Optimize the cab seat height of the heavy commercial vehicle and the maneuverability of the shift lever. Method: The mathematical model of human sitting posture and upper limb operation were established. The Chinese human body size was corrected by the combination of height growth rate and height linear ratio. Under the constraint of sitting posture, the H-point fitline model of the 5th, 50th and 95th percentile male drivers in China was obtained, and the optimal H-point range and SgRP point height were determined. The problem of high seat height has been optimized. At the same time, a operating lever layout position model is established; The actual measurement was made in the Class A vehicle, and the shift lever arrangement position was redefined. Conclusion: The height adaptability of the seat is improved; the operating comfort of the shift lever is improved; the visible area of the instrument panel becomes larger, and the 10th percentile male driver in China has a larger blind spot.