Skin Cleansing Research Articles

PHYSICAL PROPERTIES AND CHEMICAL CONSTITUENTS ON DRAVYA OF MUKHALEPA: A LITERARY REVIEW

Skin is the body's largest organ and has excellent cosmetic value. It is one of the five gyanendriya (sense organs). i.e., sparsha gyan (touch sensation) gets from it. So, it has immense importance for an individual's physical and mental well-being. It is most vulnerable to diseases as it exposes to the external environment. There are many reasons behind skin problems; the most striking is today’s busy and stressful life. Skin disorders affect all ages, from neonates to elderly persons. Ayurveda has explained vast descriptions of lepa kalpana, of various skin diseases and beauty. The medicines in the form of a paste used for external applications are called lepas. Ayurveda has explained a lot of things which are unique concepts about beauty and also an effective and cheaper, long-lasting therapy without any side effects. Mukha lepa (face pack) is a concept in which a thick and consistent paste is applied on the face to treat acne, pimples, scars, marks and pigments in Ayurveda Mukha lepa is simply effective skin care treatment mainly for the nourishment of skin and also aids in skin cleansing and make it soft and transparent. Mukha lepa also helps to increase the skin's elasticity and thereby prevents skin ageing, avoids wrinkles on the face and gives a good elasticity and tone. The primary purpose of this article is to provide details about the lepa kalpana from Ayurveda, which offers more benefits to the skin for complexion and skin ailments.

Antibacterial activity test of celery leaf (Apium graveolens) extract liquid hand soap against Staphylococcus aureus

Personal and environmental hygiene must be considered to prevent the transmission of COVID-19. One of them is by washing hands with soap. Liquid soap is a skin cleanser made from soap-based ingredients and added surfactants, preservatives, foam stabilizers, fragrances, and dyes. The basic ingredients for soap can be natural, one of which is essential oil. Celery contains essential oils (alinin and allicin), flavonoids, protein, vitamin A, vitamin C, vitamin B, iron, calcium, sulfur, and phosphorus. Essential oil from celery has activity as an antifungal and is active against many bacteria, including Staphylococcus aureus. This study aims to determine the celery extract liquid hand soap has antibacterial activity against Staphylococcus aureus bacteria and the effective concentration of celery leaf extract liquid hand soap on the antibacterial activity of Staphylococcus aureus. The research method was laboratory experimental by testing the antibacterial activity of liquid hand soap formulations of celery leaf extract. The results of the organoleptic test were green in color, in viscous liquid form, and had a distinctive celery aroma. The pH test obtained a pH of 9.4 in the 5% formulation (FI), pH 9.5 in the 10% formulation (FII), and pH 9.3 in the 15% formulation (FIII). Antibacterial activity test FI, FII, FIII, negative control, and positive control resulted in a diameter of 17.1 mm inhibition zone; 23.2 mm; 17.4 mm; 0 mm, and 22.9 mm. The results of the one-way ANOVA test obtained a p-value <0.05, which indicated that H1 was accepted, i.e., liquid hand soap with celery leaf extract had antibacterial activity against Staphylococcus aureus. The Tukey test showed that the diameter of the FII inhibition zone (10% concentration) was close to that of the positive control inhibition zone. The most effective concentration is 10% (FII), with a very strong inhibition category.

Uso da radiofrequência no tratamento da acne: uma revisão sistemática

ABSTRACT Acne, of great prevalence and impact, presents many forms that can be treated by hygiene, topical medications, and manual alternative interventions such as skin cleansing and electrotherapy. The use of radiofrequency in the treatment of acne aims to increase the temperature in the cutaneous tissue, causing several metabolic and structural reactions, such as stimulating neocollagenesis. This study aimed to investigate the use of high-frequency current as an adjunctive treatment for acne. This is a non-systematic review of indexed databases (MEDLINE, SciELO, LILACS). A total of 18 studies were included in this review and most of them related different treatment for acne associated with radiofrequency. Radiofrequency presents few complications and good results, besides having as an additional advantage the possibility of the patient returning to the routine immediately after application.

Knowledge, Attitudes, and Practices Regarding Skin Care in Saudi Arabia: A Cross-Sectional, Survey-Based Study.

