The I-BT program incorporated both traditional interventions (e.g. habit reversal) as well as more recent acceptance-based techniques (e.g. embracing the urges and mindfulness). Clinician- and self-rated outcomes were assessed at pretreatment, posttreatment and at the delivery of 4 additional booster modules. Results showed that the majority of the participants were satisfied with the treatment and found it credible. The average number of completed internet modules was 7.2/10; five participants ended treatment prematurely. Significant decreases in hair pulling and skin picking severity were demonstrated from pretreatment to posttreatment with within-group effect sizes ranging from d = 0.89 to 1.75. The results remained significant up to the 12-month follow-up on most outcome measures. Altogether, the results provide initial evidence suggesting that I-BT could be a feasible, acceptable and potentially effective treatment for TTM and SPD for patients in a regular psychiatric setting.

Characteristics of 262 adults with skin picking disorder

IntroductionSkin picking disorder (also known as excoriation disorder or dermatillomania) is a common mental health disorder currently classified as an obsessive-compulsive and related condition. Despite being first described in the 1800s, very little is known about its phenomenology and clinical presentation. Most information about this disorder to date is based on online surveys rather than in-person assessments. MethodsClinical and demographic data were collected from individuals with skin-picking disorder taking part in research studies, using in-person assessments comprising validated instruments. Descriptive information was presented as to the nature of skin picking disorder. ResultsThe sample comprised 262 individuals, mean age 32.5 years, being 87% female. The peak age of onset of symptoms was 12.9 years, and most affected individuals (>90%) had symptom onset before age of 20 years. Typically, individuals reported picking from multiple body sites (most common was the face), and the most frequent triggers were stress and the ‘feel’ (i.e. texture) of the skin. Comorbidities were common, including trichotillomania, depression, generalized anxiety disorder, and impulsive/compulsive disorders (especially attention-deficit hyperactivity disorder and obsessive-compulsive disorder). The majority of people with the disorder (87.1%) had never received treatment. Of those who had received treatment in the past, 87% reported that they found the treatment helpful for their symptoms. DiscussionThis study sheds new light on the clinical presentation and phenomenology of skin picking disorder. Results highlight the need for further research into its clinical presentation, longitudinal course, and treatment approaches.

Characteristics and treatment seeking in an adult Hispanic population with trichotillomania and skin picking disorder

This study reports on characteristics of trichotillomania (TTM) and skin picking disorder (SPD) in an international Hispanic sample of adults. The survey was distributed online globally to a Hispanic population with TTM and SPD. 166 Hispanic adults with TTM (n = 127) or SPD (n = 39) reported moderate levels of symptom severity and low or very low quality of life. Anxiety disorders and OCD were common comorbidities. Hispanic adults with TTM and SPD were more impulsive and compulsive compared to non-Hispanic speaking adults (n = 92). Of the 166 subjects, 129 (77.7%) reported previously seeking treatment. When asked about the challenges they faced in seeking help, 67 (40.4%) identified a lack of therapists, psychologists, and psychiatrists who were knowledgeable about these disorders.

Skin Picking Scale-Revised: Diagnostic accuracy and optimal cut-off scores in university and psychiatric settings

The Skin Picking Scale-Revised (SPS-R) is an eight-item self-report measure of skin picking disorder (SPD) severity. The aim of this study was to examine the diagnostic accuracy of the SPS-R and develop cut-off scores in university and psychiatric settings. We administered the SPS-R to (1) university students with SPD (n = 73) and without SPD (n = 148) and (2) patients in a psychiatric partial hospital with SPD (n = 50) and without SPD (n = 403). Scores on the SPS-R accurately predicted SPD diagnostic status in both samples (area under the curve >0.95). A total score of 9 demonstrated an optimal balance between sensitivity, specificity, and predictive values in both samples. The results suggests that SPS-R has acceptable diagnostic accuracy and can be used as a screening tool to help identify individuals with SPD for research purposes in university and partial hospital settings.

Assessing Excoriation (Skin-Picking) Disorder: Clinical Recommendations and Preliminary Examination of a Comprehensive Interview.

Excoriation (skin-picking) disorder (SPD) is a psychiatric condition with variable clinical presentation. We developed the Diagnostic Interview for Skin Picking Problems (DISP), a semi-structured interview designed to assess (1) DSM-5 criteria for SPD and (2) several clinical features of SPD, including the frequency and duration of picking episodes, and the proportion of time devoted to picking at different body areas. The DISP was administered along with other measures to 120 college students (88% women, average age = 22 years) with suspected skin picking problems (based on their responses to a screening survey). The results showed that the DISP had good inter-rater reliability, test–retest reliability over 1–5 months, and convergent/divergent validity. We also found that participants displayed divergent clinical characteristics depending on the pattern of frequency, duration, and body location of picking episodes (e.g., those who primarily picked at the fingers had a unique clinical presentation). Overall, the findings provide preliminary support for the psychometric properties and clinical utility of DISP. The results also underscore the importance of accurately assessing frequency, duration, and body location of picking episodes.

