Spectral characterization of graphs is a well-studied topic in spectral graph theory which has received a lot of attention from researchers. The spectral characterization of oriented graphs, however, is less studied so far. Given a simple undirected graph G with an orientation σ, the oriented graphGσ is a digraph obtained from G by assigning to every edge of G a direction according to σ. An oriented graph Gσ is self-converse if it is isomorphic to its converse (Gσ)T, a graph obtained from Gσ by reversing each directed edge in Gσ. We denote by S(Gσ) the skew-adjacency matrix of Gσ. For two oriented graphs Gσ and Hτ with skew-adjacency matrices S(Gσ) and S(Hτ), respectively, we say Gσ is R-cospectral to Hτ, if for any t∈R, two matrices tJ−S(Gσ) and tJ−S(Hτ) have the same spectrum, where J is the all-one matrix. An oriented graph Gσ is said to be determined by the generalized skew spectrum (DGSS for short) if, any oriented graph R-cospectral to Gσ is isomorphic to Gσ.Oriented graphs that are DGSS must be self-converse. In this paper, we give a simple arithmetic condition for a self-converse oriented graph being DGSS, which provides an analogue of a similar result for ordinary graphs; see [15]. More precisely, let Gσ be a self-converse oriented graph with skew-adjacency matrix S(Gσ), and W(Gσ)=[e,S(Gσ)e,⋯,Sn−1(Gσ)e] (e is the all-one vector) be the skew-walk-matrix. We show that if 2−⌊n2⌋detW(Gσ) is odd and square-free, then Gσ is DGSS. Moreover, we also illustrate that our result is the best possible in certain sense.