Skin care is the maintenance of the hygienic state of the skin toward optimal conditions of cleanliness and comfort and includes skin cleansing, skin product use, and photoprotection. This study aimed to assess skincare knowledge, attitudes, and practices among Saudi populations. This cross-sectional study was conducted in Saudi Arabia from February to April 2022. Data were collected using a survey distributed through social media to participants of both genders aged 12 years and above. A total of 710 subjects participated in this study. More than half were aged between 18 and 30 years (54.8%), had a bachelor's degree (56.2%), had no income (55.8%), and resided in the Western region (58.0%). Females represented most respondents (77.3%). Skin disease was prevalent among 19.9% of the population. The combined skin type was most frequently reported for the face (52.1%), while for the body, the dry skin type predominated (42.8%). Using skincare products was significantly associated with the female gender (p < 0.001). The knowledge and practices concerning of skin care are acceptable within the Saudi population. Being a female and having oily facial skin influenced skincare behavior the most among the Saudi population.

Comparison of Different Anti-Demodex Strategies: A Systematic Review and Meta-Analysis

Background: Demodex mites are related to some inflammatory diseases such as rosacea and blepharitis and could be harmful in patients with immunodeficiency or immunosuppression, especially notable in patients using biologic like dupilumab. In order to have an objective observation of different anti-Demodex strategies, we conducted this study, based on interventional clinical evidence with quantified Demodex mite data. Methods: We used the PubMed, Embase, ClinicalTrials.gov, Medline, and International Clinical Trials Registry Platform (ICTRP) as databases. To assess the risk of bias, the RoB2 and ROBINS-I tools were used. The certainty of evidence was assessed following the GRADE guideline. Furthermore, the effect sizes (ESs) of different strategies were compared in different time periods (0–1, 1–2, 2–3, >3 months), as well as Demodex decrease rates. Results: 1,618 studies were identified in the databases, with 21 of which included in the final quantitative synthesis. Interventions in these studies included ivermectin, tea tree oil (TTO), permethrin, crotamiton, metronidazole, light therapies, combined therapies, and other therapies. During 0–1 month, the ES varied from 0.07 (cleanser) to 1.95 (systemic ivermectin-metronidazole). During 1–2 months, the ES varied from 0.88 (topical permethrin) to 4.40 (topical ivermectin). During 2–3 months, the ES varied from 0.79 (topical permethrin) to 8.37 (topical ivermectin). During the time of 3 months, the ES varied from 0.59 (topical permethrin) to 2.25 (intense pulsed light [IPL]). In terms of Demodex decrease rates, topical ivermectin, TTO, permethrin, IPL, and baby shampoo had achieved a nearly 100% decrease. The reported adverse events were mostly mild, without severe adverse events reported in any of the studies. Conclusions: We found ivermectin (topical and systemic), ivermectin-metronidazole (topical), and TTO (topical) are promising anti-Demodex interventions. In addition to traditional pharmacotherapy, light therapies, especially IPL and skin cleansing, could also be considered as effective methods to control Demodex mite infestation.

Evaluating the effectiveness of octenidine-containing wash mitts in reducing infections in intensive care.

Patients in intensive care units (ICUs) are at a greater risk of developing hospital-acquired infections (HCAIs). Decontamination, which usually includes a regimen of body washing with an antimicrobial skin cleanser, is used to prevent HCAIs. Approaches can be: targeted, where carriers are identified and decontaminated; or universal, where all patients undergo a decontamination regimen. Universal rather than targeted decontamination is more effective at reducing infection rates and is more cost-effective. Decontamination in the ICU can lower HCAI rates across the entire hospital. Microbial resistance to chlorhexidine, however, which is the main active agent used for decontamination is increasing, and there are also adverse effects, leading to interest in octenidine as an alternative. This article explores the use of octenidine-containing single-use wash mitts in ICUs, which have been positively evaluated regarding antimicrobial activity, and ease and effectiveness of use.

33260 Dermal delivery of 12-hydroxystearic acid for barrier benefits from skin cleansers – An ex vivo and in silico study

12-hydroxystearic acid (12-HSA) is known to benefit skin barrier function and immunity as demonstrated from cell culture and reconstructed tissue experiments However, dermal penetration of 12HSA has not been well studied, particularly when deposited from cleansers. To assess the effectiveness of delivering 12-HSA to the viable epidermis (VE) from cleansers via ex-vivo measurements and validation of established in silico simulation methods for this active. 12-HSA delivery was quantified using ex vivo dermal delivery measurements. The transdermal delivery data was used to validate results obtained from in silico simulation and further insights on 12HSA delivery were then obtained from the simulations. Both ex vivo and in silico results showed 12-HSA can be successfully delivered to the VE in a dose-dependent manner. We show that we can attain ∼10uM or higher concentrations of 12-HSA in the VE within 24 hours from a single use of cleanser. At such levels 12-HSA has been demonstrated to enhance skin biological processes. Further, simulations predicted that a higher level of 12-HSA can be achieved and maintained at a stable level in the VE after three daily cleanser applications. These results suggested that it is feasible to deliver 12-HSA from cleansers at a level which can provide a functional benefit for skin health.