Emotion regulation and executive functions in adolescents with skin picking disorder

Aim This study aimed to investigate emotion regulation difficulties and executive functions of adolescent outpatients with skin picking disorder (SPD). Method Ninety six adolescents with SPD and ninety healthy controls were included in the study. All patients were diagnosed with SPD as per the diagnostic criteria of DSM-5. A battery of tests were implemented to evaluate emotional regulation strategies (i.e. acceptance,), as well as associations between those strategies and executive functions, and clinical variables (anxiety, depressive symptoms, impulsivity and illness characteristics). Results The SPD group had significantly higher scores in inhibition (t = 2.982, p = 0.030), emotional control (t = 2.461, p = 0.016), and planning-organization (t = 2.139, p = 0.038) Multiple linear regression model explained a considerable amount of variance of executive functions in the patient group (Adjusted R 2=66.4%). In the patient group, age at illness-onset and the severity of inhibiton were significantly associated with the disruptions in emotional control functions (For age at illness-onset, β= −0.45, t=-3.0, p = 0.012 and for BRIEF Inhibition scores, β = 0.31, t = 2.8, p = 0.008). Conclusion The results of this study suggest that those with SPD have more emotion regulation problems and poorer executive function skills compared to those without SPD. Deficits in emotional control were associated with inhibition process and age-onset of the illness.

The role of compulsivity in body-focused repetitive behaviors

Trichotillomania (TTM) and skin picking disorder (SPD) have been characterized as body-focused repetitive behaviors (BFRBs) and have been grouped in the DSM-5 as part of the obsessive-compulsive and related disorders. Despite the clinical similarities between BFRBs and the compulsions of OCD, there has been little research regarding the degree to which compulsivity underpins these behaviors. 88 adults (69 female; mean age 30.9 years) with DSM-5 TTM or SPD completed standard diagnostic interviews, basic demographic information, symptom inventories about TTM and SPD, and measures of disability/functioning. Compulsivity was measured using the 15-item Cambridge-Chicago Compulsivity Trait Scale (CHI-T). Relationships between CHI-T scores and the other measures of interest were characterized using Pearson's correlations. Of the 88 participants, 48 (54.5%) had TTM, 37 (42.0%) had SPD and 3 (3.4%) had both. CHI-T total scores correlated with worse disability and quality of life but not with BFRB symptom severity. This study demonstrates that compulsivity is a marked contributor to worse disability and quality of life in people with BFRBs, more so than conventional measures of BFRB symptom severity (which did not correlate with disability/quality of life). Future work should include compulsivity measures in BFRB studies (including treatment trials) and explore its role in other related disorders.

Facial emotion recognition difficulties may be specific to skin picking disorder, but could also be related to the presence of alexithymia in trichotillomania

Background and objectivesPrevious research has shown high rates of alexithymia and emotion dysregulation in trichotillomania (TTM) and skin picking disorder (SPD). Unfortunately, there are no data on facial emotion recognition (FER) in TTM and SPD. The present study aimed to compare patients with TTM and SPD and a healthy control group for the severity of alexithymia and rates of FER. MethodsForty patients with SPD, 30 patients with TTM, and 30 healthy controls were enrolled in this study. The Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Clinical Global Impression (CGI), Toronto Alexithymia Scale (TAS-20), and the Facial Emotion Recognition Test were applied to the participants. ResultsPatients with TTM and SPD had less FER accuracy and higher alexithymia scores compared with healthy controls. According to ANCOVA analysis, when anxiety, depression, and alexithymia were fixed as covariates, disgusted facial expressions and total facial emotion recognition were still significantly lower in patients with SPD compared with the control group, but there was no difference between the TTM and control groups and TTM and SPD groups. ConclusionAlexithymia rates were high in patients with TTM and SPD. Interestingly, difficulty in recognizing disgusted facial expressions may be a distinctive sign in SPD. Future neuroimaging studies are needed to support possible FER impairment in patients with TTM/SPD.

Pain perception and physiological correlates in body-focused repetitive behavior disorders.

Behaviors typical of body-focused repetitive behavior disorders such as trichotillomania (TTM) and skin-picking disorder (SPD) are often associated with pleasure or relief, and with little or no physical pain, suggesting aberrant pain perception. Conclusive evidence about pain perception and correlates in these conditions is, however, lacking. A multisite international study examined pain perception and its physiological correlates in adults with TTM (n=31), SPD (n=24), and healthy controls (HCs; n=26). The cold pressor test was administered, and measurements of pain perception and cardiovascular parameters were taken every 15seconds. Pain perception, latency to pain tolerance, cardiovascular parameters and associations with illness severity, and comorbid depression, as well as interaction effects (group×time interval), were investigated across groups. There were no group differences in pain ratings over time (P=.8) or latency to pain tolerance (P=.8). Illness severity was not associated with pain ratings (all P>.05). In terms of diastolic blood pressure (DBP), the main effect of group was statistically significant (P=.01), with post hoc analyses indicating higher mean DBP in TTM (95% confidence intervals [CI], 84.0-93.5) compared to SPD (95% CI, 73.5-84.2; P=.01), and HCs (95% CI, 75.6-86.0; P=.03). Pain perception did not differ between those with and those without depression (TTM: P=.2, SPD: P=.4). The study findings were mostly negative suggesting that general pain perception aberration is not involved in TTM and SPD. Other underlying drivers of hair-pulling and skin-picking behavior (eg, abnormal reward processing) should be investigated.