Abstract. With the publication of the subarea interim report on sub-regions on 28 September 2020, the Federal Company for Radioactive Waste Disposal (BGE), as the implementer of the German site selection procedure, has completed the first step of phase I in due time. The second step of phase I is the identification of siting regions for surface exploration. In the following step 2 of phase I, the determination of siting regions for surface exploration will be carried out based on the interim results of the first step of phase I in accordance with section 14 of the regulating law (StandAG). A central component of this second step of phase I is the representative preliminary safety assessments pursuant to section 27 StandAG, the ordinances on “Safety Requirements” (EndlSiAnfV) and “Preliminary Safety Assessments” (EndlSiUntV), which are carried out for each of the sub-regions. Based on the results of the preliminary safety assessments and the renewed application of the geoscientific weighting criteria (section 24 StandAG), siting regions will be identified that have the potential to become the site with the best possible safety for a repository for high-level radioactive waste. During the second step of phase I, the planning scientific consideration criteria (section 25 StandAG) can be applied for the first time. The path to the siting regions for surface exploration can be accompanied by various challenges related to geoscientific, methodological and also societal questions. For example, the application of the representative preliminary safety assessments may be more challenging in larger subareas compared to smaller ones as subsurface properties are likely to be more variable. In this context, areas with little data coverage for example, and the treatment of these areas in the procedure may pose another challenge. Therefore, sound methodological concepts must be developed for performing the representative preliminary safety assessments as well as for applying the geoscientific weighting criteria. Furthermore, the German site selection procedure defines special requirements (section 1 StandAG): the implementation of the participatory, science-based, transparent, self-questioning and learning procedure poses challenges to all stakeholders of the procedure on the way to the best possible disposal of high-level radioactive waste.