32763 Cleansing efficacy of mild facial cleansers for sensitive skin

Skin cleansing is a major part of our daily routine in modern life. While traditional cleansing liquids are highly effective at removing dirt, makeup, oil and sunscreen, they can also disrupt natural skin barriers such as essential skin lipids, which protect our skin from overdrying and becoming too sensitive to the surroundings. This kind of harsh cleansing can reduce natural moisturizing factors (NMF) and potentially cause problems for those with sensitive skin. Thus, mild facial cleansers have become highly popular in recent years.

Comparison of two skin protection regimes for the Prevention of Incontinence-associated Dermatitis in geriatric care (PID): a study protocol for an exploratory randomised controlled pragmatic trial

IntroductionThe majority of aged long-term care receivers and patients in geriatric acute care are affected by some form of incontinence. These individuals are at risk of developing incontinence-associated dermatitis (IAD),...

Kinder, Gentler Presurgical Skin Prep

<h3>Introduction</h3> Patients routinely are prepped with a skin cleanser and antiseptic during preoperative preparation for surgery. This type of prep is best practice for all surgeries. <h3>Identification of the problem</h3> Current pre-op skin preparation product, Medline CHG (Medline) was causing unacceptable skin reactions in patients. Multiple surgeons requested that Medline use be discontinued. Lack of skin bioload reduction adds risk for infection. <h3>Question/Purpose of the study</h3> Are there other CHG skin prep products which will adequately cleanse and reduce bioload on skin areas and would decrease and/or eliminate adverse skin reactions in patients? <h3>Methods</h3> After extensive research, Sage CHG (Sage) was trialed on randomly selected patients during preoperative preparation while Medline use was continued on all others (i.e., control group). The trial period was three-months (6/1/21-8/31/21) with the first two months in outpatient surgery patients while the third month consisted of all surgical patients. <h3>Outcomes/Results</h3> During the trial period there were a total of 989 cases where Medline was used and 829 cases where Sage was used, resulting in 11 and 3 cases of adverse skins reactions, respectively. Of the 11 adverse reactions with the use of Medline, 3 required additional inpatient care while 2 required emergency department treatment. There were no adverse outcomes with Sage. There was no increase of postoperative infection during the trial using Sage. <h3>Discussion</h3> Published product data indicates that Medline contains agents that are known skin irritants, namely isopropyl alcohol, and benzalkonium chloride while Sage contains neither and in addition contains skin humectants and emollients which protects and hydrates the skin. During the trial period, relative adverse skin reactions were 3.07 times higher with use of Medline as opposed to Sage. P value=.0092 <h3>Conclusion</h3> The use of Sage during preoperative patient preparation is preferred over Medline as adverse skin reactions were minimized with no infection increase. Full conversion to the Sage product started 9/1/21. <h3>Implications for perianesthesia nurses and future research</h3> As the integumentary system is critical for physical protection and infection control, effective preoperative skin preparation is crucial for postoperative infection control, minimization of adverse skin reactions and patient comfort. Use of the most nonirritant skin preparation during the preoperative phase contributes to all three.

Development of an imputation model to recalibrate birth weights measured in the early neonatal period to time at delivery and assessment of its impact on size-for-gestational age and low birthweight prevalence estimates: a secondary analysis of a pregnancy cohort in rural Nepal

ObjectivesIn low-income countries, birth weights for home deliveries are often measured at the nadir when babies may lose up of 10% of their birth weight, biasing estimates of small-for-gestational age...

Formulasi Sediaan Kosmetik Facial wash Ekstrak Etanol Daun Kelor (Moringa oleifera L.) dengan Variasi Konsentrasi Sodium Lauryl Sulfat

Moringa leaves (Moringa oleifera L) contains tannins, flavonoids and sapoins compounds, that function as antibacterials. This study aims to formulate a facial wash preparation from the ethanol extract of Moringa leaves as a facial skin cleanser. The ethanol extract of Moringa leaves was made in the form of 3 facial wash preparation formulas with a concentration of 3%, and different Sodium lauryl sulfate, namely FI (1%), FII (1.5%) and FIII (2%). Prior to the formulation, Moringa leaves were macerated with 96% ethanol to obtain a thick extract. Then proceed with organoleptic testing, pH testing, homogeneity testing and foam height testing. The results of the study on the evaluation of facial wash preparations of ethanol extract of Moringa leaves FII and FIII with SLS concentrations of 1.5% and 2% showed the best formulation compared to F1

Formulation and Evaluation of Polyherbal Scrub

The main purpose of our research was to produce gelled Polyherbal scrubs. In the daily lives of women and men, cosmetics play a role in changing the appearance of the skin. Most cosmetics on the market dry when applied to the skin, remove darkening after use and shorten the lifespan of skin problems such as acne and redness. The solution to this problem is to use an exfoliating gel once or twice a week. All of these are herbal ingredients that enhance skin cleansing, softness, moisturization and impartiality. Plant-based cosmeceuticals usually contain some of the plants with antibacterial, antioxidant, and anti-aging properties. The active ingredients used in this formulation are green tea, aloe vera gel, rice flour, sandalwood flour, casturihardi, almond oil, mint, saffron carrot juice, orange peel powder and coffee. Other ingredients such as methylparaben, triethanolamine, etc. were added to the gel along with sodium lauryl sulfate. The resulting gel was evaluated for various parameters such as appearance, pH, viscosity, spreadability, detergency, and hypersensitivity, and was found to be sufficient for all required characterization. Therefore, the developed formulation can be used as an effective exfoliating agent to maintain healthy and shiny skin.

Chlorhexidine as a Keap1-Nrf2 inhibitor: a new target for an old drug for Parkinson's disease therapy

Oxidative stress plays a vital role in the pathophysiology of most neurodegenerative diseases such as Parkinson's disease (PD). The Keap1-Nrf2-ARE pathway, one of the internal defense mechanisms, curbs the reactive oxygen species (ROS) generated in the cellular environment. The pathway leads to the expression of antioxidant genes such as HO-1, GCLC, and NQO1, which act as cellular redox switches and protect the cellular environment. Keap1, the negative regulator of Nrf2, is a potential therapeutic target for treating age-related neurodegenerative diseases. Tecfidera (Dimethyl fumarate), used in the intervention for relapsing multiple sclerosis, is the only commercial drug known to regulate the Nrf2 function. Here, we have identified a repurposing drug, chlorhexidine (LBP125), through ligand-based pharmacophore development and screening against the DrugBank, as a potential inhibitor of the β-propeller domain of Keap1 (Keap1-DC). Chlorhexidine, an antimicrobial agent, is widely used as a mouthwash, skin cleanser, and intervening bacterial infection during childbirth. The biochemical assay confirmed a significant binding affinity of 30 µM and competitively inhibited the Nrf2 peptide interaction. Moreover, chlorhexidine also exerts cytoprotection in a neurotoxic cell model of PD through Keap1-Nrf2 disruption leading to nuclear translocation of Nrf2 and expression of downstream genes, HO-1, and NQO1. Hence, the chemical scaffold of chlorhexidine is a potential lead to develop new chemical libraries with drug-like properties for treating PD. Communicated by Ramaswamy H. Sarma

Development of a comprehensive method for the dermatoscopic images analysis of the facial skin with acne

Background: One of the most common inflammatory chronic and recurrent skin diseases is acne (“acne vulgaris”), which appears itself as open or closed comedones and inflammatory skin lesions in the form of papules, pustules, nodes, etc. It has been established that acne is one of the most common dermatoses, since, according to modern data, it affects about 9.4% of the population. During adolescence, up to 90% of people suffer, and in adulthood — about 20% with varying degrees of severity. Currently, there are many approaches to treating this disease through various cosmetic treatments such as phototherapy, ultrasonic skin cleansing, Mesotherapy, chemical peels, and medication. Therefore, the development of methods and means of differential diagnosis of acne is one of the urgent tasks in the field of biomedical engineering, dermatology, and clinical medicine, since this allows timely identification of the localization of the disease, its causes, and prescribing appropriate treatment. However, the solution to the problem of monitoring the dynamics of external manifestations of the disease is possible only with the use of combined mathematical methods for image analysis. Objectives: To develop a comprehensive method for analyzing dermatoscopic images for monitoring the external manifestations of acne disease during treatment and isolating the affected areas of the facial skin. Materials and Methods: Dermatological preclinical researches of the skin were conducted in the laboratory of 3D-biomedical technologies of the Department of Biomedical Engineering of the Kharkiv National University of Radio Electronics, using a digital videodermatoscope BIO Bm6+ in daylight and a portable skin analyzer Skin Scope F-102 in the ultraviolet range. Clinical researches were conducted based on the Department of Pediatric Propaedeutics #2 of the Kharkiv National Medical University. The development of a software tool for image analysis was conducted out in Python programming using the libraries OpenCV, Scikit-image, Numpy, PIL, Mathplotlib. Determination of the affected skin areas and calculation of the parameters of inflammation were carried out using multi-Otsu methods and morphological segmentation of digital dermatoscopic images. Results: During the research, automated software was developed that allows to analyze in dynamics the nature of inflammatory processes and the area of facial skin lesions, as well as to carry out a differential diagnosis of acne disease. The proposed method for the analysis of dermatoscopic images makes it possible to perform color segmentation and obtain a map of the gradations of skin inflammations to control the dynamics during the prescribed treatment. Conclusions: The comprehensive method of analysis of dermatoscopic images of the skin of the face makes it possible to effectively control the condition of the skin of the face from acne during treatment, while analyzing the degree of inflammatory processes and the area of lesions, where, using the developed software, in an automated mode, red gradations are calculated to detect the boundaries of inflammation, geometric parameters and percentage of lesions in relation to healthy facial skin.

Acceptance of skin products in healthcare workers: an empirical investigation.

BackgroundHealthcare workers (HCWs) are at high risk of developing hand eczema (HE). This can be exacerbated by hygiene measures related to the coronavirus disease (COVID-19). Using mild skin cleansers and emollients or moisturizers is central in the prevention of HE—especially with increased COVID-19 hygiene regimes.AimsThis study aimed to assess parameters important for the acceptance of a skincare concept in HCWs.MethodsIn this proof-of-concept user trial, HCWs were provided ad libitum with hand wash oil and hand cream during the 6-month period, when occupationally acquired COVID-19 infections among HCWs were peaking in Germany and then surveyed about acceptance of the products using questionnaires.ResultsOf 135 HCWs, 115 (85%) responded. Skin tolerance of the hand wash oil and the hand cream was rated very good by 63% and 52% of the 115 participants, respectively. Of the 115 participants, 58% and 57% were very satisfied with the hand wash oil and the hand cream, respectively.ConclusionsAcceptance of skin cleansing and skincare products in HCWs seems influenced by parameters such as self-assessed skin tolerance and self-reported overall satisfaction. It must be assumed that products are only used as recommended if they are well-accepted. Employers might survey employees about acceptance of products using the parameters identified to adjust concepts if necessary to sustainably contribute to the prevention of HE.

Patch testing with glucosides: The North American Contact Dermatitis Group experience, 2009-2018

BackgroundAlkyl glucosides are nonionic surfactants that are increasingly used in personal care products. ObjectiveTo characterize positive patch test reactions to decyl glucoside (5% petrolatum, tested 2009-2018) and lauryl glucoside (3% petrolatum, tested 2017-2018). MethodsRetrospective analysis of patients tested by the North American Contact Dermatitis Group. ResultsOf 24,097 patients patch tested to decyl and/or lauryl glucoside, 470 (2.0%) had positive reactions. Compared with glucoside-negative patients, glucoside-positive patients had higher odds of occupational skin disease (13.4% vs 10.1%; P = .0207), history of hay fever (38.5% vs 31.6%; P = .0014), atopic dermatitis (39.0% vs 28.6%; P < .0001), and/or asthma (21.8% vs 16.5%; P = .0023). Most glucoside reactions (83.9%) were currently relevant. The most common source was personal care products (63.0%), especially hair products (16.5%) and skin cleansers (15.2%). Of 4933 patients tested to decyl and lauryl glucoside, 134 (2.7%) were positive to 1 or both; 43.4% (43 of 99) of decyl-positive patients were also positive to lauryl glucoside and 55.1% (43/78) of lauryl glucoside patients were also positive to decyl glucoside. LimitationsThe cohort predominantly reflects a referral population, and follow-up after testing was not captured. ConclusionGlucoside positivity occurred in 2.0% of the tested patients. Reactions were often clinically relevant and linked to personal care products. Cross-reactivity was >40%.

Justification of nurses' interventions for skin cleansing and skincare: Qualitative results of the SKINCARE-Pilot study

Justification of nurses' interventions for skin cleansing and skincare: Qualitative results of the SKINCARE-Pilot study Abstract. Background: Skin care interventions are core tasks of nursing. Various factors influence the implementation of evidence-based care. Aims: To explore the perspectives of nursing staff on the relevance of skin care interventions in long-term care settings and the justification of clinical decisions about the application of such interventions. Methods: Qualitative part of a mixed methods study in three long-term-care facilities, consisting of short interviews with nursing staff members directly after nursing assistance with personal hygiene, focus group discussions with nursing staff members, and semi-structured interviews with nursing managers. The data were analyzed by means of content analysis. Results: The sample (N = 30) comprises 10 short interviews, 3 focus groups (n = 17), and 3 individual interviews. Nurses predominantly assigned a high relevance to nursing support in personal hygiene. As a basis for their decision-making, residents' needs and preferences, nurses' personal knowledge as well as own experiences and preferences were reported. Evidence-based sources of knowledge were hardly mentioned. The availability of skin cleansing and skin care products, staff and time resources, and nurse-physician cooperation were identified as influencing factors. Conclusions: Decisions about nursing support in personal hygiene seem poorly informed by evidence-based sources for clinical decision-making. Evidence-based decision support could facilitate the use of appropriate nursing interventions.

Effects of skin washing frequency on the epidermal barrier function and inflammatory processes of the epidermis: An experimental study.

Increased hand hygiene measures during the COVID-19 pandemic have led to an increased quantum of hand eczema (HE). To examine the effects of varying washing frequencies using current mild cleansing agents-alongside with the effect of a rehydrating cream-on the epidermal barrier function and inflammatory processes of the stratum corneum(SC). Standardized skin washings on the volar aspects of the lower arms of skin-healthy volunteers were performed using the automated cleansing device either 5 or 11 times within 4h for 60 s each with a standard cleanser, a lipid-containing syndet, or a lipid-containing syndet followed by one-time application of a rehydrating cream. Skin bioengineering parameters (transepidermal water loss, SC hydration, erythema, and SC pH) and biochemical/immunological parameters (interleukin-1α, interleukin-1α receptor antagonist and natural moisturizing factor) of SCsamples collected by tape stripping were assessed. All applied washing procedures provided comparable, mild effects on the epidermal barrier function and skin inflammation. Occupational skin cleansers seem to have improved regarding skin barrier damaging effects. To further corroborate this, a study design, modified on the basis of our findings, applying longer washing periods for consecutive days seems desirable.

Study of the Dilution-Induced Deposition of Concentrated Mixtures of Polyelectrolytes and Surfactants.

Mixtures of polyelectrolytes and surfactants are commonly used in many technological applications where the challenge is to provide well-defined modifications of the surface properties, as is the case of washing formulations in cosmetics. However, if contemporary experimental and theoretical methods can provide insights on their behavior in concentrated formulations, less is known on their behavior under practical use conditions, e.g., under dilution and vectorization of deposits. This makes it difficult to make predictions for specific performance, as, for example, good hair manageability after a shampoo or a comfortable sensorial appreciation after a skin cleanser. This is especially important when considering the formulation of new, more eco-friendly formulations. In this work, a detailed study of the phase separation process induced by dilution is described, as well as the impact on the deposition of conditioning material on negatively charged surfaces. In order to gain a more detailed physical insight, several polyelectrolyte–surfactant pairs, formed by two different polymers and five surfactants that, although non-natural or eco-friendly, can be considered as models of classical formulations, have been studied. The results evidenced that upon dilution the behavior, and hence its deposition onto the surface, cannot be predicted in terms of the behavior of simpler pseudo-binary (mixtures of a polymer and a surfactant) or pseudo-ternary mixtures (two polymers and a surfactant). In many cases, phase separation was observed for concentrations similar to those corresponding to the components in some technological formulations, whereas the latter appeared as monophasic systems. Therefore, it may be assumed that the behavior in multicomponent formulations is the result of a complex interplay of synergistic interactions between the different components that will require revisiting when new, more eco-sustainable ingredients are considered.